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Biochemistry news
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such ...
Biochemistry
Jul 12, 2024
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89
How to make an old antibiotic 100 times more potent
Nathaniel Martin, Professor of biological chemistry, wondered what would happen if you took an antibiotic that has been known for 70 years and tried to improve it with the latest tools of modern chemistry. Turns out it can ...
Biochemistry
Jul 12, 2024
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87
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by ...
Biochemistry
Jul 12, 2024
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19
Nanoplastics and 'forever chemicals' shown to disrupt molecular structures and functionality
Researchers at The University of Texas at El Paso have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS)—commonly known as forever chemicals—disrupt biomolecular ...
Biochemistry
Jul 11, 2024
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160
One-step synthesis of pharmaceutical building blocks: New method for anti-Michael reaction
In 1887, chemist Sir Arthur Michael reported a nucleophilic addition reaction to the β-position of α,β- unsaturated carbonyl compounds. These reactions, named Michael addition reactions, have been extensively studied to ...
Biochemistry
Jul 11, 2024
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Densely packed E. coli form an immobile material similar to colloidal glass, research shows
Dense E. coli bacteria have several similar qualities to colloidal glass, according to new research at the University of Tokyo. Colloids are substances made up of small particles suspended within a fluid, like ink for example. ...
Biochemistry
Jul 11, 2024
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25
Researchers claim photoluminescent aerogel has a visible light reflectance of 104%
A team of chemists and materials scientists at Sichuan University, in China, has developed a photoluminescent aerogel with a visible light reflectance of 104%. In their study, published in the journal Science, the group created ...
Photoenzymatic synthesis achieves efficient oxidation of fatty acids
A research team designed and built a photoenzymatic cascade by combining photochemical water oxidation/O2 reduction with P450 peroxygenase catalysis to achieve efficient visible-light-driven oxidation of a range of fatty ...
Biochemistry
Jul 8, 2024
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First set of rational design principles for chaotropic membrane transporters
The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, ...
Biochemistry
Jul 8, 2024
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1
Novel compound offers improved defense against fentanyl overdoses
Scientists at the University of Florida have identified a novel compound aimed at improving the treatment of opioid overdoses, which claimed the lives of more than 81,000 Americans last year.
Biochemistry
Jul 8, 2024
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10
Scientists sustainably create peptide-based medicines, pave way for greener cancer treatments
Scientists from the University of Manchester have uncovered a more efficient and sustainable way to make peptide-based medicines, showing promising effectiveness in combating cancers.
Biochemistry
Jul 8, 2024
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12
New probe reveals water-ice microstructures
Ice is believed to have played a crucial role in the emergence of life. One reason is that organic molecules can be excluded into the gaps between the crystal lattice by orderly arranged water molecules, leading to the concentration ...
Biochemistry
Jul 5, 2024
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240
AI approach optimizes development of antibody drugs
Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the ...
Biochemistry
Jul 5, 2024
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A closer look at cell toxins: Researchers examine how radionuclides interact with kidney cells
When radionuclides enter our organism, whether by inhalation, ingestion, or through wounds, they pose a potential health risk. Many previous studies on radionuclide exposure have focused mainly on animal experiments. However, ...
Biochemistry
Jul 4, 2024
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51
Exploring the molecular basis of how pradimicin A binds to viral N-glycan, a potential SARS-CoV-2 entry inhibitor
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are "enveloped viruses," viruses that have an exterior envelope that surrounds them largely composed ...
Biochemistry
Jul 3, 2024
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Study identifies novel host factors that facilitates SARS-CoV-2 entry
A research team led by Prof. Guo Yusong, Associate Professor of the Division of Life Science at the Hong Kong University of Science and Technology (HKUST), recently made a novel discovery related to the coronavirus (SARS-CoV-2) ...
Biochemistry
Jul 2, 2024
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New insights into antihistamine binding could lead to more effective treatments
Even if two molecules have the exact same chemical formula and the same number and types of bonds, their three-dimensional arrangements can still be different. While some people might mistakenly disregard this as a minor ...
Biochemistry
Jul 1, 2024
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Tannic acid-coated magnetic beads could facilitate early cancer diagnosis
Researchers have synthesized tannic acid-coated magnetic beads capable of extracting membrane vesicles called "exosomes" from biological fluids with 60% efficiency. This novel method will make it easier and faster to isolate ...
Biochemistry
Jul 1, 2024
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39
Engineered biocatalyst for making 'drop-in' biofuels
Researchers at the Department of Inorganic and Physical Chemistry (IPC), Indian Institute of Science (IISc), have developed an enzymatic platform that can efficiently transform naturally abundant and inexpensive fatty acids ...
Biochemistry
Jun 28, 2024
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75
Researchers create green solvent to boost lignin applications
Lignin, the glue that holds fibers together in trees and plants, is one of the most common yet one of the most complex biocomposites, because there are so many variants and qualities. Its heterogeneous chemical structure ...
Biochemistry
Jun 27, 2024
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Other news
Scientists demonstrate chemical reservoir computation using the formose reaction
Neural networks made of light can make machine learning more sustainable
