Extended Data Fig. 4: Changing balance of BLIMP-1 and BACH2 expression in MBC subsets predisposed for GC or PC development. | Nature Immunology

Extended Data Fig. 4: Changing balance of BLIMP-1 and BACH2 expression in MBC subsets predisposed for GC or PC development.

From: Epigenetic recording of stimulation history reveals BLIMP1–BACH2 balance in determining memory B cell fate upon recall challenge

Extended Data Fig. 4

a-b, MFI summaries of IgM+ and IgG+ MBCs (a) or DN, SP and DP MBCs (b) from BARBE mice on day 14 post NP-KLH immunization. Representative results of 3 independent experiments are shown. Each symbol indicates one mouse (n=10 per group), and lines denote means. P-values by two-sided paired student t tests. Related to Fig. 2. c-f, Summary data of IgM+ and IgG+ MBCs (c-d) or DN, SP and DP MBCs (e-f) from BARBE mice on day 28 post NP-KLH immunization. Representative results of 3 independent experiments are shown. Each symbol indicates one mouse (n=8 per group), and lines denote means. P-values by two-sided paired student t tests.

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