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Caffeine and neonatal acute kidney injury
Acute kidney injury is one of the most threatening diseases in neonates, with complex pathogenesis and limited treatment options. Caffeine is a...
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Caffeine pharmacokinetics following umbilical vein injection during delayed cord clamping in preterm lambs
BackgroundSpontaneous breathing during and after delayed cord clamping (DCC) stabilizes cardiopulmonary transition at birth. Caffeine stimulates...
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Administration time of caffeine in preterm infants: systematic review and meta-analysis
To assess the ideal time for caffeine administration in preterms, identifying its effects and safety. Study Design: Meta-analysis conducted including...
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Cardiovascular and cerebrovascular effects of caffeine maintenance in preterm infants during the transitional period
Background and aimCaffeine is routinely used for the prophylaxis of prematurity-related apnoeas. We aimed to evaluate the effect of caffeine...
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Prevalence of caffeine consumers, daily caffeine consumption, and factors associated with caffeine use among active duty United States military personnel
BackgroundAlthough representative data on caffeine intake in Americans are available, these data do not include US service members (SMs). The few...
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Effects of caffeine supplementation on anaerobic power and muscle activity in youth athletes
This study aimed to investigate the effects of caffeine ingestion on anaerobic performance and muscle activity in young athletes. In this randomized,...
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Caffeine for apnea and prevention of neurodevelopmental impairment in preterm infants: systematic review and meta-analysis
This systematic review and meta-analysis evaluated the evidence for dose and effectiveness of caffeine in preterm infants. MEDLINE, EMBASE, CINHAL...
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Threshold effects between caffeine intake and urine flow rate: a population-based cross-sectional study
PurposeThe potential benefits of caffeine intake are currently receiving much attention and exploration. Urine flow rate (UFR) is an objective index...
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Relationship between caffeine intake and thyroid function: results from NHANES 2007–2012
BackgroundModerate caffeine intake decreases the risk of metabolic disorders and all-cause mortality, and the mechanism may be related to its...
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Caffeine and kidney function at two years in former extremely low gestational age neonates
BackgroundExtremely low gestational age neonates (ELGANs) are at risk for chronic kidney disease. The long-term kidney effects of neonatal caffeine...
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The Role of the Combination Paracetamol/Caffeine in Treatment of Acute Migraine Pain: A Narrative Review
IntroductionThirty years ago, the first migraine-specific drugs (triptans) appeared. Today two new categories (gepants and ditans) are marketed for...
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Genetic investigation into the broad health implications of caffeine: evidence from phenome-wide, proteome-wide and metabolome-wide Mendelian randomization
BackgroundCaffeine is one of the most utilized drugs in the world, yet its clinical effects are not fully understood. Circulating caffeine levels are...
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Dietary caffeine intake is associated with favorable metabolic profile among apparently healthy overweight and obese individuals
BackgroundRecent studies have revealed some conflicting results about the health effects of caffeine. These studies are inconsistent in terms of...
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Maternal caffeine intake during pregnancy and the risk of delivering a small for gestational age baby: Kuopio Birth Cohort
PurposeHigh caffeine intake during pregnancy is associated with restricted fetal growth. We aimed to evaluate the association between maternal...
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Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization
BackgroundCaffeine exposure modifies the turnover of monoamine neurotransmitters, which play a role in several neuropsychiatric disorders. We...
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A phase I trial of caffeine to evaluate safety in infants with hypoxic-ischemic encephalopathy
ObjectiveCaffeine provides neuroprotection following hypoxic-ischemic injury in animals. We characterized the safety of escalating doses of caffeine...
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Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients
The plant defence compound caffeine is widely consumed as a performance enhancer in a sporting context, with potential benefits expected in both...
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Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies
Postoperative ileus (POI) after colorectal surgery is a major problem that affects both patient recovery and hospital costs highlighting the...
