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Expression of Interleukin-8, Interleukin-12 and Interleukin-13 in Esophageal Squamous Cell Carcinoma: Biomarker Potentiality and Prognostic Significance
PurposeInterleukin-8 (IL8), Interleukin-12 (IL12) and Interleukin-13 (IL13) are cytokines that play regulatory role in cancer pathogenesis. We...
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Evaluation of serum interleukin-17 A and interleukin-22 levels in pediatric patients with autism spectrum disorder: a pilot study
BackgroundMany neurodevelopmental abnormalities are connected to autism spectrum disorder (ASD), which can result in inflammation and elevated...
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Association of interleukin-2 and interleukin-10 with the pathophysiology and development of generalized anxiety disorder: a case-control study
BackgroundGeneralized anxiety disorder (GAD) is a devastating mental health condition characterized by constant, uncontrolled worrying. Recent...
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Profiles of plasma interleukin-6 and interleukin-10 in relation to some haematologic alterations following colo-peritoneo-cystoplasty in dogs
Systemic inflammatory response to surgical interventions has been characterized by an orchestrated interplay of endogenous mediatory cytokines and...
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Role of nuclear factor kappa B, interleukin-19, interleukin-34, and interleukin-37 expression in diabetic nephropathy
BackgroundThe long-term effects of diabetes mellitus (DM) can impair several organs, including the kidney, resulting in serious health problems....
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Interleukin-22 Alleviates Caerulein-Induced Acute Pancreatitis by Activating AKT/mTOR Pathway
BackgroundAcute pancreatitis (AP) is one of the most common acute abdominal disorders; due to the lack of specific treatment, the treatment of acute...
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Assessment of serum interleukin 6 in a sample of Egyptian patients with schizophrenia
BackgroundInflammation has been demonstrated to play a pathophysiological function in schizophrenia. Raised interleukin-6 (IL-6) levels have been the...
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Speed and Cumulative Responses According to Body Regions in Patients with Moderate-to-Severe Plaque Psoriasis Treated with Ixekizumab (Interleukin-17A Antagonist) versus Guselkumab (Interleukin-23p19 Inhibitor)
IntroductionWhen assessing the effect of a therapy for psoriasis (PsO), it is important to consider speed of response and cumulative response....
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Interleukin-22/Interleukin-22 binding protein axis and oral contraceptive use in polycystic ovary syndrome
PurposePolycystic ovary syndrome (PCOS) is associated with alterations in gut microbiota. The cytokine interleukin-22 (IL-22) is produced by immune...
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Remission einer therapierefraktären generalisierten pustulösen Psoriasis unter dem Interleukin-36-Rezeptor-Inhibitor Spesolimab
Generalized pustular psoriasis (GPP) is often a life-threatening disease which, in contrast to psoriasis vulgaris, is associated with the formation...
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Muscle-to-organ cross-talk mediated by interleukin 6 during exercise: a review
Physical activity is increasingly recommended as a therapeutic approach for various lifestyle-related conditions, including type 2 diabetes,...
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Assessment of interleukin 6 (IL-6) as a marker of inflammation among adult patients with pulmonary tuberculosis in Zaria, Nigeria
Tuberculosis (TB) remains a significant cause of morbidity and mortality worldwide. Complications of the disease are associated with the host’s...
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Association of interleukin-36α and interleukin-38 with type 2 diabetes mellitus and diabetic neuropathy
BackgroundInterleukin (IL)-36α and IL-38, two novel cytokines of the IL-1 family, have recently been proposed to have a pathophysiological...
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Cut-off values of serum interleukin-6 for culture-confirmed sepsis in neonates
IntroductionNeonatal sepsis accounts for 0.97% of all disability-adjusted life years worldwide. Interleukin-6 has been used in sepsis diagnosis, but...
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Interleukin-22 and interleukin-33 show up-regulated levels in the serum of patients with mild/moderate Coronavirus disease 2019
BackgroundThis study analyzed serum concentrations of interleukin (IL)-22 and IL-33 (pro-inflammatory and anti-inflammatory cytokines) in 90 patients...
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Highlighting allelic variations at the interleukin-19 locus in term of preeclampsia predisposing factors and access to an accurate diagnostic/screening option
BackgroundPreeclampsia is the main cause of preterm parturition and maternal–fetal complications. T helper 1 and T helper 2 cytokines balance is a...
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Interleukin-12 in multimodal tumor therapies for induction of anti-tumor immunity
Interleukin-12 (IL-12) can be used as an immunomodulator in cancer immunotherapy. And it has demonstrated enormous potential in inhibiting tumor...
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Activation of the interleukin-23/Th17 axis in major depression: a systematic review and meta-analysis
The interleukin-23/Th17 axis is a promising modifiable target for depression. However, its association with depression has not been systematically...
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The pertinence of gastric cancer and interleukin 10–819 single nucleotide polymorphisms: a meta-analysis and systematic review
PurposeCytokines regulate the interaction between the immune system and malignant tumors. Among them, interleukin-10 (IL-10) is a multifunctional...
