LUMICKS

Congratulations to Professor Mark Lowdell and Dr. Helena Arellano-Ballestero from UCL on their groundbreaking paper published in JITC! In this study, researchers thoroughly characterized memory-like NK (mINK) cells to better understand their potential for cancer treatments. They fully analyzed cell-cell binding (cell avidity) to elucidate the mechanism of action of mINK cells, which demonstrated superior functionality in vivo. H. Arellano-Ballestero et al., stated “As a potential mechanism of enhanced cytolytic function, we analyzed the avidity of binding of the mlNK to NK-resistant tumors (z-Movi).”’ To check out this publication visit our publication webpage here: https://lnkd.in/efaufkMM

Focus on DNA repair! 💡 Did you know? Only through real-time visualization of DNA repair proteins in action, researchers were finally able to solve decade-old questions about the mode of action and order of events in critical DNA repair processes! Here is how: https://lnkd.in/eHXNnTGu

What a success! 100+ participants discussing cutting edge single-molecule biology in Shanghai last weekend. We're already looking forward to the next single-molecule biology symposium! Stay tuned: https://lnkd.in/dqnrMSwG

Dive into the Complex World of Chromatin Replication! Last month we had the honor to have Prof. Nynke Dekker (Oxford, TU Delft) having a webinar with us. Watch it on-demand as she explores the intricate process crucial for genome integrity. Discover how her team uses Dynamic Single-Molecule microscopy to unravel the molecular mechanism of DNA replication. https://lnkd.in/ebY-FMfu

Register now to access our new Webinar by Dr. Sarah Tettamanti, from the Tettamnti foundation in Milan, Italy discussing their groundbreaking research on dual CAR-CIK cells that demonstrated reduced levels of off-target toxicities whilst maintaining high specificity and high avidity for CD123 and CD33 recognition to eliminate acute myeloid leukemia. Register here: https://lnkd.in/dqWcfycW

Interested in understanding the mechanism of action of cell-to-cell binding? Cell Avidity measures the time-sensitive handshake between cells, the critical first minutes of cell-cell binding crucial for function. Cell Avidity sits at the interface between molecular binding and biological outcomes and is a key piece of the puzzle that has been missing from other in vitro technologies. Check out what is avidity and why is it important here: https://bit.ly/3xLKWA8

Groundbreaking study unveils chromatin remodelers' complex behaviors! In a new #eLife publication, researchers from Johns Hopkins University and Howard Hughes Medical Institute have uncovered distinct activities of chromatin remodelers. These key proteins modify chromatin architecture, enabling regulatory proteins to access condensed genomic DNA, thereby controlling gene expression. Employing the advanced dynamic single-molecule tool, C-Trap, the team delivered the first real-time, detailed observations of how these proteins interact with DNA and nucleosomes. This significant discovery enhances our understanding of genome regulation and offers valuable insights for developing therapeutic strategies targeting remodeling pathways. Discover more: https://bit.ly/3Le9q8d

🤖 #ChatGPT just crowned the best dynamic single molecule instrument—but can we really trust #AI bot's taste in lab gear? 🔬 Double-check its pick and explore the C-Trap for yourself here: https://bit.ly/3xHQImg

We are thrilled to announce our brand new Cell Avidity Product Brochure covering the latest publications across cell therapies and immunology that utilize cell avidity to gain unique insights into the mechanism of action. Dive into our brochure to learn how Cell Avidity can help you fully characterize cell binding to discover potency, safety, sensitivity and kinetics of your immunotherapies Download the brochure here: https://bit.ly/3RV1fkG

Exciting News: 80% of the world's top universities in the 2025 rankings are now our partners! 🎓 We're proud to collaborate with these elite institutions, driving innovation together!