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Sleep spindles are reduced in children with Down syndrome and sleep-disordered breathing
BackgroundChildren with Down syndrome (DS) are at increased risk of sleep-disordered breathing (SDB). We investigated sleep spindle activity, as a...
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Sleep spindles in people with schizophrenia, schizoaffective disorders or bipolar disorders: a pilot study in a general population-based cohort
BackgroundSleep spindles have been involved in sleep stabilization and sleep-related memory mechanisms and their deficit emerged as possible...
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A Thalamocortical Perspective on Sleep Spindle Alterations in Neurodevelopmental Disorders
Purpose of ReviewNeurodevelopmental disorders are a group of conditions that affect the development and function of the nervous system, typically...
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Electrophysiological Mechanisms of Memory Consolidation in Human Non-rapid Eye Movement Sleep
Purpose of ReviewPioneering work in rodents has shown that the reactivation of recently acquired memories during sleep is a key mechanism underlying...
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Cortical signatures of sleep are altered following effective deep brain stimulation for depression
Deep brain stimulation (DBS) of the subcallosal cingulate cortex (SCC) is an experimental therapy for treatment-resistant depression (TRD). Chronic...
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Sleep spindle architecture associated with distinct clinical phenotypes in older adults at risk for dementia
Sleep spindles are a hallmark of non-REM sleep and play a fundamental role in memory consolidation. Alterations in these spindles are emerging as...
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An examination of sleep spindle metrics in the Sleep Heart Health Study: superiority of automated spindle detection over total sigma power in assessing age-related spindle decline
BackgroundSleep spindle activity is commonly estimated by measuring sigma power during stage 2 non-rapid eye movement (NREM2) sleep. However,...
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The importance of sleep for the developing brain
Purpose of reviewThis paper summarizes recent research regarding the possible contribution of sleep to brain development. Major milestones in brain...
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Surgical treatment for obstructive sleep apnea: effect on sleep architecture
PurposeInvestigate the effect of surgical treatment of obstructive sleep apnea syndrome (OSA) on sleep architecture.
MethodsObservational...
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The Impact of Vestibular Stimulation on Sleep and Respiration in Humans
Purpose of ReviewThe vestibular system plays a role in both sleep and circadian rhythm regulation. Therefore, it has become a target for those...
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Sleep as a driver of pre- and postnatal brain development
AbstractIn 1966, Howard Roffwarg proposed the ontogenic sleep hypothesis, relating neural plasticity and development to rapid eye movement (REM)...
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The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia: a randomized clinical trial
Sleep spindles, defining oscillations of stage 2 non-rapid eye movement sleep (N2), mediate memory consolidation. Schizophrenia is characterized by...
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Sleep in 22q11.2 Deletion Syndrome: Current Findings, Challenges, and Future Directions
Purpose of ReviewTo summarize current literature available on sleep in 22q11.2 Deletion Syndrome (22q11.2DS; Velocardiofacial or DiGeorge Syndrome),...
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Sleep in Alzheimer’s disease: a systematic review and meta-analysis of polysomnographic findings
Polysomnography (PSG) studies of sleep changes in Alzheimer’s disease (AD) have reported but not fully established the relationship between sleep...
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Polysomnographic Predictors of Sleep, Motor, and Cognitive Dysfunction Progression in Parkinson’s Disease
Purpose of ReviewSleep disturbances are an important nonmotor feature of Parkinson’s disease (PD) that can cause polysomnographic (PSG) alterations....
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The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep
Benzodiazepines and ‘Z-drugs’ (including zolpidem and zopiclone) are GABA A receptor (GABA A R) positive modulators commonly prescribed as hypnotics to...
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Sleep and Autobiographical Memory
Purpose of ReviewSleep is important for memory consolidation in laboratory-based stimuli, but less is known about how sleep impacts autobiographical...
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Sleep Duration and Executive Function in Adults
Purpose of ReviewTo review the literature examining the relationship between sleep and cognition, specifically examining the sub-domain of executive...
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Sleep-Related Changes Prior to Cognitive Dysfunction
Purpose of ReviewThe aim of this review is to summarize the current evidence on the relationship between sleep and cognition and present available...
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Neurostimulation and sleep in patients with epilepsy—English version
BackgroundChronic sleep disturbance may affect seizure frequency and efficacy of treatment in epilepsy patients. Vagus nerve stimulation (VNS) and...
