Search
Search Results
-
The role of interventional radiology and molecular imaging for near infrared photoimmunotherapy
Near infrared photoimmunotherapy (NIR-PIT) is a recently approved cancer therapy for recurrent head and neck cancer. It involves the intravenous...
-
Multimodality PET and Near-Infrared Fluorescence Intraoperative Imaging of CEA-Positive Colorectal Cancer
PurposeMolecular imaging is a major diagnostic component for cancer management, enabling detection, staging of disease, targeting therapy, and...
-
Application of near-infrared fluorescence imaging in the accurate assessment of surgical margins during breast-conserving surgery
ObjectiveTo evaluate the feasibility and accuracy of near-infrared fluorescence imaging technology for assessing margins during breast-conserving...
-
Molecular fluorophores for in vivo bioimaging in the second near-infrared window
PurposeThis systematic review aims to summarize the current developments of fluorescence and chemi/bioluminescence imaging based on the molecular...
-
Identification of a CEACAM5 targeted nanobody for positron emission tomography imaging and near-infrared fluorescence imaging of colorectal cancer
PurposeHere, we aim to identify a CEACAM5-targeted nanobody and demonstrate its application in positron emission tomography (PET) imaging and...
-
A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer’s Disease Mouse Model
PurposeNoninvasive imaging of protein aggregates in the brain is critical for the early diagnosis, disease monitoring, and evaluation of the...
-
Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer
PurposeFluorescence-guided surgery (FGS) can play a key role in improving radical resection rates by assisting surgeons to gain adequate...
-
The Use of Indocyanine Green and Near-Infrared Fluorescence Imaging Versus Blue Dye in Sentinel Lymph Node Biopsy in Cutaneous Melanoma: A Retrospective, Cohort Study
BackgroundThe use of indocyanine green (ICG) and near-infrared fluorescence imaging is a promising option for sentinel lymph node (SLN) mapping in...
-
Intraoperative near infrared functional imaging of rectal cancer using artificial intelligence methods - now and near future state of the art
Colorectal cancer remains a major cause of cancer death and morbidity worldwide. Surgery is a major treatment modality for primary and, increasingly,...
-
Sentinel Lymph Node Procedure in Pediatric Patients with Melanoma, Squamous Cell Carcinoma, or Sarcoma Using Near-Infrared Fluorescence Imaging with Indocyanine Green: A Feasibility Trial
BackgroundStandard sentinel lymph node procedure (SNP) in pediatric cancer consists of a preoperative injection with 99m technetium nanocolloid in...
-
Comparison of Near-Infrared Imaging Agents Targeting the PTPmu Tumor Biomarker
PurposeMaximal, safe resection of solid tumors is considered a critical first step in successful cancer treatment. The advent of fluorescence...
-
Practical Guidance for Developing Small-Molecule Optical Probes for In Vivo Imaging
The WMIS Education Committee (2019–2022) reached a consensus that white papers on molecular imaging could be beneficial for practitioners of...
-
A novel PSMA targeted dual-function near-infrared fluorescence and PET probe for the image-guided surgery and detection of prostate cancer
PurposeProstate-specific membrane antigen (PSMA) is a promising diagnostic biomarker for prostate cancer (PCa). NYM016, a novel small-molecule...
-
Efficacy of Near-Infrared Fluorescence Video-Assisted Thoracoscopic Surgery for Small Pulmonary Nodule Resection with Indocyanine Green Inhalation: A Randomized Clinical Trial
BackgroundSmall pulmonary nodules (<3 cm) can sometimes be unrecognizable and nonpalpable in video-assisted thoracoscopic surgery (VATS)....
-
Highlighting the Undetectable — Fluorescence Molecular Imaging in Gastrointestinal Endoscopy
AbstractFlexible high-definition white-light endoscopy is the current gold standard in screening for cancer and its precursor lesions in the...
-
Near-infrared II theranostic agents for the diagnosis and treatment of Alzheimer’s disease
BackgroundNear-infrared II theranostic agents have gained great momentum in the research field of AD owing to the appealing advantages. Recently, an...
-
Enhancing surgical outcomes: accurate identification and removal of prostate cancer with B7-H3-targeted NIR-II molecular imaging
PurposeOne of the main reasons for prostate cancer (PCa) recurrence is the difficulty in identifying and removing cancerous lesions during surgery....
-
In Vivo Evaluation of Near-Infrared Fluorescent Probe for TIM3 Targeting in Mouse Glioma
PurposeCurrent checkpoint inhibitor immunotherapy strategies in glioblastoma are challenged by mechanisms of resistance including an...
-
3D-Printed Tumor Phantoms for Assessment of In Vivo Fluorescence Imaging Analysis Methods
PurposeInterventional fluorescence imaging is increasingly being utilized to quantify cancer biomarkers in both clinical and preclinical models, yet...
-
Sensitive and specific detection of breast cancer lymph node metastasis through dual-modality magnetic particle imaging and fluorescence molecular imaging: a preclinical evaluation
PurposeA sensitive and specific imaging method to detect metastatic cancer cells in lymph nodes to detect the early-stage breast cancer is still a...
