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Potential molecular targets and drugs for basement membranes-related intervertebral disk degeneration through bioinformatics analysis and molecular docking
BackgroundThrough bioinformatics analysis to identify the hub genes of Intervertebral disc degeneration (IVDD) associated with basement membranes...
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Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation
BackgroundExtraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have...
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Atypical anti-glomerular basement membrane disease with membranous hyperplasia: diagnostic challenges and treatment variability
This case report presents a detailed analysis of a 31-year-old male patient who presented with a complex array of clinical symptoms, including...
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ITGAM-mediated macrophages contribute to basement membrane damage in diabetic nephropathy and atherosclerosis
BackgroundDiabetic nephropathy (DN) and atherosclerosis (AS) are prevalent and severe complications associated with diabetes, exhibiting lesions in...
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Familial focal segmental glomerulosclerosis with Alport-like glomerular basement changes caused by paired box protein 2 gene variant
Paired box protein 2 ( PAX2 ) gene variant causes renal coloboma syndrome (MIM#120330). Further, they are associated with focal segmental...
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Remission induced by renal protective therapy in nephrotic syndrome with thin basement membrane in an older patient: a case report
BackgroundAdult nephrotic syndrome is a well-known kidney disease that causes heavy proteinuria, hypoalbuminemia, hypercholesterolemia, edema, and...
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A case report of atypical anti-glomerular basement membrane disease
BackgroundAnti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic necrotizing glomerulonephritis, with linear deposits of...
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Seven basement membrane-specific expressed genes are considered potential biomarkers for the diagnosis and treatment of diabetic nephropathy
AimsDiabetic nephropathy (DN) is a diabetes-related chronic vasculitis. DN diminishes kidney function over time and, of course, leads to end stage...
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Massage protects skeletal muscle from injury during long-term heavy-duty exercise via integrin β1 and laminin 2 channels of basement membrane
BackgroundMassage is widely used in exercise-induced skeletal muscle damage (EIMD). It has been proven that massage can improve the morphology and...
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Anti-glomerular basement membrane disease in children: a brief overview
Anti-glomerular basement membrane disease (Anti-GBM), previously known as Goodpasture syndrome, is an extremely rare cause of rapidly progressive...
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Effects of stretching on the basement membrane structure in the soleus muscle of Wistar rats
The basement membrane (BM), mainly composed of collagen IV, plays an important role in the maintenance, protection, and recovery of muscle fibers....
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A comparative study of human glomerular basement membrane thickness using direct measurement and orthogonal intercept methods
IntroductionHere we report estimates of glomerular basement membrane (GBM) thickness in the Brazilian population performed using direct (DM) and...
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Anti-glomerular basement membrane disease developing 3 years after the development of Sweet syndrome and 1 year after the development of anti-neutrophil cytoplasmic antibody-associated vasculitis: a case report
A 73-year-old Japanese woman, with a history of Sweet syndrome diagnosed 3 years earlier and anti-myeloperoxidase (MPO) antibody anti-neutrophil...
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SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report
BackgroundAnti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and...
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Acquired aplastic anemia complicated with anti-glomerular basement membrane disease successfully treated with immunosuppressive therapy: a case report
BackgroundAplastic anemia (AA) is a rare but fatal disorder characterized by pancytopenia due to bone marrow hypoplasia. Anti-glomerular basement...
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Complexities of the glomerular basement membrane
The glomerular basement membrane (GBM) is a key component of the glomerular capillary wall and is essential for kidney filtration. The major...
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SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how...
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The extracellular matrix complexity of idiopathic epiretinal membranes and the bilaminar arrangement of the associated internal limiting membrane in the posterior retina
PurposeTo study the composition of the internal limiting membrane (ILM) of the retina, the extracellular matrix (ECM) of idiopathic epiretinal...
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Glomerulonephritis associated with systemic sclerosis: a case report
BackgroundSystemic sclerosis is a multiorgan autoimmune disease that can overlap with other rheumatologic disorders; however, co-occurrence with...
