A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led ...
Jul 2, 2024
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As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, ...
Jun 21, 2024
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For the first time, a team co-led by CHU Sainte-Justine researcher and professor in the Faculty of Medicine at Université de Montréal, Alexey Pshezhetsky has succeeded in resolving the unique structure of the HGSNAT enzyme, ...
May 27, 2024
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The structure and functions of the tip of migrating neurons remain elusive. A research group has found that the PTPσ-expressing growth cone senses the extracellular matrix and drives neuronal migration in the injured brain, ...
Mar 11, 2024
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A new editorial paper titled "One more step toward treatment of PARP inhibitor-resistant ovarian cancers" has been published in Oncotarget.
Jan 10, 2024
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A team of researchers led by Rensselaer Polytechnic Institute's Jonathan S. Dordick, Ph.D., Institute Professor of Chemical and Biological Engineering, has illuminated a new possibility for the treatment and prevention of ...
Jul 24, 2023
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Chunyu Wang, Ph.D., professor of biological sciences at Rensselaer Polytechnic Institute, has added to his body of research on Alzheimer's disease with significant findings now published in Angewandte Chemie.
May 24, 2023
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Viruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strains that show attenuated virulence. Such strains may act as vaccines if the attenuated virus can produce immunity ...
Sep 15, 2021
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Amyloid diseases, including Alzheimer's, Parkinson's, type-2 diabetes and other life-threatening diseases, involve pathologic deposits of normally soluble proteins or peptides as insoluble amyloid fibrils. When this happens ...
Jun 28, 2021
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Researchers at the University of Illinois Chicago have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells' innate defense mechanisms.
Mar 15, 2021
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