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Deep learning generates synthetic cancer histology for explainability and education
Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with...
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Uncommon Histology of Adnexal Masses: a Case Series
Adnexal masses can arise from the uterus, ovary, fallopian tubes, or surrounding tissues. They often pose diagnostic and management dilemmas. This...
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In vivo organoid growth monitoring by stimulated Raman histology
Patient-derived tumor organoids have emerged as a crucial tool for assessing the efficacy of chemotherapy and conducting preclinical drug screenings....
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Histology-specific standardized incidence ratio improves the estimation of second primary lung cancer risk
BackgroundLung cancer (LC) survivors are at increased risk for developing a second primary cancer (SPC) compared to the general population. While...
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Opportunities and Challenges for a Histology-Agnostic Utilization of Trastuzumab Deruxtecan
Purpose of ReviewThis review delves into the prospects and challenges offered by a potential pan-histological utilization of trastuzumab deruxtecan...
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Concordance between renal tumour biopsy and robotic-assisted partial and radical nephrectomy histology: a 10-year experience
We aimed to assess concordance between renal tumour biopsy (RTB) and surgical pathology from robotic-assisted partial nephrectomy (RAPN) or...
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Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular–mucocellular histology
IntroductionGastric cancer with fusion genes involving the Rho GTPase-activating protein domain (RhoGAP-GC) is mainly included in the genomically...
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The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis
BackgroundMASLD can manifest as hepatocellular damage, which can result in mild elevation of aminotransferases. However, in some patients, MASLD...
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Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI)
BackgroundTo confirm the diagnosis of periprosthetic joint infection (PJI), the Infectious Diseases Society of America (IDSA) and the International...
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Neoadjuvant chemotherapy for muscle-invasive bladder cancer: does variant histology matter?
PurposeThe most frequent histology of bladder tumors is urothelial carcinoma. Most are pure urothelial carcinomas (PUC) but up to one-third of the...
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Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study
IntroductionThe Laurén classification is widely used for Gastric Cancer (GC) histology subtyping. However, this classification is prone to...
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Prognosis and histology of sporadic synchronous and metachronous meningiomas and comparative analyses with singular lesions
Synchronous or metachronous growth of multiple tumors (≥ 2) is found in up to 20% of meningioma patients. However, biological as well as histological...
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A deep-learning-based model for assessment of autoimmune hepatitis from histology: AI(H)
Histological assessment of autoimmune hepatitis (AIH) is challenging. As one of the possible results of these challenges, nonclassical features such...
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Mapping high-grade glioma immune infiltration to 5-ALA fluorescence levels: TCGA data computation, classical histology, and digital image analysis
PurposeResection of high-grade gliomas has been considerably improved by 5-aminolevulinic acid (5-ALA). However, not all neurobiological properties...
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Melanin-dependent tissue interactions induced by a 755-nm picosecond-domain laser: complementary visualization by optical imaging and histology
Fractional picosecond-domain lasers (PSL) induce optical breakdown, which correlates histologically to vacuolization in the epidermis and dermis. In...
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MRI-based automated machine learning model for preoperative identification of variant histology in muscle-invasive bladder carcinoma
ObjectivesIt is essential yet highly challenging to preoperatively diagnose variant histologies such as urothelial carcinoma with squamous...
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Sonic hedgehog hepatocellular adenoma: magnetic resonance imaging features and correlation with histology
ObjectivesSonic hedgehog hepatocellular adenoma (shHCA) is a new hepatocellular adenoma (HCA) subgroup characterized by high risk of hemorrhage....
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Cancer drug sensitivity prediction from routine histology images
Drug sensitivity prediction models can aid in personalising cancer therapy, biomarker discovery, and drug design. Such models require survival data...
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Complete investigations (autopsy, toxicology, and histology) in a death due to apixaban overdose
The dead body of a 54-year-old man was found at home by his partner. He was off work due to depression. A letter with suicidal intention was present...
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Histology-Agnostic Drugs: A Paradigm Shift—A Narrative Review
Cancer diagnosis and therapeutics have been traditionally based on pathologic classification at the organ of origin. The availability of an...
