Search
Search Results
-
Prognostic value of the liver fibrosis marker fibrosis-5 index in patients with severe isolated tricuspid regurgitation: comparison with fibrosis-4 index
The fibrosis-4 index (FIB4), a liver fibrosis maker, has been shown to be associated with the prognosis in patients with severe isolated tricuspid...
-
Ovarian fibrosis: molecular mechanisms and potential therapeutic targets
Ovarian fibrosis, characterized by the excessive proliferation of ovarian fibroblasts and the accumulation of extracellular matrix (ECM), serves as...
-
Interstitial Lung Abnormalities (ILA) and Pulmonary Fibrosis
Purpose of ReviewThis review identifies the similarities and differences between interstitial lung abnormalities (ILA) and pulmonary fibrosis in...
-
Inflammation accelerating intestinal fibrosis: from mechanism to clinic
Intestinal fibrosis is a prevalent complication of IBD that that can frequently be triggered by prolonged inflammation. Fibrosis in the gut can cause...
-
Liver fibrosis analysis using digital pathology
Digital pathology has enabled the noninvasive quantification of pathological parameters. In addition, the combination of digital pathology and...
-
Regulation of myofibroblast dedifferentiation in pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lethal, progressive, and irreversible condition that has become a significant focus of medical research due to its...
-
Comparative microbiome analysis in cystic fibrosis and non-cystic fibrosis bronchiectasis.
BackgroundBronchiectasis is a condition characterized by abnormal and irreversible bronchial dilation resulting from lung tissue damage and can be...
-
Mitophagy in renal interstitial fibrosis
As a high energy consumption organ, kidney relies on a large number of mitochondria to ensure normal physiological activities. Under specific...
-
Metabolomic insights into pulmonary fibrosis: a mendelian randomization study
BackgroundThis study leverages a two-sample Mendelian Randomization (MR) approach to explore the causal relationships between 1,400 metabolites and...
-
Intravoxel incoherent motion assessment of liver fibrosis staging in MASLD
PurposePartial correlation analysis was performed to account for the interference of steatosis changes and inflammatory factors, to determine the...
-
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway
ObjectiveRenal fibrosis is the ultimate pathway of various forms of acute and chronic kidney damage. Notably, the knockout of transient receptor...
-
Hepatic inflammatory responses in liver fibrosis
Chronic liver diseases such as nonalcoholic fatty liver disease (NAFLD) or viral hepatitis are characterized by persistent inflammation and...
-
Quantitative measurements of M2BPGi depend on liver fibrosis and inflammation
BackgroundThe relationship between liver fibrosis and inflammation and Mac-2-binding protein glycosylation isomer (M2BPGi) in patients with chronic...
-
Comparative Accuracy of Clinical Fibrosis Markers, Hepascore and Fibroscan® to Detect Advanced Fibrosis in Patients with Nonalcoholic Fatty Liver Disease
BackgroundNon-invasive tests are widely used to diagnose fibrosis in patients with non-alcoholic fatty liver disease (NAFLD), however, the optimal...
-
Kidney fibrosis: from mechanisms to therapeutic medicines
Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney fibrosis, characterized by excessive extracellular matrix...
-
Pathophysiology of Radiation Fibrosis Syndrome
Purpose of ReviewThe goal of this article is to provide an overview of radiation therapy followed by a description of the pathophysiology underlying...
-
Single-cell sequencing analysis fibrosis provides insights into the pathobiological cell types and cytokines of radiation-induced pulmonary fibrosis
BackgroundRadiotherapy is an essential treatment for chest cancer. Radiation-induced pulmonary fibrosis (RIPF) is an almost irreversible interstitial...
-
Genetic-driven biomarkers for liver fibrosis through bioinformatic approach
BackgroundLiver fibrosis is a widespread chronic liver ailment linked to substantial mortality and limited therapeutic options. An in-depth...
-
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1
ObjectiveBladder outlet obstruction (BOO) results in significant fibrosis in the chronic stage and elevated bladder pressure. Piezo1 is a type of...
-
MAFLD identifies patients with significant hepatic fibrosis better than MASLD
Background and aimsDiagnostic criteria for metabolic dysfunction-associated steatotic liver disease (MASLD) have been proposed but not yet validated....
