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Prognostic associations of cortical gyrification in minimally medicated schizophrenia in an early intervention setting
The aberration in cortical gyrification seen in schizophrenia likely originates in the earliest phase of life, as gyrification begins in utero and...
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Associations of gestational age with gyrification and neurocognition in healthy adults
Epidemiological studies have shown that gestational age and birth weight are linked to cognitive performance in adults. On a neurobiological level,...
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Cortical morphological changes in multiple sclerosis patients: a study of cortical thickness, sulcal depth, and local gyrification index
PurposeMultiple sclerosis (MS) is a disease that progresses not only with demyelination but also with neurodegeneration. One of the goals of drug...
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Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration
Anomalous patterns of brain gyrification have been reported in major psychiatric disorders, presumably reflecting their neurodevelopmental pathology....
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Reduced cortical gyrification in the posteromedial cortex in unaffected relatives of schizophrenia patients with high genetic loading
Although abnormal cortical gyrification has been consistently reported in patients with schizophrenia, whether gyrification abnormalities reflect a...
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Early alterations of cortical thickness and gyrification in migraine without aura: a retrospective MRI study in pediatric patients
BackgroundMigraine is the most common neurological disease, with high social-economical burden. Although there is growing evidence of brain...
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Brain structure underlying the empathizing–systemizing difference in children with autism spectrum disorder
BackgroundBehavioral research has shown that children with autism spectrum disorder (ASD) have a higher empathizing–systemizing difference (D score)...
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Daily-Life Negative Affect in Emotional Distress Disorders Associated with Altered Frontoinsular Emotion Regulation Activation and Cortical Gyrification
BackgroundEmotional distress disorders are characterized by high daily-life negative affect and impaired positive reappraisal emotion regulation...
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Maternal psychological distress during the COVID-19 pandemic and structural changes of the human fetal brain
BackgroundElevated maternal psychological distress during pregnancy is linked to adverse outcomes in offspring. The potential effects of intensified...
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Brain structural and functional outcomes in the offspring of women experiencing psychological distress during pregnancy
In-utero exposure to maternal psychological distress is increasingly linked with disrupted fetal and neonatal brain development and long‐term...
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Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes
Over the last five decades, a large body of evidence has accrued for structural and metabolic brain alterations in schizophrenia. Here we provide an...
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Cortical changes in the brain of patients with hemifacial spasm
ObjectiveHemifacial spasm (HFS) is a movement disorder characterized by involuntary muscle contractions on one side of the face. It is associated...
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The longitudinal bidirectional relationship between autistic traits and brain morphology from childhood to adolescence: a population-based cohort study
ObjectiveAutistic traits are associated with alterations in brain morphology. However, the anatomic location of these differences and their...
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Identifying Leukoaraiosis with Mild Cognitive Impairment by Fusing Multiple MRI Morphological Metrics and Ensemble Machine Learning
Leukoaraiosis (LA) is strongly associated with impaired cognition and increased dementia risk. Determining effective and robust methods of...
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Alteration of the cortical morphology in classical trigeminal neuralgia: voxel-, deformation-, and surface-based analysis
ObjectiveThis study aimed to combine voxel-based morphometry, deformation-based morphometry, and surface-based morphometry to analyze gray matter...
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Dietary patterns, brain morphology and cognitive performance in children: Results from a prospective population-based study
Dietary patterns in childhood have been associated with child neurodevelopment and cognitive performance, while the underlying neurobiological...
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Preoperative serum cortisone levels are associated with cognition in preschool-aged children with tetralogy of Fallot after corrective surgery: new evidence from human populations and mice
BackgroundTetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Children with TOF would be confronted with neurological...
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Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk
Studies in post-mortem human brain tissue have associated major depressive disorder (MDD) with cortical transcriptomic changes, whose potential in...
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Multimodal prognosis of negative symptom severity in individuals at increased risk of developing psychosis
Negative symptoms occur frequently in individuals at clinical high risk (CHR) for psychosis and contribute to functional impairments. The aim of this...
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Insula sub-regions across the psychosis spectrum: morphology and clinical correlates
The insula is a heterogeneous cortical region, comprised of three cytoarchitecturally distinct sub-regions (agranular, dysgranular, and granular),...
