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Sleep and Perivascular Spaces
Purpose of ReviewThe glymphatic system is hypothesized to act as the brain’s filtration system to remove toxic solutes that accumulate throughout the...
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Meta-analysis of the relationship between the number and location of perivascular spaces in the brain and cognitive function
BackgroundCerebral perivascular spaces are part of the cerebral microvascular structure and play a role in lymphatic drainage and the removal of...
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Glymphatic system impairment in Alzheimer’s disease: associations with perivascular space volume and cognitive function
ObjectivesTo investigate glymphatic function in Alzheimer’s disease (AD) using the diffusion tensor image analysis along the perivascular space...
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Impaired glymphatic drainage underlying obstructive sleep apnea is associated with cognitive dysfunction
Obstructive sleep apnea (OSA) is highly prevalent but easily undiagnosed and is an independent risk factor for cognitive impairment. However, it...
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Dilated perivascular spaces and steno-occlusive changes in children and adults with moyamoya disease
BackgroundDilated perivascular spaces (DPVS), known as one of imaging markers in cerebral small vessel disease, may be found in patients with...
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Increased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space
BackgroundPreliminary evidence suggests that several headache disorders may be associated with glymphatic dysfunction. However, no studies have been...
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Transurethral en bloc resection of a bladder perivascular epithelioid cell tumor (PEComa): a case report
BackgroundPerivascular epithelioid cell tumor (PEComa) is a mesenchymal tumor with distinct histologic and immunologic features. PEComas that...
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Homocysteine is related to enlarged perivascular spaces in the brainstem in patients with isolated pontine infarction
BackgroundHomocysteine is correlated with several imaging features of cerebral small vessel disease including white matter hyperintensities, lacunes,...
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Aggravation of Enlarged Perivascular Spaces in the Centrum Semiovale of Patients with Aneurysmal Subarachnoid Hemorrhage
PurposeThis study aimed to investigate whether enlarged perivascular spaces (ePVS) within the basal ganglia (BG) or centrum semiovale (CSO) aggravate...
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Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex
Perivascular spaces (PVS) are compartments surrounding cerebral blood vessels that become visible on MRI when enlarged. Enlarged PVS (EPVS) are...
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MRI-visible enlarged perivascular spaces: imaging marker to predict cognitive impairment in older chronic insomnia patients
ObjectivePerivascular spaces (PVS), components of the glymphatic system in the brain, have been known to be important conduits for clearing metabolic...
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Perivascular spaces and brain waste clearance systems: relevance for neurodegenerative and cerebrovascular pathology
Perivascular spaces (PVS) of the brain, often called Virchow-Robin spaces, comprise fluid, cells and connective tissue, and are externally limited by...
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Diffusion-weighted image analysis along the perivascular space (DWI–ALPS) for evaluating interstitial fluid status: age dependence in normal subjects
PurposeThe purpose of this study was to evaluate the interstitial fluid status in a wide range of age groups using diffusion-weighted image analysis...
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Chinese Herbal Medicine Adjusting Brain Microenvironment via Mediating Central Nervous System Lymphatic Drainage in Alzheimer’s Disease
Due to its complex pathogenesis and lack of effective therapeutic methods, Alzheimer’s disease (AD) has become a severe public health problem...
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MRI-visible perivascular spaces as an imaging biomarker in Fabry disease
IntroductionFabry disease (FD) is an X-linked lysosomal storage disorder resulting in vascular glycosphingolipid accumulation and increased stroke...
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Requirement of brain interleukin33 for aquaporin4 expression in astrocytes and glymphatic drainage of abnormal tau
Defective aquaporin4 (AQP4)-mediated glymphatic drainage has been linked to tauopathy and amyloid plaque in Alzheimer’s disease. We now show that...
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Does Impaired Glymphatic Drainage Cause Glymphedema? A Review Tailored to Neurocritical Care and Neurosurgery
Research into the glymphatic system reached an inflection point with steep trajectory in 2012 when it was formally recognized and named, but the...
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The application analysis of 8F ultrafine chest drainage tube for thoracoscopic lobectomy of lung cancer
BackgroundCurrently, thoracoscopic lobectomy is widely used in clinical practice, and postoperative placement of ultrafine drainage tube has...
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Small single perivascular hepatocellular carcinoma: comparisons of radiofrequency ablation and microwave ablation by using propensity score analysis
ObjectivesWe aimed to compare the therapeutic outcomes of radiofrequency ablation (RFA) and microwave ablation (MWA) as first-line therapies in...