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Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia
PurposeQuality of life (QoL), appetite, cachexia, and biomarkers [albumin, hemoglobin (Hb), neutrophils, lymphocytes, platelets, C-reactive protein...
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Medical imaging in cancer cachexia
Cancer cachexia, often referred to as “wasting syndrome,” is characterized by fatigue, weakness, and involuntary weight loss. This syndrome is...
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SEOM clinical guidelines for cancer anorexia-cachexia syndrome (2023)
Cancer-related anorexia-cachexia syndrome (CACS) is a debilitating condition afflicting up to 80% of advanced-stage cancer patients. Characterized by...
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Cancer cachexia: molecular mechanisms and treatment strategies
Muscle wasting is a consequence of physiological changes or a pathology characterized by increased catabolic activity that leads to progressive loss...
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Factors associated with multimodal care practices for cancer cachexia among registered dietitians
PurposeThis study aimed to determine factors associated with multimodal care practices for cancer cachexia among registered dietitians (RDs) working...
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Emerging markers of cancer cachexia and their relationship to sarcopenia
PurposeEmerging biomarkers of cancer cachexia and their roles in sarcopenia and prognosis are poorly understood. Baseline assessments of...
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Malnutrition and cachexia may affect death but not functional improvement in patients with sarcopenic dysphagia
PurposeTo investigate whether two factors, malnutrition and cachexia, affect swallowing function, activities of daily living (ADL), and death in...
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The roles of P-selectin in cancer cachexia
P -selectin, a cell adhesion molecule of the selectin family, is expressed on the surface of activated endothelial cells (ECs) and platelets. Binding...
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Cachexia Index in Patients with Gastrointestinal Cancer: A Systematic Review and Meta-Analysis
PurposeThe cachexia index is a novel biomarker of cancer cachexia. This systematic review and meta-analysis aimed to evaluate the prognostic impact...
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Malnutrition, sarcopenia and cachexia: exploring prevalence, overlap, and perceptions in older adults with cancer
BackgroundOlder adults with cancer are a growing population requiring tailored care to achieve optimum treatment outcomes. Their care is complicated...
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Relationship between cachexia and short physical performance battery scores in patients with heart failure attending comprehensive outpatient cardiac rehabilitation
Heart failure (HF) can cause metabolic imbalances, leading to anabolic resistance and increased energy expenditure, which often results in weight...
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Cancer-associated cachexia — understanding the tumour macroenvironment and microenvironment to improve management
Cachexia is a devastating, multifactorial and often irreversible systemic syndrome characterized by substantial weight loss (mainly of skeletal...
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Effect of cancer cachexia on first-line chemotherapy in patients with advanced pancreatic cancer: a claims database study in Japan
BackgroundCancer cachexia is a multifactorial syndrome leading to progressive functional impairment. How cachexia affects the treatment course of...
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The cachexia index is a prognostic factor for patients with recurrent pancreatic cancer
PurposeCancer cachexia leads to poor outcomes, especially for patients with advanced stage disease. The cachexia index (CXI), a novel biomarker for...
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Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers
Considerable advances in the investigation and management of oesophagogastric cancer have occurred over the last few decades. While the historically...
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Factors associated with early discontinuation of anamorelin in patients with cancer-associated cachexia
PurposeCancer-associated cachexia, a multifactorial syndrome involving loss of muscle mass and anorexia, is an unremitting problem for cancer...
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Anamorelin for the Treatment of Cancer Anorexia-Cachexia Syndrome
Purpose of ReviewThe following review will highlight the development of anamorelin to treat cancer anorexia-cachexia syndrome (CACS) including the...
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Jianpi Decoction Combined with Medroxyprogesterone Acetate Alleviates Cancer Cachexia and Prevents Muscle Atrophy by Directly Inhibiting E3 Ubiquitin Ligase
ObjectiveTo provide comprehensive evidence for the anti-cancer cachexia effect of Jianpi Decoction (JP) and to explore its mechanism of anti-cancer...
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LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia
BackgroundCancer cachexia is a deadly wasting syndrome that accompanies various diseases (including ~ 50% of cancers). Clinical studies have...
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Association of a newly developed Cancer Cachexia Score with survival in Stage I–III colorectal cancer
PurposeCancer cachexia, a complex multifactorial syndrome associated with sarcopenia, negatively affects the quality of life and survival in patients...