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Gastrointestinal Symptoms in Pediatric Patients with Anxiety Disorders and Their Relationship to Selective Serotonin Reuptake Inhibitor Treatment or Placebo
Gastrointestinal symptoms are commonly reported as adverse effects of selective serotonin reuptake inhibitors (SSRIs), the first-line pharmacologic...
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Serotonin
Serotonin (5-hydroxytryptamine, 5-HT) is acknowledged as a neuromodulator of nervous systems in both invertebrates and vertebrates. It has been... -
Serotonin and emotion regulation: the impact of tryptophan depletion on emotional experience, neural and autonomic activity
The involvement of serotonin in emotion and psychopathology has been extensively examined. Studies using acute tryptophan depletion (ATD) have found...
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Intestinal Predictors of Whole Blood Serotonin Levels in Children With or Without Autism
Hyperserotonemia, or elevated levels of whole blood serotonin (WB5-HT), was the first biomarker linked to autism spectrum disorder (ASD). Despite...
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Prenatal Antidepressant Exposures and Autism Spectrum Disorder or Traits: A Retrospective, Multi-Cohort Study
Prenatal antidepressant exposure has been associated with increased risk for neurodevelopmental disorders in childhood, including autism spectrum...
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Neurobiology of Suicide in Children and Adolescents: Implications for Assessment and Treatment
Pharmacologic and non-pharmacologic treatment of children and adolescents with suicidal thoughts and behavior have lagged behind the already sparse... -
Antidepressants
Depressive symptoms are common co-morbidities of Autism Spectrum Disorder (ASD). However, studies of antidepressants have primarily assessed their... -
Depression and Other Forms of Mental Illness
Major depressive disorder, referred to as depression, is characterized by three principal symptoms: depressed mood, anxiety, and anhedonia. Of these,... -
Prevalence of pediatric acute-onset neuropsychiatric syndrome (PANS) in children and adolescents with eating disorders
BackgroundPediatric obsessive–compulsive disorder (OCD) and eating disorder symptoms frequently overlap, clouding diagnostic certainty and...
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Pharmacological Treatment of Anxiety Disorders in Children and Adolescents
This chapter discusses pharmacological treatment of anxiety disorders in children and adolescents. An overview of psychopharmacological treatments... -
Pharmacological Treatment of Anxiety Disorders: Current and Novel Targets
In this chapter, we are going to focus on the pharmacological treatment of anxiety disorders. In the beginning, we will discuss briefly on... -
Medications to Treat DMDD in Children and Adolescents
Introduced in 2013 as a new diagnosis in the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5), disruptive mood dysregulation... -
Pharmacology for Stress
This chapter addresses psychopharmacology, namely the pharmacology of so-called higher brain functions, with a focus on treatments for conditions... -
Neurochemistry of Childhood Anxiety Disorders
This chapter discusses the general neurochemistry of common childhood anxiety disorders. The chapter starts with a general overview of... -
Treatment of Social Anxiety in Children and Adolescents
This chapter discusses the nature of and treatment for social anxiety disorder. The chapter starts with a discussion of clinical characteristics of... -
Separation Anxiety Disorder in Children and Adolescents
This chapter discusses the nature of and treatment for separation anxiety disorder. The chapter starts with a discussion of clinical characteristics...