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Neural correlates of digital measures shown by structural MRI: a post-hoc analysis of a smartphone-based remote assessment feasibility study in multiple sclerosis
BackgroundA study was undertaken to evaluate remote monitoring via smartphone sensor-based tests in people with multiple sclerosis (PwMS). This...
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The association between white matter tract structural connectivity and information processing speed in relapsing-remitting multiple sclerosis
BackgroundInformation processing speed (IPS) deterioration is common in relapsing-remitting multiple sclerosis (RRMS) patients [
1 ] and might... -
Individual reserve in aging and neurological disease
Background and objectiveCognitive and physical functions correlate and delineate aging and disease trajectories. Whereas cognitive reserve (CR) is...
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Correction to: Improvements in Cognitive Processing Speed, Disability, and Patient‑Reported Outcomes in Patients with Early Relapsing‑Remitting Multiple Sclerosis Treated with Natalizumab: Results of a 4‑year, Real‑World, Open‑Label Study
BackgroundSTRIVE was a prospective, 4-year, multicenter, observational, open-label, single-arm study of natalizumab treatment in anti-JC virus...
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Cognitive impairment and health-related quality of life amongst older Australians: evidence from a longitudinal investigation
IntroductionAustralia’s population is steadily growing older, with older persons expected to make up over 20% of the population by 2066. Ageing is...
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Improvements in Cognitive Processing Speed, Disability, and Patient-Reported Outcomes in Patients with Early Relapsing-Remitting Multiple Sclerosis Treated with Natalizumab: Results of a 4-year, Real-World, Open-Label Study
BackgroundSTRIVE was a prospective, 4-year, multicenter, observational, open-label, single-arm study of natalizumab treatment in anti-JC virus...
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The influence of adiposity on the interactions between strength, physical function and cognition among older adults in the Australian Diabetes, Obesity and Lifestyle (AusDiab) study
BackgroundBeing overweight or obese may be associated with lower physical and cognitive function, but in late-adulthood (≥ 65 years) evidence is...
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Benefits of Treatment with Ginkgo Biloba Extract EGb 761 Alone or Combined with Acetylcholinesterase Inhibitors in Vascular Dementia
BackgroundVascular dementia (VaD) is the most severe manifestation of cognitive impairment caused by cerebrovascular disease. There are currently no...
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Sex differences in brain atrophy and cognitive impairment in Parkinson’s disease patients with and without probable rapid eye movement sleep behavior disorder
BackgroundThe presence of rapid eye movement sleep behavior disorder (RBD) contributes to increase cognitive impairment and brain atrophy in...
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Neurocognitive function as outcome and predictor for prefrontal transcranial direct current stimulation in major depressive disorder: an analysis from the DepressionDC trial
Transcranial direct current stimulation (tDCS) of the prefrontal cortex might beneficially influence neurocognitive dysfunctions associated with...
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The brief repeatable battery of neuropsychological tests (BRB-N) version a: update of Italian normative data from the Italian Neuroimaging Network Initiative (INNI)
BackgroundCognitive impairment is a common clinical manifestation in people with multiple sclerosis (PwMS) and significantly impacts patients'...
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Effects of motor imagery based brain-computer interface on upper limb function and attention in stroke patients with hemiplegia: a randomized controlled trial
BackgroundSeeking positive and comprehensive rehabilitation methods after stroke is an urgent problem to be solved, which is very important to...
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Cognitive dysfunction in diabetes-related foot complications: A cohort study
ObjectiveMild-moderate cognitive impairment has been identified in general diabetes, and early evidence indicates cognitive reductions may be more...
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Don’t be late! Timely identification of cognitive impairment in people with multiple sclerosis: a study protocol
BackgroundCognitive impairment occurs in up to 65% of people with multiple sclerosis (PwMS), negatively affecting daily functioning and...
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Serum albumin and white matter hyperintensities
People living with HIV and those diagnosed with alcohol use disorders (AUD) relative to healthy individuals commonly have low levels of serum...
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Validity of the Italian multiple sclerosis neuropsychological screening questionnaire
The Multiple Sclerosis Neuropsychological Questionnaire (MSNQ) is a brief questionnaire useful for screening patients with multiple sclerosis (MS) at...
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The relationship between cognition, depression, fatigue, and disability in patients with multiple sclerosis
BackgroundMultiple sclerosis (MS) is a chronic, progressive, and neurodegenerative central nervous system disorder. MS usually causes disability,...
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Feasibility and preliminary efficacy of different intensities of functional training in elderly type 2 diabetes patients with cognitive impairment: a pilot randomised controlled trial
BackgroundAging and type-2 diabetes (T2D) are the most important risk factors for cognitive impairment and Alzheimer’s disease. Exercise training is...
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Potential cognitive and neural benefits of a computerised cognitive training programme based on Structure Learning in healthy adults: study protocol for a randomised controlled trial
BackgroundCognitive flexibility refers to the capacity to shift between conceptual representations particularly in response to changes in instruction...
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Brain-cognition relationships in late-life depression: a systematic review of structural magnetic resonance imaging studies
BackgroundMost patients with late-life depression (LLD) have cognitive impairment, and at least one-third meet diagnostic criteria for mild cognitive...