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NETosis and kidney disease: what do we know?
Neutrophils are the most abundant leukocytes in the blood. They are rapidly mobilized from the circulation to sites of inflammation and/or infection....
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Perioperative NETosis and Cancer Progression: Current Evidence and Future Perspectives
Purpose of reviewThe process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar death modality of neutrophils, which...
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A2AR-mediated CXCL5 upregulation on macrophages promotes NSCLC progression via NETosis
Tumor-associated macrophages (TAMs) are abundant in tumors and interact with tumor cells, leading to the formation of an immunosuppressive...
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NETosis and SARS-COV-2 infection related thrombosis: a narrative review
BackgroundCoronavirus disease 2019 (COVID-19) infection is related to immune hyperactivity, the release of inflammatory cytokines, and...
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Multiomics integration reveals NETosis heterogeneity and TLR2 as a prognostic biomarker in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant neoplasm characterized by a poor prognosis and limited therapeutic strategy. The PDAC...
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Prognostic impact and immunotherapeutic implications of NETosis-related prognostic model in clear cell renal cell carcinoma
BackgroundThe ramifications of necroptosis on the prognostication of clear cell renal cell carcinoma (ccRCC) remain inadequately expounded.
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NEUT-RI, a surrogate marker of NETosis is lower in patients with strong IgM antiphospholipid antibodies
BackgroundAntiphospholipid antibody syndrome (APS) is an acquired autoimmune disorder characterized by recurrent venous or arterial thrombosis and/or...
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Neutrophil activation and NETosis are the predominant drivers of airway inflammation in an OVA/CFA/LPS induced murine model
BackgroundAsthma is one of the most common chronic diseases that affects more than 300 million people worldwide. Though most asthma can be well...
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NETosis in Rheumatic Diseases
Purpose of ReviewNeutrophils are the most numerous and the first responder cells of the innate immune system. Evidence suggests that neutrophils may...
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Insight into antiphospholipid syndrome: the role and clinical utility of neutrophils extracellular traps formation
Antiphospholipid syndrome (APLS) is a systemic immune dysregulation distinguished by repetitive complications and pregnancy loss in the absence of...
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Neutrophil extracellular traps (NETs), transfusion requirements and clinical outcomes in orthotopic liver transplantation
Inflammatory phenomena have a direct impact on the prognosis of orthotopic liver transplantation (OLT). Neutrophil extracellular traps (NETs)...
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Role and intervention of PAD4 in NETs in acute respiratory distress syndrome
BackgroundSepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Acute respiratory distress syndrome...
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Effect of Thoracic Epidural Anesthesia on Perioperative Neutrophil Extracellular Trapping Markers in Patients Undergoing Anesthesia and Surgery for Colorectal Cancer: A Randomized, Controlled Trial
BackgroundNeutrophil extracellular trapping (NETosis) is an immunologic mechanism strongly linked with increased metastatic risk in colorectal...
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Neutrophil degranulation and severely impaired extracellular trap formation at the basis of susceptibility to infections of hemodialysis patients
BackgroundChronic kidney disease patients are at increased risk of mortality with cardiovascular diseases and infections as the two leading causes of...
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The potential roles of type I interferon activated neutrophils and neutrophil extracellular traps (NETs) in the pathogenesis of primary Sjögren’s syndrome
ObjectiveNeutrophils and aberrant NETosis have been implicated in the pathogenesis of diverse autoimmune diseases; however, their roles in primary...
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Lidocaine effects on neutrophil extracellular trapping and angiogenesis biomarkers in postoperative breast cancer patients with different anesthesia methods: a prospective, randomized trial
BackgroundAnesthesia techniques and drug selection may influence tumor recurrence and metastasis. Neutrophil extracellular trapping (NETosis), an...
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Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs)
BackgroundCayratia albifolia C.L.Li (CAC), commonly known as “Jiao-Mei-Gu” in China, has been extensively utilized by the Dong minority for several...
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NETosis in cancer: a critical analysis of the impact of cancer on neutrophil extracellular trap (NET) release in lung cancer patients vs. mice
Neutrophils play a major role in tumor biology. Among other functions, neutrophils can release extracellular traps (NETs), mesh-like structures of...
