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Treatment of primary epididymal adenocarcinoma: a case report and review of the literature
BackgroundEpididymal tumors, especially malignant tumors, have low incidence and are rare in our clinical work. However, they may progress quickly...
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Epididymal RNase T2 contributes to astheno-teratozoospermia and intergenerational metabolic disorder through epididymosome-sperm interaction
BackgroundThe epididymis is crucial for post-testicular sperm development which is termed sperm maturation. During this process, fertilizing ability...
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Distinct actions of testicular endocrine and lumicrine signaling on the proximal epididymal transcriptome
The epididymal function and gene expression in mammals are under the control of the testis. Sex steroids are secreted from the testis and act on the...
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The challenges in diagnosing isolated epididymal tuberculosis (TB) in an adolescent male: a case report
BackgroundGenitourinary tuberculosis (GUTB) is a common form of extrapulmonary TB (EPTB) in children. An example of GUTB is epididymal TB, which...
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Diagnostic nomogram to differentiate between epididymal tuberculosis and bacterial epididymitis
PurposeWe developed and validated a diagnostic nomogram for differentiating epididymal tuberculosis (TB) from bacterial epididymitis.
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Epididymal adenomatoid tumor: a case report and literature review
BackgroundAdenomatoid tumor is a very rare benign neoplasm of mesothelial origin affecting mainly female and male genital tracts. The diagnosis is...
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The developmental miR-17–92 cluster and the Sfmbt2 miRNA cluster cannot rescue the abnormal embryonic development generated using obstructive epididymal environment-producing sperm in C57BL/6 J mice
BackgroundSperm, during epididymal transit, acquires microRNAs(miRNAs), which are crucial for embryonic development. However, whether sperm miRNAs...
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The effect of epididymal sperm cryopreservation on neonatal birthweight following PESA-ICSI
PurposeTo compare the neonatal birthweight of singletons derived from ICSI cycles with fresh or frozen–thawed epididymal sperm in patients with...
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Epididymal cyst in children
The terms “epididymal cyst” and “spermatocele” are commonly used to describe the same entity, but, conversely, they are slightly different....
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Does ICSI outcome in obstructive azoospermia differ according to the origin of retrieved spermatozoa or the cause of epididymal obstruction? A comparative study
PurposeTo determine whether ICSI outcomes are affected by sperm source or genital tract inflammatory status.
MethodsA retrospective cohort study was...
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Wt1 haploinsufficiency induces browning of epididymal fat and alleviates metabolic dysfunction in mice on high-fat diet
Aims/hypothesisDespite a similar fat storing function, visceral (intra-abdominal) white adipose tissue (WAT) is detrimental, whereas subcutaneous WAT...
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A novel role for CFTR interaction with LH and FGF in azoospermia and epididymal maldevelopment caused by cryptorchidism
Cryptorchidism occurs frequently in children with cystic fibrosis. Among boys with cryptorchidism and abrogated mini-puberty, the development of the...
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Voluntary Exercise Attenuates Hyperhomocysteinemia, But Does not Protect Against Hyperhomocysteinemia-Induced Testicular and Epididymal Disturbances
The hyperhomocysteinemia (HHcy) is toxic to the cells and associated with several diseases. Clinical studies have shown changes in plasma...
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Panax notoginseng extract and total saponin suppress diet-induced obesity and endoplasmic reticulum stress in epididymal white adipose tissue in mice
BackgroundInvestigation on protective effects of Panax notoginseng against obesity and its related mechanisms is incomplete. Present study aimed to...
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Exposure to epididymal extracellular vesicles enhances immature sperm function and sustains vitality of cryopreserved spermatozoa in the domestic cat model
PurposeExtracellular vesicles (EVs) secreted by the epididymal epithelium transfer key factors to maturing spermatozoa. Using an in vitro system...
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Extracellular matrix interaction and apoptosis of the epididymal epithelium following hypothyroidism in Balb/C mouse
The role of the epididymis in post-testicular maturation of spermatozoa is to gain the potential to fertilize the ovum. It is well known that thyroid...
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The influence of Percoll® density gradient centrifugation before cryopreservation on the quality of frozen wisent (Bison bonasus) epididymal spermatozoa
BackgroundThe wisent ( Bison bonasus ) is a species that has undergone a population bottleneck. Homozygosity is prevalent within the population and...
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Bilateral secondary testicular, epididymal and spermatic cords carcinoma of prostatic origin: a case report and review of the literature
BackgroundProstatic carcinoma is emerging as the most common male malignancy in Nigeria and the second most common male cancer worldwide. Patients...
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Impact on using cryopreservation of testicular or epididymal sperm upon intracytoplasmic sperm injection outcome in men with obstructive azoospermia: a systematic review and meta-analysis
PurposeTo determine whether there was a significant impact on using cryopreservation of testicular or epididymal sperm upon the outcomes of...
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Quality of testicular spermatozoa improves with changes in composition of culture medium
BackgroundSpermatozoa retrieved from the testis and epididymis are deprived of the beneficial effects of seminal fluid. Thus applying an artificial...
