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Modifiable Risk Factors for Accelerated Decline in Processing Speed: Results from Three Dutch Population Cohorts
BackgroundSeveral lifestyle, cardiovascular and psychosocial factors are associated with risk of cognitive decline and dementia. We studied the...
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The interplay between polygenic score for tumor necrosis factor-α, brain structural connectivity, and processing speed in major depression
Reduced processing speed is a core deficit in major depressive disorder (MDD) and has been linked to altered structural brain network connectivity....
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Evaluation of a self-administered iPad®-based processing speed assessment for people with multiple sclerosis in a clinical routine setting
BackgroundLimited resources often hinder regular cognitive assessment of people with multiple sclerosis (pwMS) in standard clinical care. A...
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Perceived but not objective measures of neighborhood safety and food environments are associated with longitudinal changes in processing speed among urban older adults
BackgroundAlthough a growing body of literature documents the importance of neighborhood effects on late-life cognition, little is known about the...
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The efficacy of speed of processing training for improving processing speed in individuals with multiple sclerosis: a randomized clinical trial
ObjectiveThe current study examines the efficacy of speed of processing training (SOPT) to improve processing speed (PS) in individuals with multiple...
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Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms
The DDR1 locus is associated with the diagnosis of schizophrenia and with processing speed in patients with schizophrenia and first-episode...
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Cognitive reserve, depressive symptoms, obesity, and change in employment status predict mental processing speed and executive function after COVID-19
The risk factors for post-COVID-19 cognitive impairment have been poorly described. This study aimed to identify the sociodemographic, clinical, and...
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A hypoarousal model of neurological post-COVID syndrome: the relation between mental fatigue, the level of central nervous activation and cognitive processing speed
BackgroundKnowledge on the nature of post-COVID neurological sequelae often manifesting as cognitive dysfunction and fatigue is still unsatisfactory.
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CCRT and aerobic exercise: a randomised controlled study of processing speed, cognitive flexibility, and serum BDNF expression in schizophrenia
Computerised cognitive remediation therapy (CCRT) and aerobic exercise are often used to rehabilitate social functioning in patients with...
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Solution Focused vs Problem Focused Questions on Affect and Processing Speed among Individuals with Depression
The present study investigated the effect of solution-focused and problem-focused questions on affect and processing speed in a sample of 60...
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Virtual reality as a method of cognitive training of processing speed, working memory, and sustained attention in persons with acquired brain injury: a protocol for a randomized controlled trial
BackgroundAcquired brain injury (ABI) often leads to persisting somatic, cognitive, and social impairments. Cognitive impairments of processing...
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The association between white matter tract structural connectivity and information processing speed in relapsing-remitting multiple sclerosis
BackgroundInformation processing speed (IPS) deterioration is common in relapsing-remitting multiple sclerosis (RRMS) patients [
1 ] and might... -
Thalamic atrophy moderates associations among aerobic fitness, cognitive processing speed, and walking endurance in persons with multiple sclerosis
Background and objectivesThalamic atrophy (TA) represents a biomarker of neurodegeneration and associated dysfunction/decline in physical and...
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The influence of walking speed and effects of signal processing methods on the level of human gait regularity during treadmill walking
BackgroundIn recent years the use of sample entropy (SampEn) to evaluate the complexity of the locomotor system in human gait data has gained in...
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Correction to: Improvements in Cognitive Processing Speed, Disability, and Patient‑Reported Outcomes in Patients with Early Relapsing‑Remitting Multiple Sclerosis Treated with Natalizumab: Results of a 4‑year, Real‑World, Open‑Label Study
BackgroundSTRIVE was a prospective, 4-year, multicenter, observational, open-label, single-arm study of natalizumab treatment in anti-JC virus...
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Association of low-frequency and rare coding variants with information processing speed
Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as...
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Processing speed dysfunction is associated with functional corticostriatal circuit alterations in childhood epilepsy with centrotemporal spikes: a PET and fMRI study
PurposeEpilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children and usually presents with cognitive dysfunctions....
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Profiling cognitive–motor interference in a large sample of persons with progressive multiple sclerosis and impaired processing speed: results from the CogEx study
BackgroundPerforming cognitive–motor dual tasks (DTs) may result in reduced walking speed and cognitive performance. The effect in persons with...
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Improvements in Cognitive Processing Speed, Disability, and Patient-Reported Outcomes in Patients with Early Relapsing-Remitting Multiple Sclerosis Treated with Natalizumab: Results of a 4-year, Real-World, Open-Label Study
BackgroundSTRIVE was a prospective, 4-year, multicenter, observational, open-label, single-arm study of natalizumab treatment in anti-JC virus...
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Processing speed is affected by early impairment in kidney function in the general elder population
BackgroundChronic kidney disease, cardiovascular disease, and cognitive dysfunction are common in the elder population. There is evidence of a...