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Integrative bioinformatics analysis to identify ferroptosis-related genes in non-obstructive azoospermia
PurposeThe objective of this study was to discern ferroptosis-related genes (FRGs) linked to non-obstructive azoospermia and investigate the...
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Testicular sperm aspiration (TESA) outcome in Middle Eastern patients with non-obstructive azoospermia: a retrospective cohort study
BackgroundInfertility is an important health problem, affecting couples worldwide. Non-obstructive azoospermia is the most severe form of...
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Cell-Based Therapy Approaches in Treatment of Non-obstructive Azoospermia
The rate of infertility has globally increased in recent years for a variety of reasons. One of the main causes of infertility in men is azoospermia...
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Y chromosome polymorphisms contribute to an increased risk of non-obstructive azoospermia: a retrospective study of 32,055 Chinese men
PurposeTo investigate the prevalence of Y chromosome polymorphisms in Chinese men and analyze their associations with male infertility and female...
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Molecular mechanisms of cellular dysfunction in testes from men with non-obstructive azoospermia
Male factor infertility affects 50% of infertile couples worldwide; the most severe form, non-obstructive azoospermia (NOA), affects 10–15% of...
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IVF outcomes following ICSI cycles using testicular sperm in obstructive (OA) vs. non-obstructive azoospermia (NOA) and the impact of maternal and paternal age: a SART CORS data registry
PurposeTo assess the differences in IVF outcomes between couples with obstructive azoospermia (OA), non-obstructive azoospermia (NOA), and male...
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A novel splicing mutation in helicase for meiosis 1 leads to non-obstructive azoospermia
PurposeNon-obstructive azoospermia (NOA) is an essential cause of male infertility for which treatment options are limited. The pathogenic mechanism...
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Constructing a seventeen-gene signature model for non-obstructive azoospermia based on integrated transcriptome analyses and WGCNA
BackgroundNon-obstructive azoospermia (NOA) affects approximately 1% of the male population worldwide. The underlying mechanism and gene...
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Testicular piRNA Analysis Identified Dysregulated piRNAs in Non-obstructive Azoospermia
Male infertility has remained idiopathic in a remarkable proportion of all cases. Gonadal expression of PIWI-interacting RNAs (piRNAs) has been shown...
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A Prediction Model of Sperm Retrieval in Males with Idiopathic Non-obstructive Azoospermia for Microdissection Testicular Sperm Extraction
Patients with Idiopathic non-obstructive azoospermia (iNOA) can achieve fertility by extracting testicular sperm through microdissection testicular...
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Comparison of unilateral and bilateral microdissection testicular sperm extraction (MD-TESE) in patients with non-obstructive azoospermia: a prospective study
ObjectiveTo compare sperm retrieval rates between unilateral and bilateral microdissection testicular sperm extraction (MD-TESE) procedures in...
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Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia
BackgroundThere is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from...
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A novel ADGRG2 truncating variant associated with X-linked obstructive azoospermia in a large Chinese pedigree
PurposeIn this study, we aimed to identify sterility-related variants in a Chinese pedigree with male infertility and to reveal the different...
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An overview of CFTR mutation profiles and assisted reproductive technology outcomes in Chinese patients with congenital obstructive azoospermia
PurposeThe cystic fibrosis transmembrane conductance regulator (CFTR) is the most common causative gene attributed to congenital obstructive...
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Predicting the testicular function in non-obstructive azoospermia via targeted gene panel
BackgroundMen with non-obstructive azoospermia constitute a challenging subgroup of male infertility patients in whom a genetic cause of defective...
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Non-obstructive idiopathic azoospermia vs azoospermia with antecedents of cryptorchidism: ways and probabilities of becoming parents
BackgroundNon-obstructive azoospermia (NOA) with history of cryptorchidism and idiopathic NOA are the most common forms of NOA without genetic...
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Gonadotropins treatment prior to microdissection testicular sperm extraction in non-obstructive azoospermia: a single-center cohort study
BackgroundMicrodissection testicular sperm extraction (micro-TESE) in combination with ICSI can make paternity possible for non-obstructive...
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Cryopreserved testicular spermatozoa among patients with azoospermia
PurposeTo investigate cryopreserved testicular spermatozoa among patients with azoospermia.
MethodsIn this retrospective study spanning from October...
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A 3-Gene Random Forest Model to Diagnose Non-obstructive Azoospermia Based on Transcription Factor-Related Henes
Non-obstructive azoospermia (NOA) is one of the most severe forms of male infertility, but its diagnosis biomarkers with high sensitivity and...
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Feasibility of high-frequency ultrasound for seminiferous tubule assessment and correlation of B-mode imaging with pathological findings in the testis in azoospermia
PurposeTo determine the feasibility of high-frequency ultrasound (HFUS) for assessing seminiferous tubules and to understand high-resolution B-mode...
