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Tidal volume measurement in patients with obesity hypoventilation syndrome and opium dependence
BackgroundBoth obesity hypoventilation syndrome (OHS) and opium dependence can negatively affect nocturnal respiratory functionality. However, the...
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Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD): a collaborative review of the current understanding
PurposeTo provide an overview of the discovery, presentation, and management of Rapid-onset Obesity with Hypothalamic dysfunction, Hypoventilation,...
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Obesity Hypoventilation Syndrome and Postsurgical Outcomes in a Bariatric Surgery Cohort
PurposePatients with obesity and elevated serum bicarbonate suggesting obesity hypoventilation syndrome (OHS) undergoing bariatric surgery may...
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Using intra-breath oscillometry in obesity hypoventilation syndrome to detect tidal expiratory flow limitation: a potential marker to optimize CPAP therapy
BackgroundContinuous positive airway pressure (CPAP) therapy has profound effects in obesity hypoventilation syndrome (OHS). Current therapy...
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A Novel Nomogram and Online Calculator for Predicting the Risk of Obesity Hypoventilation Syndrome in Bariatric Surgery Candidates
BackgroundObesity hypoventilation syndrome (OHS) is frequently misdiagnosed and undertreated, increasing the risk of perioperative complications. We...
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Case report: fast reversal of malignant obesity hypoventilation syndrome after noninvasive ventilation and pulmonary rehabilitation
BackgroundMalignant obesity hypoventilation syndrome (MOHS) is described as a subtype condition of OHS, characterized by extreme obesity,...
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Advances in non-coding RNA as a biomarker for obstructive sleep apnoea hypoventilation syndrome
PurposeObstructive sleep apnoea hypoventilation syndrome (OSAHS) is a common sleep disorder that affects multiple body systems, which in turn is...
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Haematocrit level in obesity hypoventilation syndrome: a predictor of mortality?
BackgroundThe connection between obstructive sleep apnea and secondary erythrocytosis is controversial. We hypothesised that there may be a higher...
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Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of severely obese patients with obesity hypoventilation syndrome but not in the moderately obese
It has been suggested that metabolic dysfunction in obesity is at least in part driven by adipose tissue (AT) hypoxia. However, studies on AT hypoxia...
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Transitional care and clinical management of adolescents, young adults, and suspected new adult patients with congenital central hypoventilation syndrome
PurposeWith contemporaneous advances in congenital central hypoventilation syndrome (CCHS), recognition, confirmatory diagnostics with PHOX2B ...
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A comprehensive review of genetic causes of obesity
BackgroundObesity is a multifactorial chronic disease with a high, increasing worldwide prevalence. Genetic causes account for 7% of the cases in...
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Long-term effectiveness of CPAP in patients with severe obesity-hypoventilation syndrome
PurposeThe optimal mode of long-term positive airway pressure (PAP) treatment for obesity-hypoventilation syndrome (OHS) is not clear. The objectives...
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Obesity at term: What to consider? How to deliver?
Obesity presents significant challenges during pregnancy, increasing the risk of complications and adverse outcomes for both mother and baby. With...
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Genetics and epigenetics in the obesity phenotyping scenario
Obesity is a common complex trait that elevates the risk for various diseases, including type 2 diabetes and cardiovascular disease. A combination of...
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The impact of obesity on ventilator-associated pneumonia, a US nationwide study
BackgroundVentilator-associated pneumonia (VAP) is one of the leading causes of mortality in patients with critical care illness. Since obesity is...
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Exploring the Mechanistic Link Between Obesity and Heart Failure
Abstract Purpose of ReviewAmong subtypes of cardiovascular disease, obesity has a potent and unique association with heart failure (HF) that is...
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Association between obesity and new-onset heart failure among patients with hypertension in Thailand
BackgroundIn Thailand, the epidemiological data on the relationship between obesity and heart failure (HF) among high-risk populations was limited....
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Clinical evaluation of patients living with obesity
Obesity is a significant public health concern which is implicated in cardiometabolic disease, mechanical complications and psychiatric sequelae. BMI...
