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  1. Glioma

    Gliomas are primary brain tumours that are thought to develop from neural stem or progenitor cells that carry tumour-initiating genetic alterations....

    Michael Weller, Patrick Y. Wen, ... Guido Reifenberger in Nature Reviews Disease Primers
    Article 09 May 2024
  2. Glioma grade and post-neurosurgical meningitis risk

    Background

    Post-neurosurgical meningitis (PNM) constitutes a grave complication associated with substantial morbidity and mortality. This study aimed...

    Sakke Niemelä, Jarmo Oksi, ... Dan Laukka in Acta Neurochirurgica
    Article Open access 18 July 2024
  3. Thrombospondin-2 promotes the proliferation and migration of glioma cells and contributes to the progression of glioma

    Background

    Gliomas, especially high-grade gliomas, are highly malignant with a poor prognosis. Although existing treatments have improved the survival...

    Tian-Lan Huang, Yi-Wen Mei, ... Hai-Feng Shu in Chinese Neurosurgical Journal
    Article Open access 07 December 2022
  4. Cellular senescence in glioma

    Introduction

    Glioma is the most common primary brain tumor and is often associated with treatment resistance and poor prognosis. Standard treatment...

    Rafał Chojak, Jawad Fares, ... Maciej S. Lesniak in Journal of Neuro-Oncology
    Article 17 July 2023
  5. Deciphering glioma epitranscriptome: focus on RNA modifications

    Gliomas are highly malignant tumors accounting for the majority of brain neoplasms. They are characterized by nuclear atypia, high mitotic rate and...

    Christina Piperi, Mariam Markouli, ... Athanasios G. Papavassiliou in Oncogene
    Article 15 June 2023
  6. Perioperative Neurocognitive Function in Glioma Surgery

    Purpose of Review

    This review provides a concise overview of the recent literature regarding preoperative and postoperative neurocognitive functioning...

    Kyle R. Noll, Mariana Bradshaw, ... Jeffrey S. Wefel in Current Oncology Reports
    Article 04 April 2024
  7. CPLX2 is a novel tumor suppressor and improves the prognosis in glioma

    Background

    Glioma is a type of malignant cancer that affect the central nervous system. New predictive biomarkers have been investigated in recent...

    Yuanbing Chen, Jieling Ning, ... Jun Huang in Journal of Neuro-Oncology
    Article 01 March 2024
  8. Radiotherapy for pediatric low-grade glioma

    Introduction

    Radiotherapy is a highly effective treatment for pediatric low-grade glioma, serving as the standard for evaluating progression-free and...

    Indu Bansal, Thomas E. Merchant in Child's Nervous System
    Article 22 May 2024
  9. Plasma alpha B crystallin as potential biomarker for predicting pre-operative seizures in glioma

    Purpose

    Glioma-associated epilepsy affects a significant proportion of glioma patients, contributing to disease progression and diminished survival...

    Yongsheng Xie, Zengxin Qi, ... Nan Zhou in BMC Neurology
    Article Open access 06 July 2024
  10. Unveiling the therapeutic prospects of IFNW1 and IFNA21: insights into glioma pathogenesis and clinical significance

    Glioma, a type of brain tumor, poses significant challenges due to its heterogeneous nature and limited treatment options. Interferon-related genes...

    Hong Cheng, Yingjie Zhao, ... Yasen Cao in Neurogenetics
    Article 03 July 2024
  11. Prognostic factors analysis of diffuse midline glioma

    Purpose

    This study retrospectively analyzes cases of diffuse midline glioma treated with radiotherapy, with the aim of investigating the prognosis of...

    Jing Jiang, Wen-bin Li, Shao-wen Xiao in Journal of Neuro-Oncology
    Article Open access 21 February 2024
  12. Liquid biomarkers in glioma

    An ideal biomarker must meet several parameters to enable its successful adoption; however, the nature of glioma makes it challenging to discover...

    Sho Tamai, Toshiya Ichinose, Mitsutoshi Nakada in Brain Tumor Pathology
    Article 17 February 2023
  13. HOXD9 is a potential prognostic biomarker involved in immune microenvironment of glioma

    Background

    Glioma is the prevailing malignant tumor affecting the brain and central nervous system, constituting over 80% of all malignant brain...

    Sumei Xu, Haiyan Xiao, ... Minghao Jiang in Journal of Cancer Research and Clinical Oncology
    Article 21 August 2023
  14. Glioma-associated macrophages: unraveling their dual role in the microenvironment and therapeutic implications

    Glioblastoma (GBM) is a malignant brain glioma characterized by a high number of tumor-associated macrophages (TAMs) within its tissues. These TAMs...

    Jiachen Wang, Shenglan Li, ... Wenbin Li in Current Medicine
    Article Open access 07 April 2024
  15. Hypoxic microenvironment-induced exosomes confer temozolomide resistance in glioma through transfer of pyruvate kinase M2

    Objective

    Glioma, a malignant primary brain tumor, is notorious for its high incidence rate. However, the clinical application of temozolomide (TMZ)...

    Guofu Li, Ziyu Xiong, ... Changbin Shi in Discover Oncology
    Article Open access 10 April 2024
  16. Prognostic values and immune infiltration of KLF15, AQP7, AGPAT9 in glioma and glioblastoma

    Backgrounds

    The overall survival of patients with lower-grade gliomas and glioblastoma varies greatly. No reliable or existing procedures can...

    Ayobami Matthew Olajuyin, Onyinyechi Sharon Nwachukwu, ... Adebola Idowu Akingbade in Future Journal of Pharmaceutical Sciences
    Article Open access 04 March 2024
  17. Risk Factors and Predictive Nomogram for Survival in Elderly Patients with Brain Glioma

    Objective

    To determine the factors that contribute to the survival of elderly individuals diagnosed with brain glioma and develop a prognostic...

    Zhi-cheng Fan, Wen-jian Zhao, ... Liang Wang in Current Medical Science
    Article 11 July 2024
  18. FERMT1 suppression induces anti-tumor effects and reduces stemness in glioma cancer cells

    Objective

    Glioma is a leading cause of mortality worldwide, its recurrence poses a major challenge in achieving effective treatment outcomes. Cancer...

    Zhigang Pan, Chuhan Ke, ... Weipeng Hu in Journal of Cancer Research and Clinical Oncology
    Article Open access 08 July 2024
  19. Recent Update on PET/CT Radiotracers for Imaging Cerebral Glioma

    Positron emission tomography/computed tomography (PET/CT) has dramatically altered the landscape of noninvasive glioma evaluation, offering...

    Dongwoo Kim, Suk-Hyun Lee, ... Mijin Yun in Nuclear Medicine and Molecular Imaging
    Article 21 February 2024
  20. Association between viral infections and glioma risk: a two-sample bidirectional Mendelian randomization analysis

    Background

    Glioma is one of the leading types of brain tumor, but few etiologic factors of primary glioma have been identified. Previous observational...

    Sheng Zhong, Wenzhuo Yang, ... Yonggao Mou in BMC Medicine
    Article Open access 05 December 2023
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