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Prognostic associations of cortical gyrification in minimally medicated schizophrenia in an early intervention setting
The aberration in cortical gyrification seen in schizophrenia likely originates in the earliest phase of life, as gyrification begins in utero and...
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Brain gyrification in bipolar disorder: a systematic review of neuroimaging studies
Bipolar disorder (BD) is a severe mental illness with a strong genetic component. Genetic variations have been involved in the risk of this disorder,...
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Associations of gestational age with gyrification and neurocognition in healthy adults
Epidemiological studies have shown that gestational age and birth weight are linked to cognitive performance in adults. On a neurobiological level,...
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Cortical morphological changes in multiple sclerosis patients: a study of cortical thickness, sulcal depth, and local gyrification index
PurposeMultiple sclerosis (MS) is a disease that progresses not only with demyelination but also with neurodegeneration. One of the goals of drug...
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Cortical thickness, gyrification and sulcal depth in trigeminal neuralgia
Neuroimaging studies have documented brain structural alterations induced by chronic pain, particularly in gray matter volume. However, the effects...
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Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration
Anomalous patterns of brain gyrification have been reported in major psychiatric disorders, presumably reflecting their neurodevelopmental pathology....
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Reduced cortical gyrification in the posteromedial cortex in unaffected relatives of schizophrenia patients with high genetic loading
Although abnormal cortical gyrification has been consistently reported in patients with schizophrenia, whether gyrification abnormalities reflect a...
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Early alterations of cortical thickness and gyrification in migraine without aura: a retrospective MRI study in pediatric patients
BackgroundMigraine is the most common neurological disease, with high social-economical burden. Although there is growing evidence of brain...
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Human time perspective and its structural associations with voxel-based morphometry and gyrification
Time perspective refers to humans’ concept of integrating and evaluating temporal position and evaluation of memories, emotions, and experiences. We...
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Cortical gyrification and its relationships with molecular measures and cognition in children with the FMR1 premutation
Neurobiological basis for cognitive development and psychiatric conditions remains unexplored in children with the FMR1 premutation (PM). Knock-in...
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Brain structure underlying the empathizing–systemizing difference in children with autism spectrum disorder
BackgroundBehavioral research has shown that children with autism spectrum disorder (ASD) have a higher empathizing–systemizing difference (D score)...
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Daily-Life Negative Affect in Emotional Distress Disorders Associated with Altered Frontoinsular Emotion Regulation Activation and Cortical Gyrification
BackgroundEmotional distress disorders are characterized by high daily-life negative affect and impaired positive reappraisal emotion regulation...
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Early dorsomedial tissue interactions regulate gyrification of distal neocortex
The extent of neocortical gyrification is an important determinant of a species’ cognitive abilities, yet the mechanisms regulating cortical...
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Changed cortical thickness and sulcal depth in pediatric acute lymphoblastic leukemia survivors treated with chemotherapy only
The purpose of this study is to observe the changes of cortical morphological characteristics and their potential contribution to cognitive function...
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Similar cortical morphometry trajectories from 5 to 9 years in children with perinatal HIV who started treatment before age 2 years and uninfected controls
BackgroundLife-long early ART (started before age 2 years), often with periods of treatment interruption, is now the standard of care in pediatric...
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Alterations in cortical morphometry of the contralesional hemisphere in children, adolescents, and young adults with perinatal stroke
Perinatal stroke causes most hemiparetic cerebral palsy and cognitive dysfunction may co-occur. Compensatory developmental changes in the intact...
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Human SERPINA3 induces neocortical folding and improves cognitive ability in mice
Neocortex expansion and folding are related to human intelligence and cognition, but the molecular and cellular mechanisms underlying cortical...
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Structural brain abnormalities and their association with language impairment in school-aged children with Autism Spectrum Disorder
Language impairment is comorbid in most children with Autism Spectrum Disorder (ASD) but its neural basis is poorly understood. Using structural...
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Mechanical hierarchy in the formation and modulation of cortical folding patterns
The important mechanical parameters and their hierarchy in the growth and folding of the human brain have not been thoroughly understood. In this...
