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Japan’s comprehensive undescended testis screening program: incidence of ascending testis after screening
PurposeScreening for undescended testis (UDT) in Japan is performed as a neonate, then at 1, 3, 10, and 18 months old, and 3 years old. Incidence of...
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The curious case of testicular descent: factors controlling testicular descent with a note on cryptorchidism
BackgroundThe testicular descent is a uniquely complex process depending upon multiple factors like growth and reorganisation of the specific gonadal...
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A comparative study of smooth muscle cell characteristics and myofibroblasts in processus vaginalis of pediatric inguinal hernia, hydrocele and undescended testis
BackgroundCongenital inguinal hernia, hydrocele and undescended testis (UDT) are associated with patent processus vaginalis. The smooth muscles...
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Orchidopexy for undescended testis—rate and predictors of re-ascent
PurposeThis study aimed to investigate the rate of re-ascent requiring re-operation after primary orchidopexy and to investigate eventual differences...
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Hiding testis fused with liver, an unusual diagnostic challenge!
IntroductionSplenogonadal and adrenogonadal fusion have been incriminated as causes in some cases of cryptorchidism, but hepato-testicular fusion is...
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Myoid gonadal stromal tumor of the testis—the novel subtype of testicular gonadal stromal tumors: a case report and review of the literature
BackgroundSex cord gonadal stromal tumors compose less than 10% of all testicular neoplasms and consist of a variety of histological subtypes. In...
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Testicular descent revisited: a micro-computed tomography study in fetal rats
PurposeThere is a long history of research dealing with the embryology of the testicular descent. However, important aspects like the role of the...
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The undescended testis in children and adolescents part 2: evaluation and therapeutic approach
Undescended testis (UDT) is defined as failure of a testis to descend into the scrotum and it is a common reason for consultation in pediatric...
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The role of the resistive index in predicting testicular atrophy after orchiopexy in unilateral undescended testis
PurposeOne of the most important complications of undescended testis (UDT) surgery is testicular atrophy (TA). We aimed to investigate the factors...
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The undescended testis in children and adolescents. Part 1: pathophysiology, classification, and fertility- and cancer-related controversies
Undescended testis (UDT) is defined as failure of a testis to descend into the scrotum. It is one of the most common reasons for consultation in...
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Management of high inguinal undescended testis: a review of literature
BackgroundUndescended testis is one of the most common paediatric surgical diagnoses. A lot of research has been done to date, to standardise the...
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Analysis of factors associated with undescended testis in patients with congenital diaphragmatic hernia
PurposeThis study aimed to investigate the incidence and clinical factors associated with undescended testes (UDT) in patients with congenital...
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Identification of a window of androgen sensitivity for somatic cell function in human fetal testis cultured ex vivo
BackgroundReduced androgen action during early fetal development has been suggested as the origin of reproductive disorders comprised within the...
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BDNF is upregulated by androgen in the inguinal fat pad of immature mice and may regulate inguinoscrotal testicular descent
BackgroundAndrogens control rodent inguinoscrotal testicular descent during a “programming window” (E12–17). It is proposed that androgen...
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Ectopic testis: an experience of a tertiary-level urology center at Upper Egypt
BackgroundTesticular ectopia is defined as a testis which is located away from the normal pathway of testicular descent and outside its ipsilateral...
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GWAS in people of Middle Eastern descent reveals a locus protective of kidney function—a cross-sectional study
BackgroundType 2 diabetes is one of the leading causes of chronic kidney failure, which increases globally and represents a significant threat to...
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Testicular torsion: its effect on autoimmunisation, pituitary–testis axis and correlation with primary gonadal dysfunction in boys
BackgroundTorsion of the testis is an urgent surgical condition that endangers the viability of the gonad and the fertility of the patient. Our aim...
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Abnormal histology in testis from prepubertal boys with monorchidism
BackgroundLittle is known about the histology of contralateral descended testes in boys with unilaterally absent testis. We investigated whether...
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Maldescensus testis – Epidemiologische Übersichtsarbeit hinsichtlich Pathophysiologie, Diagnostik und leitliniengerechter Therapiemaßnahmen
Cryptorchidism is one of the most frequent congenital anomalies in boys. Multiple factors influence the physiological descent of testes, including...
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Effect of adjunctive hormonal therapy on testicular descent and spermatogenic function among children with cryptorchidism: a systematic review and meta-analysis
ObjectivesTo systematically evaluate the effect of adjunctive hormonal therapy on testicular descent and spermatogenic function among children with...