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Cytokine-based models for efficient differentiation between infection and cytokine release syndrome in patients with hematological malignancies
Although the efficacy of chimeric antigen receptor (CAR)-T cell therapy has been widely demonstrated, its clinical application is hampered by the...
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Analysis of Cytokine Profiles in Pediatric Myocarditis Multicenter Study
Acute myocarditis (AM) is an inflammatory disease of the heart muscle that can progress to fulminant myocarditis (FM), a severe and life-threatening...
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Age-related cytokine imbalance in the thymus in sudden infant death syndrome (SIDS)
BackgroundSudden infant death syndrome (SIDS) has been considered to be triggered by a combination of underlying immune dysregulation and infections....
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Reconstructing the cytokine view for the multi-view prediction of COVID-19 mortality
BackgroundCoronavirus disease 2019 (COVID-19) is a rapidly developing and sometimes lethal pulmonary disease. Accurately predicting COVID-19...
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Cytokine storm and translating IL-6 biology into effective treatments for COVID-19
As of May 3, 2023, the Coronavirus disease 2019 (COVID-19) pandemic has resulted in more than 760 million confirmed cases and over 6.9 million...
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Serum cytokine pattern in children with hemophagocytic lymphohistiocytosis
This study aimed to compare the serum levels of 34 cytokines of children with hemophagocytic lymphohistiocytosis (HLH) and explored the specific...
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Inflammatory cytokine levels and changes during omalizumab treatment in chronic spontaneous urticaria
While several studies have examined the role of T cells and related cytokines in the development of chronic spontaneous urticaria (CSU), there is a...
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Cytokine-responsive T- and NK-cells portray SARS-CoV-2 vaccine-responders and infection in multiple myeloma patients
Patients with multiple myeloma (MM) routinely receive mRNA-based vaccines to reduce COVID-19-related mortality. However, whether disease- and...
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CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo
BackgroundThe CytoSorb hemoadsorption device has been demonstrated to be capable of clearing inflammatory cytokines, but has not yet been shown to...
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Altered Cytokine Production in Human Intervillous Blood T Cells in Preeclampsia
Conventional and regulatory T cells (Treg) are dynamic mediators of maternal immune tolerance to the developing feto-placental unit. Functional...
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Modulation of heat shock protein expression and cytokine levels in MCF-7 cells through photodynamic therapy
In this study, we assess the impact of photodynamic therapy (PDT) using aluminum phthalocyanine tetrasulfonate (AlPcS 4 ) on the viability and cellular...
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Body mass index stratification enables cytokine-based prediction of ACPA status and Power-Doppler disease activity in rheumatoid arthritis
ObjectiveRheumatoid arthritis can be classified according to ACPA and RF status. ACPA status may be associated with other pathophysiological...
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Deregulation of cytokine affecting oral neutrophil subsets in oral cancer
The most prevalent form of leukocytes in human blood, neutrophils, is regarded as an essential part of the innate immune system and the body’s 1st...
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Tear fluid cytokine analysis: a non-invasive approach for assessing retinopathy of prematurity severity
PurposeTo determine whether there is a significant association between inflammatory cytokines in the tear fluid and the severity of Retinopathy of...
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Cell and cytokine analyses from bronchoalveolar lavage in non-critical COVID-19 pneumonia
Cell and cytokine analyses from bronchoalveolar lavage (BAL) in non-critically ill patients with COVID-19 pneumonia are poorly described. This study...
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Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7
CAR-T cell therapy has emerged as a breakthrough therapy for the treatment of relapsed and refractory hematologic malignancies. However, insufficient...
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Circulating Cytokine Levels and Cardiovascular Disease Risk Profile in Young Adult Offspring of Women with Type 1 Diabetes
IntroductionCytokines are key players in the development of both type 1 diabetes (T1D) and cardiovascular disease (CVD). Offspring of women with T1D...
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Cytokine release syndrome after bronchoalveolar lavage
BackgroundImmunosuppressed bone marrow transplant patients with pulmonary infiltrates routinely undergo bronchoscopy with bronchoalveolar lavage...
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Comparison of whole blood cytokine immunoassays for rapid, functional immune phenotyping in critically ill patients with sepsis
BackgroundSepsis is characterized by highly heterogeneous immune responses associated with a spectrum of disease severity. Methods that rapidly and...
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Cytokine profile in first-episode drug-naïve major depressive disorder patients with or without anxiety
ObjectiveIt is known that cytokines play a role in both depression and anxiety. This study aimed to compare the levels of multiple cytokines in...
