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Adjuvant Chemotherapy With or Without Radiotherapy for Resected Pancreatic Cancer After Multiagent Neoadjuvant Chemotherapy
BackgroundAdjuvant therapy is associated with improved pancreatic cancer survival after neoadjuvant chemotherapy and surgery. However, whether...
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Neoadjuvant Chemotherapy or Adjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma
BackgroundChemotherapy and chemoradiation have become essential adjuncts to improve the survival of patients with resectable esophageal squamous cell...
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Evaluation of Histomorphological Changes in Breast Cancer Post-Neoadjuvant Chemotherapy
Breast cancer, a leading cause of global female mortality, demands comprehensive diagnostic and therapeutic strategies. This study delves into the...
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Predictive analysis of breast cancer response to neoadjuvant chemotherapy through plasma metabolomics
PurposePreoperative chemotherapy is a critical component of breast cancer management, yet its effectiveness is not uniform. Moreover, the adverse...
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Pediatric adrenocortical carcinoma: clinical features and application of neoadjuvant chemotherapy
ObjectiveTo summarize the clinical characteristics of children with adrenocortical carcinoma (ACC) and preliminarily explore the indications for and...
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The Role of Neoadjuvant and Adjuvant Chemotherapy in Pancreatic Cancer
Pancreatic cancer is an aggressive malignancy. Recurrences are very high despite high-quality surgery necessitating adjuvant therapy. The evolution...
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Neoadjuvant Gastric Score: How Response to Neoadjuvant Chemotherapy Affects Overall Survival and Adjuvant Benefit
IntroductionThe Neoadjuvant Rectal score (NAR) was developed as a short-term surrogate for 5-year overall survival (OS) prediction in locally...
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Influence of Neoadjuvant Immunotherapy–Chemotherapy on Perioperative Outcomes in Locally Advanced Esophageal Adenocarcinoma
BackgroundThis study evaluated the perioperative outcomes for patients who had locally advanced esophageal adenocarcinoma (EAC) treated with...
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Neoadjuvant PD-1 blockade combined with chemotherapy is not superior to neoadjuvant chemotherapy alone in resectable locally advanced esophageal carcinoma
BackgroundNeoadjuvant chemotherapy (nCT) or neoadjuvant chemoradiotherapy followed by surgery has been recommended as standard treatment in patients...
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A Comparison of Clinicopathologic Outcomes and Patterns of Lymphatic Spread Across Neoadjuvant Chemotherapy, Neoadjuvant Chemoradiotherapy, and Neoadjuvant Immunochemotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma
BackgroundNeoadjuvant chemoradiotherapy (NCRT) is recommended as the treatment standard for locally advanced esophageal squamous cell carcinoma...
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GSDME-mediated pyroptosis promotes anti-tumor immunity of neoadjuvant chemotherapy in breast cancer
Paclitaxel and anthracycline-based chemotherapy is one of the standard treatment options for breast cancer. However, only about 6–30% of breast...
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Computed tomography-based radiomics nomogram for predicting therapeutic response to neoadjuvant chemotherapy in locally advanced gastric cancer
Background and ObjectiveNeoadjuvant chemotherapy results in various responses when used to treat locally advanced gastric cancer, we aimed to develop...
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Preoperative neutrophil-to-lymphocyte ratio predicts recurrence of esophageal squamous cell carcinoma after neoadjuvant triplet chemotherapy
BackgroundNeoadjuvant chemotherapy followed by esophagectomy is the standard treatment for resectable advanced esophageal squamous cell carcinoma...
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When is neoadjuvant chemotherapy indicated in rectal neuroendocrine tumors? An analysis of the National Cancer Database
BackgroundRectal neuroendocrine tumors (rNET) are rare and challenging to manage. While most patients with small rNET can be definitively treated...
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Imaging advances in efficacy assessment of gastric cancer neoadjuvant chemotherapy
Effective neoadjuvant chemotherapy (NAC) can improve the survival of patients with locally progressive gastric cancer, but chemotherapeutics do not...
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In Neoadjuvant FOLFIRINOX Chemotherapy for Pancreatic Ductal Adenocarcinoma, Which Response is the More Reliable Indicator for Prognosis, Radiologic or Biochemical?
BackgroundIn this era of increasing neoadjuvant chemotherapy, methods for evaluating responses to neoadjuvant chemotherapy are still diverse among...
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Neoadjuvant chemotherapy in older patients with gastric cancer undergoing surgery: a population-based cohort study
BackgroundIn trials evaluating perioperative chemotherapy for gastric cancer, which serve as the basis for treatment guidelines, patients are...
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Survival outcomes of neoadjuvant immunochemotherapy versus chemotherapy for locally advanced esophageal squamous cell carcinoma
PurposeNeoadjuvant chemotherapy (NCT) is the standard preoperative treatment for resectable locally advanced esophageal squamous cell carcinoma...
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Predicting response of hepatoblastoma primary lesions to neoadjuvant chemotherapy through contrast-enhanced computed tomography radiomics
ObjectiveTo investigate the clinical value of contrast-enhanced computed tomography (CECT) radiomics for predicting the response of primary lesions...
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Complete reduction surgery of a huge recurrent adult granulosa cell tumor after neoadjuvant chemotherapy
Adult granulosa cell tumors are rare, accounting for only 3–5% of all ovarian tumors. Adult granulosa cell tumors have late recurrences, for which...