T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors. This disease is most commonly diagnosed in children, where it accounts for ...
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USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most ...
Jul 22, 2024
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The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...
Jul 22, 2024
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Researchers from the University of South Australia have developed a new technique to significantly enhance a powerful treatment for leukemia and other blood cancers.
Jul 19, 2024
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CAR T-cell therapy is an effective treatment for aggressive subtypes of follicular lymphoma, according to a clinical trial published in Nature Medicine.
Jul 18, 2024
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Researchers from the University of Liverpool's Center for Drug Safety Science have identified unpredicted T-cell immune responses to the adenoviral (Oxford/AstraZeneca and Janssen) COVID-19 vaccines, but not to the mRNA vaccines.
Jul 18, 2024
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A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against "inflammaging," which is widely believed to be the root cause of many age-related diseases.
Jul 18, 2024
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There's still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects. While responsible for saving many lives, this treatment sometimes causes cardiac damage that stiffens ...
Jul 17, 2024
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There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully—completely eliminating or greatly reducing cancer in particular patients—other times they don't work at all. It's ...
Jul 15, 2024
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Autoimmune liver diseases (ALDs), including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC), are complex conditions involving the liver's immune-mediated damage. These ...
Jul 15, 2024
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T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.
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