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Strategies Used to Manage Chronic Pain in HIV-Disease: Comparing Persons Prescribed Opioids Versus Persons not Receiving Opioids
Chronic pain is common in people living with HIV (PLWH), causes substantial disability and is associated with limitations in daily activities....
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Patterns of polydrug use among Black Americans who misuse opioids
In the United States, opioid-related deaths involving polydrug use are now more prevalent than those involving only opioids. What often goes...
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Patient Perceptions of Opioids and Benzodiazepines and Attitudes Toward Deprescribing
BackgroundOpioids and benzodiazepines (BZDs) pose a public health problem. Older adults are especially susceptible to adverse events from opioids and...
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New Synthetic Opioids: Clinical Considerations and Dangers
Since the early 2010s, synthetic opioids have significantly contributed to overall opioid-related overdose mortalities. For point of reference, of...
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Opioids for Acute Musculoskeletal Pain: A Systematic Review with Meta-Analysis
ObjectiveTo evaluate the efficacy of opioids for people with acute musculoskeletal pain against placebo.
Study DesignSystematic review and...
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Adverse Drug Reactions to Opioids: A Study in a National Pharmacovigilance Database
IntroductionOpioids are commonly used as analgesics; however, like any medicine, they can produce adverse drug reactions (ADRs), including nausea,...
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Use of prescription opioids in Israel and socio-economic correlations between 2010 and 2020
BackgroundThe use of opioids has increased dramatically over the past several years in Israel. The aim of this study was to explore the trends of...
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Risk of Mortality Associated with Potentially Inappropriate Medication Use Including Opioids in Older Adults
Introduction and ObjectiveAs the population ages, understanding the potential risks associated with inappropriate medication use becomes increasingly...
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Unveiling the link between chronic pain and misuse of opioids and cannabis
Over 50 million Americans endure chronic pain where many do not receive adequate treatment and self-medicate to manage their pain by taking...
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Effects of Opioids on Immune and Endocrine Function in Patients with Cancer Pain
Opioids are an important treatment in managing cancer pain. Uncontrolled pain can be detrimental to function and quality of life. Common adverse...
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Quality-of-Life Outcomes for Patients Taking Opioids and Psychotropic Medications Before Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
BackgroundThe impact of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) on quality of life (QoL) for patients taking...
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Health care system costs related to potentially inappropriate medication use involving opioids in older adults in Canada
BackgroundOlder adults are at risk of potentially inappropriate medication use given polypharmacy, multimorbidity, and age-related changes, which...
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Counseling for opioids prescribed at discharge of hospitalized adolescent trauma patients
BackgroundExpert consensus recommends prescription opioid safety counseling be provided when prescribing an opioid. This may be especially important...
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Opioids for the management of dyspnea in cancer patients: a systematic review and meta-analysis
Dyspnea is a prevalent symptom that significantly reduces quality of life of cancer patients. Palliative treatment is necessary when the symptoms do...
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Prescription and consumption of opioids after bariatric surgery: a multicenter prospective cohort study
IntroductionIn the current opioid crisis, bariatric surgical patients are at increased risk of harms related to postoperative opioid overprescribing....
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Recent trends in the prescription of opioids in the emergency department in patients with urolithiasis
PurposePain management is central in the treatment of urolithiasis. We aimed to estimate the impact of the 2017 Department of Health and Human...
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Unmet needs and harm reduction preferences of syringe services program participants: differences by co-use of illicit opioids and methamphetamine
BackgroundThe current fourth wave of the United States opioid overdose epidemic is characterized by the co-use of opioids and stimulants, including...
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Reported adverse events related to use of hepatitis C virus direct-acting antivirals with opioids: 2017–2021
IntroductionDue to concerns over potential interactions between some hepatitis C direct-acting antivirals (DAAs) and opioids, we describe adverse...
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Opioids and Chronic Pain: Impact of the NIH Pathways to Prevention Evidence-Based Workshop Program
The National Institutes of Health (NIH) Office of Disease Prevention (ODP) sponsors Pathways to Prevention (P2P), an evidence-based scientific...
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Effect of surgery on the long-term use of opioids in patients with degenerative back disorders: a retrospective register-based study
PurposeThis study based exclusively on register-data provides a scientific basis for further research on the use of opioids in patients with...