Extended Data Fig. 2: Changing balance of BLIMP-1 and BACH2 expression in different B cell states. | Nature Immunology

Extended Data Fig. 2: Changing balance of BLIMP-1 and BACH2 expression in different B cell states.

From: Epigenetic recording of stimulation history reveals BLIMP1–BACH2 balance in determining memory B cell fate upon recall challenge

Extended Data Fig. 2

a-b, Summary data of indicated B cell types from BARBE mice on day 21 (a) or day 28 (b) post NP-KLH immunization. Data were pooled from 3 independent experiments. Each symbol indicates one mouse (n=18 for day 21; n=13 for day 28), and lines denoting means. P-values by two-sided paired student t tests. c-d, MFI summaries of GCs (c) and MBC (d) from BARBE mice on day 14, 21, or 28 post NP-KLH immunization. Representative results of 3 independent experiments are shown. Each symbol indicates one mouse (n=7 for day 14; n=8 for day 21 and day 28), and lines denoting means. P-values by two-sided unpaired student t tests. Related to Fig. 1f–j.

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