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Impact of hepatocyte growth factor on the colonic morphology and gut microbiome in short bowel syndrome rat model
PurposeThis study aimed to investigate the impact of hepatocyte growth factor (HGF) on colonic morphology and gut microbiota in a rat model of short...
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Impact of implementing Dutch versus European guideline risk factor targets in older patients with ischaemic heart disease
BackgroundIn patients with ischaemic heart disease (IHD) aged > 70 years, Dutch and European guidelines recommend different treatment targets:...
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The potential impact of coagulation factor XIII in trauma-induced coagulopathy – a retrospective case series analysis
BackgroundThe role of factor XIII (FXIII) in trauma-induced coagulopathy (TIC) is not fully understood.
MethodsWe evaluated FXIII supplementation in...
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Social differentials in the impact of risk factor exposures on life expectancy and health expectancy
AimThe study estimates the impact of exposure to smoking, high alcohol consumption and obesity on life expectancy and three health expectancy...
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Study results from journals with a higher impact factor are closer to “truth”: a meta-epidemiological study
BackgroundScientists, physicians, and the general public legitimately expect scholarly publications to give true answers to study questions raised....
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Impact of immunohistochemistry staining conditions on the incidence of human epidermal growth factor receptor 2 (HER2)-low breast cancer
We investigated frequencies of HER2-low breast cancer (BC) (immunohistochemistry [IHC] 1+ or 2+ without gene amplification) before and after IHC...
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Therapeutic impact of epidermal growth factor receptor tyrosine kinase inhibitor with various treatment combinations for advanced lung adenocarcinoma
ObjectivesTyrosine kinase inhibitors (TKIs) are the primary therapeutic option for patients with advanced-stage epidermal growth factor...
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Impact of Factor Xa Inhibitor Reversal with Prothrombin Complex Concentrate in Patients with Traumatic Brain Injuries
BackgroundAnticoagulant use prior to trauma has been associated with increased incidence of traumatic brain injury (TBI), intracranial hemorrhage...
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Transcultural adaptation and validation of IMPACT-III and IMPACT-III-P in Spanish families: a multicenter study from SEGHNP
IMPACT-III and IMPACT-III-P are health-related quality of life (HRQoL) questionnaires for patients with pediatric inflammatory bowel disease (p-IBD)...
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Estimating Risk Factor Time Paths Among People with Type 2 Diabetes and QALY Gains from Risk Factor Management
ObjectivesMost type 2 diabetes simulation models utilise equations mapping out lifetime trajectories of risk factors [e.g. glycated haemoglobin (HbA 1c...
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Impact factor JUMPS after the 2020 COVID-19 pandemic: a retrospective study in Dermatology journals
BackgroundThe term “JUMPS” was used to describe the impact factor (IF) in an article published in PubMed in 2021, representing an increase of more...
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Impact of Renal Function on Anti-factor Xa Activity Concentrations with Edoxaban Use in Patients with Non-valvular Atrial Fibrillation
BackgroundChromogenic anti-factor Xa activity (AXA) assay is used to measure the pharmacodynamics of factor Xa inhibitors, including edoxaban....
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The impact of DNA methylation as a factor of Adverse Pregnancy and Birth Outcomes (APBOs): a systematic review protocol
BackgroundDeoxyribonucleic acid (DNA) methylation is one of the epigenetic modifications that has gained a lot of interest as a factor influencing...
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Impact of transforming growth factor beta 1 on normal and thyroid cancer side population cells
PurposeTo determine the impact of exogenous transforming growth factor beta 1 (TGF-β1) on side population (SP) cells isolated from normal, papillary...
