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Reirradiation for diffuse intrinsic pontine glioma: prognostic radiomic factors at progression
PurposeDiffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain tumor. Radiation therapy (RT) is the standard treatment, with...
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Prospective randomized clinical studies involving reirradiation: update of a systematic review
BackgroundReirradiation is a potentially useful option for many patients with recurrent cancer, aiming at cure or symptom palliation, depending on...
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Post-mastectomy reirradiation for ipsilateral T3N0M0 breast tumor relapse: a population-based study
IntroductionPost-mastectomy radiotherapy is commonly recommended for T3N0M0 breast cancer, particularly in the presence of adverse prognostic...
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The evolving role of reirradiation in the management of recurrent brain tumors
Despite aggressive management consisting of surgery, radiation therapy (RT), and systemic therapy given alone or in combination, a significant...
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Linac-based stereotactic salvage reirradiation for intraprostatic prostate cancer recurrence: toxicity and outcomes
BackgroundThe rates of local failure after curative radiotherapy for prostate cancer (PC) remain high despite more accurate locoregional treatments...
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Reirradiation on spine metastases: an Italian survey on behalf of palliative care and reirradiation study groups of Italian association of radiotherapy and clinical oncology (AIRO)
AimThis survey derived from the collaboration between the Palliative Care and Reirradiation Study Groups of the Italian Association of Radiotherapy...
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Reirradiation with radiosurgery or stereotactic fractionated radiotherapy in association with regorafenib in recurrent glioblastoma
PurposeNo standard treatment has yet been established for recurrent glioblastoma (GBM). In this context, the aim of the current study was to evaluate...
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Early effectiveness and toxicity outcomes of reirradiation after breast conserving surgery for recurrent or new primary breast cancer
PurposeBreast reirradiation (reRT) after breast conserving surgery (BCS) has emerged as a viable alternative to mastectomy for women presenting with...
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Reirradiation versus systemic therapy versus combination therapy for recurrent high-grade glioma: a systematic review and meta-analysis of survival and toxicity
PurposeThis review compares reirradiation (reRT), systemic therapy and combination therapy (reRT & systemic therapy) with regards to overall survival...
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Lomustine with or without reirradiation for first progression of glioblastoma, LEGATO, EORTC-2227-BTG: study protocol for a randomized phase III study
BackgroundChemotherapy with lomustine is widely considered as standard treatment option for progressive glioblastoma. The value of adding...
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Comparison of carbon ion and photon reirradiation for recurrent glioblastoma
PurposePurpose of this study was to investigate overall survival in recurrent glioblastoma treated with either carbon ion reirradiation or photon...
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Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence
Recurrent and second primary head and neck cancers represent a clinical challenge due to frequently unresectable and/or locally advanced disease....
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Reirradiation of head and neck squamous cell carcinomas: a pragmatic approach, part II: radiation technique and fractionations
IntroductionReirradiation (reRT) of local recurrent/second primary tumors of the head and neck represents a potential curative treatment for patients...
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Reirradiation of head and neck squamous cell carcinomas: a pragmatic approach—part I: prognostic factors and indications to treatment
IntroductionReirradiation (reRT) of locally recurrent/second primary tumors of the head and neck region is a potentially curative treatment for...
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Predictors of toxicity after curative reirradiation with intensity modulated radiotherapy or proton therapy for recurrent head and neck carcinoma: new dose constraints for pharyngeal constrictors muscles and oral cavity
BackgroundOur study aims to identify predictive factors of moderate to severe (grade ≥ 2) late toxicity after reirradiation (reRT) of recurrent head...
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Optimizing reirradiation for relapsed medulloblastoma: identifying the ideal patient and tumor profiles
BackgroundFirst-line therapies for medulloblastoma(MBL) are obtaining higher survival-rates while decreasing late-effects, but treatment at relapse...
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How ten-years of reirradiation for paediatric high-grade glioma may shed light on first line treatment
PurposeRecurrence incidence for paediatric/adolescent high-grade glioma (HGG) exceeds 80%. Reirradiation (reRT) palliates symptoms and delays further...
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Stereotactic Body Radiation Therapy in Recurrent Head and Neck Cancer: Where Do We Stand?
This review explores the difficulties encountered in the management of head and neck cancer (HNC), with special attention to the challenges presented...
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Pilot Evaluation of Perioperative High Dose Rate Brachytherapy in Head Neck Cancers
Perioperative high dose rate brachytherapy involves insertion of brachytherapy catheter over the tumor bed during surgical removal of disease...
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Reirradiation salvage radiotherapy for recurrent prostate cancer after primary low-dose brachytherapy
PurposeLocal recurrence of prostate cancer after low-dose rate brachytherapy is a clinical problem with limited salvage treatment options. This...