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Association of autoantibody levels with different stages of age-related macular degeneration (AMD): Results from the population-based Gutenberg Health Study (GHS)
PurposeAnti-retinal autoantibodies are assumed to be associated with age-related macular degeneration (AMD). To our knowledge, this is the first...
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GHS-R suppression in adipose tissues protects against obesity and insulin resistance by regulating adipose angiogenesis and fibrosis
Background/ObjectivesGhrelin is an orexigenic hormone that increases food intake, adiposity, and insulin resistance through its receptor Growth...
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Glans hypermobility scale (GHS): A simple grading scale and description of a modified glanspexy technique
Glans hypermobility (GH) is a well-described clinical entity that can have significant implications for cosmesis and function, resulting in sexual...
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Much higher prevalence of keratoconus than announced results of the Gutenberg Health Study (GHS)
AbstractKeratoconus appears to be a rare corneal disease with a prevalence previously estimated at 1:2000. The aim of our study was to investigate...
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Five-year cumulative incidence and progression of age-related macular degeneration: results from the German population-based Gutenberg Health Study (GHS)
PurposeAge-related macular degeneration (AMD) is a major cause of visual impairment and blindness. This study evaluates the incidence and progression...
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Enhanced systematic delivery of fluconazole-loaded biotin-glutathione functionalized chitosan-g-proline carrier into the infected retinitis treatment
BackgroundThe polymer-based facile and effective drug carrier approach was developed to treat superficial fungal infected retinopathy infections.
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Racial and ethnic disparities in self-reported general and mental health status among colorectal cancer survivors: impact of sociodemographic factors and implications for mortality—a SEER-CAHPS study
PurposePatient-reported outcomes are recognized as strong predictors of cancer prognosis. This study examines racial and ethnic differences in...
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Pandemic preparedness improves national-level SARS-CoV-2 infection and mortality data completeness: a cross-country ecologic analysis
BackgroundHeterogeneity in national SARS-CoV-2 infection surveillance capabilities may compromise global enumeration and tracking of COVID-19 cases...
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Development and validation of parent-reported gastrointestinal health scale in MECP2 duplication syndrome
Background/aimsWe aimed to develop a validated patient-reported Gastrointestinal Health Scale (GHS) specific to MECP2 Duplication Syndrome (MDS) to...
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Health-Related Quality of Life with Pembrolizumab in Patients with Locally Advanced or Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma: KEYNOTE-629
IntroductionAt first interim analysis of KEYNOTE-629, health-related quality of life (HRQoL) with pembrolizumab was stable or improved over 48 weeks...
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Tailored vs. General COVID-19 prevention for adults with mental disabilities residing in group homes: a randomized controlled effectiveness-implementation trial
BackgroundPeople with serious mental illness (SMI) and people with intellectual disabilities/developmental disabilities (ID/DD) are at higher risk...
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The role of universal health coverage and global health security nexus and interplay on SARS-CoV-2 infection and case-fatality rates in Africa : a structural equation modeling approach
BackgroundThe Coronavirus Disease (COVID-19) caused by SARS-CoV-2 infections remains a significant health challenge worldwide. There is paucity of...
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Quality of Life Analysis of Patients Treated with Percutaneous Hepatic Perfusion for Uveal Melanoma Liver Metastases
PurposePercutaneous hepatic perfusion with melphalan (M-PHP) is a minimally invasive therapy with proven efficacy in patients with uveal melanoma...
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Longitudinal changes of health-related quality of life over 10 years in breast cancer patients treated with radiotherapy following breast-conserving surgery
PurposesThe study intended to (1) assess changes of health-related quality of life (HRQoL) between early treatment-related time points and 10 years...
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Bewusstsein für eine Glaukomerkrankung in der Bevölkerung
BackgroundGlaucoma is not a rare entity but because very few symptoms occur and visual field defects are frequently first recognized at a late stage,...
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Gut microbial CAZymes markers for depression
Major depressive disorder (MDD) is a serious mental illness, characterized by disturbances of gut microbiome, it is required to further explore how...
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Safety culture and perception of warning signs of chemical hazards among hospital cleaning workers: a cross-sectional study
BackgroundDue to the type of activities and the long-term exposure to chemicals, hospital cleaning workers require the necessary knowledge about the...
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Improving Communication in a Large Urban Academic Safety Net Hospital System: Implementation of Secure Messaging
Given the complexities of communication within health systems, we investigated how the implementation of secure messaging in addition to traditional...
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Temporal trends in self-reported general and mental health status among colorectal cancer patients: racial/ethnic disparities in a population-based analysis
PurposePatient-reported outcomes are essential to patient-centered cancer care. We sought to determine the relationships between colorectal cancer...
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Public relations strategies employed by the Ghana Health Service to address COVID-19 vaccine hesitancy: a qualitative inquiry
BackgroundStrategies for developing and advancing good public relations can be recognized in nearly all fields of life without making an exception...