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Sampling weighting strategies in causal mediation analysis
BackgroundCausal mediation analysis plays a crucial role in examining causal effects and causal mechanisms. Yet, limited work has taken into...
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Practical challenges in mediation analysis: a guide for applied researchers
Mediation analysis is a statistical approach that can provide insights regarding the intermediary processes by which an intervention or exposure...
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Estimation and inference for the mediation effect in a time-varying mediation model
BackgroundTraditional mediation analysis typically examines the relations among an intervention, a time-invariant mediator, and a time-invariant...
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Intimate Partner Violence Predicting Outcomes in Specialized Mediation and Traditional Litigation
PurposeWe investigated intimate partner violence (IPV) victimization level ever in the relationship, as reported by parents at baseline, as a...
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High-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study
BackgroundMediation analysis is a powerful tool to identify factors mediating the causal pathway of exposure to health outcomes. Mediation analysis...
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Effects of perceived stress on turnover intention of female healthcare staff: a serial multiple mediation model
BackgroundHealthcare staff in China, especially females, work in a high-pressure, high-load, and high-risk environment, which affects the physical...
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The explanation of educational disparities in adiposity by lifestyle, socioeconomic and mental health mediators: a multiple mediation model
BackgroundThe inverse association between education and obesity was previously found in numerous studies. This study aims to assess several possible...
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Longitudinal relationship between social participation, depressive symptoms, and activity impairment among older patients with arthritis: a moderated mediation analysis
BackgroundArthritis primarily affects older people and is a prominent cause of their activity impairment. This study aimed to examine the mediating...
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Character Strengths, Coping, and Addiction Recovery: a Mediation Analysis
The present cross-sectional online survey study explored the relationship between character strengths, coping, and addiction recovery in a sample of...
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Neighborhood safety perception and depressive symptoms in China: a moderated mediation relationship
PurposeDespite rich data on neighborhood safety perception’s role in shaping depressive symptoms, a comprehensive view of this dynamic interplay...
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Required sample size to detect mediation in 3-level implementation studies
BackgroundStatistical tests of mediation are important for advancing implementation science; however, little research has examined the sample sizes...
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Association Between E-cigarette Exposure and Susceptibility: the Mediation Effect of Perception
This study aims to explore the relationship between e-cigarette social environment exposure, perceptions, and susceptibility. We surveyed 4290 middle...
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The relationship between childhood psychological abuse and depression in college students: a moderated mediation model
BackgroundChildhood psychological abuse (CPA) are highly correlated with depression among college students, but the underlying mechanisms between...
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Analysis of the chain mediation effect between intergenerational support and mental health of older adults in urban China: a structural equation model
BackgroundThis study aimed investigate the impact of intergenerational support on the mental health of older adults in urban China. It also sought to...
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Temporal relationship between hepatic steatosis and blood pressure elevation and the mediation effect in the development of cardiovascular disease
The temporal relationship between non-alcoholic fatty liver disease (NAFLD) and hypertension remains highly controversial, with ongoing debates on...
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Liver indicators affecting the relationship between BMI and hypertension in type 2 diabetes: a mediation analysis
BackgroundBody mass index (BMI) is an important risk factor for hypertension in diabetic patients. However, the underlying mechanisms remain poorly...
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The effect of metabolic factors on the association between hyperuricemia and chronic kidney disease: a retrospective cohort mediation analysis
BackgroundHyperuricemia, hyperglycemia, hypertension, hyperlipidemia, and hyperhomocysteinemia are all established risk factors for chronic kidney...
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Mediation effect of antithrombin III between chronic renal insufficiency and chronic coronary artery disease in T2DM patients
PurposeThe study aimed to investigate the potential effect of Antithrombin III (ATIII) between chronic renal insufficiency and chronic coronary...
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Lipids as potential mediators linking body mass index to diabetes: evidence from a mediation analysis based on the NAGALA cohort
BackgroundBody mass index (BMI) and lipid disorders are both known to be strongly associated with the development of diabetes, however, the indirect...
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What are the pathways between poverty and malaria in sub-Saharan Africa? A systematic review of mediation studies
BackgroundMalaria remains a major burden in sub-Saharan Africa (SSA). While an association between poverty and malaria has been demonstrated, a...
