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Prevalence of total joint arthroplasty in the adult spine deformity population
PurposeThe spine, hip, and knee are anatomically and biomechanically connected. Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are...
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Advances in Revision Total Knee Arthroplasty
This book offers a comprehensive guide to revision total knee arthroplasty, a complex surgical procedure with increasing numbers due to the aging...
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Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies
Background and ObjectivesIsavuconazole is a broad-spectrum antifungal agent for the management of invasive fungal disease. Optimised drug exposure is...
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Racial Disparities in Total Knee and Hip Arthroplasty in a Medically Underserved Community with a Diverse Population
IntroductionPrevious studies have demonstrated lower total joint arthroplasty utilization rates and worse postoperative outcomes among non-White...
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Use of Psychoactive Medications and Risk of Suicide in Late Life (75+): A Total Population Study
BackgroundPsychoactive medications play an important role for the mental health and risk of suicidal behaviour in the oldest segment of the...
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Association of total sleep duration variability with risk of new stroke in the middle-aged and elderly Chinese population
ObjectiveTo investigate the association between total sleep duration variability and stroke in the middle-aged and elderly population in China.
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Significant Effects of Renal Function on Mycophenolic Acid Total Clearance in Pediatric Kidney Transplant Recipients with Population Pharmacokinetic Modeling
Background and ObjectivesMycophenolic acid (MPA) is an immunosuppressant commonly prescribed in pediatric kidney transplantation to prevent graft...
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Association between Dietary total antioxidant capacity and knee osteoarthritis: a case-control study in the Iranian Population
AimKnee osteoarthritis (KOA) is a prevalent chronic condition associated with significant pain, disability, and healthcare costs, particularly among...
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Comparison of Racial and Ethnic Mortality Disparities among Post-9/11 Veterans with and without Traumatic Brain Injury to the Total U.S. Adult Population
IntroductionThe extent of racial/ethnic disparities and whether they are attenuated in the Veteran population compared to the total US population is...
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Coronal Plane Alignment Classification of Arthritic Knees in a South Indian Population and Functional Outcome Comparison Post-mechanical Alignment Total Knee Arthroplasty
Study BackgroundMechanical alignment has always been considered as the gold standard in total knee arthroplasty (TKA), but various other coronal...
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Total Hip Arthroplasty in the Paediatric Population—A Systematic Review of Current Outcomes
End-stage hip joint degeneration in the paediatric population is uncommon. Traditionally, arthroplasty has had limited use in this population, owing...
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Childhood sexual abuse is associated with higher total ghrelin serum levels in adulthood: results from a large, population-based study
Ghrelin is an orexigenic peptide hormone synthesized in times of stress and hunger and alterations of the ghrelin system following acute stressors...
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Centenarians: who are they? A description of the total Swedish centenarian population in terms of living arrangements, health, and care utilization
BackgroundThe global centenarian population has doubled each decade and is expected to continue growing. However, information regarding how they...
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Arthroscopy with partial meniscectomy for degenerative tear does not increase the risk of total knee arthroplasty at five year follow up; however, this population undergoes total knee arthroplasty with a lower threshold of osteoarthritis
PurposeDegenerative meniscus tears can cause discomfort in some patients, and when medical treatments fail to provide relief, arthroscopy may be...
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Population Pharmacokinetics of Total Rabbit Anti-thymocyte Globulin in Non-obese Adult Patients Undergoing Hematopoietic Cell Transplantation for Hematologic Malignancy
Background and ObjectivesRabbit anti-thymocyte globulin (rATG), a therapeutic polyclonal antibody against human T cells, is commonly used in...
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Early Results of Bone-Conserving High Flexion Posterior-Stabilized Total Knee System in Indian Population
BackgroundA number of total knee arthroplasty (TKA) systems are used across a variety of markets in which outcome will be influenced by patient...
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Short-stem total hip arthroplasty is equivalent to a standard-length stem procedure in an unselected population at mid-term follow-up
PurposeLimitations of standard-length femoral stems persist, including proximal-distal mismatch, non-ideal load transfer, loss of bone tissue, and...
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The Impact of Biosimilar Use on Total Cost of Care and Provider Financial Performance in the Medicare Oncology Care Model: A Population-Based Simulation Study
IntroductionPayment for oncology care is increasingly moving from fee-for-service to value-based payment (VBP). VBPs are agreements in which...
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Trends of obesity rates between primary total hip arthroplasty patients and the general population from 2013 to 2020
BackgroundThe prevalence of obesity in total hip arthroplasty (THA) patients has been studied in the past. However, there has not been direct...
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Trends in kidney transplantation and living donor nephrectomy in Germany: a total population analysis from 2006 to 2021
PurposeTo analyze recent trends of surgical access routes, length of hospital stay (LOS), and mortality in kidney transplantation (KT) and living...