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Genetic and Environmental Variation in Continuous Phenotypes in the ABCD Study®
Twin studies yield valuable insights into the sources of variation, covariation and causation in human traits. The ABCD Study® (abcdstudy.org) was...
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A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study
Genetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults....
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Interaction effects of cumulative genetic score and psychological distress on excessive gaming: A 2-year longitudinal study
Biological and psychological factors influence the multifaceted addictive behavior of excessive gaming. While studies have reported the association...
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Are Genetic and Environmental Risk Factors for Psychopathology Amplified in Children with Below-Average Intelligence? A Population-Based Twin Study
There is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this...
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Genotype Data and Derived Genetic Instruments of Adolescent Brain Cognitive Development Study® for Better Understanding of Human Brain Development
The data release of Adolescent Brain Cognitive Development ® (ABCD) Study represents an extensive resource for investigating factors relating to child...
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Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities
Alcohol expectancies (AEs) are associated with likelihood of alcohol initiation and subsequent alcohol use disorders. It is unclear whether genetic...
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Genetic Contributions on Attachment in Emerging Adults: Cumulative Effects of Serotonergic Polymorphisms
Attachment in emerging adults is closely intertwined with emotion regulation, stress coping, and social bonding during the transition from childhood...
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Genetic Engineering
This entry provides an overview of genetic engineering, which is the deliberate modification of the characteristics of a living organism by...
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Using Genomic Structural Equation Modeling to Partition the Genetic Covariance Between Birthweight and Cardiometabolic Risk Factors into Maternal and Offspring Components in the Norwegian HUNT Study
The Barker Hypothesis posits that adverse intrauterine environments result in fetal growth restriction and increased risk of cardiometabolic disease...
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Genetic Engineering
This entry provides an overview of genetic engineering, which is the deliberate modification of the characteristics of a living organism by...
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Characterizing the phenotypic and genetic structure of psychopathology in UK Biobank
Mental health conditions are characterized by higher-order transdiagnostic factor structures, which may contribute to the high levels of comorbidity...
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Impact of a Genetic Diagnosis for a Child’s Autism on Parental Perceptions
Genetic testing is recommended as part of an autism assessment, and most parents support genetic testing for their minor children. However, the...
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Age-Related Variations of Genetic and Environmental Contributions to the Covariation of Fear, Distress and Externalizing Symptoms: A Twin Study in Childhood and Adolescence
The frequency with which Internalizing and Externalizing symptoms co-occur suggests that, behind both domains, there may be a common susceptibility...
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Quantitative behavioral genetic and molecular genetic foundations of the approach and avoidance strategies
Two studies examined genetic and environmental influences on traits proposed by the revised Reinforcement Sensitivity Theory (rRST) of personality....
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Disentangling direct and indirect genetic effects from partners and offspring on maternal depression using trio-GCTA
Maternal depressive symptoms are highly prevalent and can negatively impact affected individuals and family members. Understanding etiological...
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Sex Differences in Autism Symptoms and Mental Health Difficulties in Adolescents with Rare Genetic Disorders
ObjectivesAdolescents with rare genetic disorders often display autism traits and mental health difficulties. Sex differences have been identified...
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Parental Perspectives on Early Life Screening and Genetic Testing for ASD: A Systematic Review
Autism Spectrum Disorder (ASD) is a prevalent neurodevelopmental condition for which no prenatal or early life screening tests exist. Early life...
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Genetic overlap between multivariate measures of human functional brain connectivity and psychiatric disorders
Psychiatric disorders are complex, heritable and highly polygenic. Supported by findings of abnormalities in functional magnetic resonance...
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Factors that Influence Uptake of Genetic Testing for Children with Autism Spectrum Disorder: A Scoping Review
Genetic testing is recommended for all children diagnosed with autism spectrum disorder (ASD), yet available evidence suggests that not all receive...
