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Hotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000–2022
BackgroundAlzheimer's disease is one common type of dementia. Numerous studies have suggested a correlation between Alzheimer's disease and...
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Technical Review of Clinical Outcomes Assessments Across the Continuum of Alzheimer's Disease
IntroductionInsight into the relationship between concepts that matter to the people affected by Alzheimer’s disease (AD) and the clinical outcome...
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Early prediction of Alzheimer's disease using convolutional neural network: a review
In this paper, a comprehensive review on Alzheimer's disease (AD) is carried out, and an exploration of the two machine learning (ML) methods that...
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Is Aducanumab treatment developed to prevent progression of Alzheimer's disease cost-effective in Turkey?
BackgroundAlzheimer's Disease (AD), the most common type of dementia, is a chronic, progressive, and neurodegenerative brain discomfort that causes...
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Immunological evaluation of patients with Alzheimer's disease based on mitogen-stimulated cytokine productions and mitochondrial DNA indicators
BackgroundBased on its objective characteristics, laboratory markers have always been the research direction of clinical diagnosis and assessment of...
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Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics
Two anti-amyloid monoclonal antibodies (MABs)—lecanemab (Leqembi ® ) and aducanumab (Aduhelm ® )—have been approved in the USA for the treatment of...
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Phosphodiesterase-5 inhibitors use and the risk of alzheimer's disease: a systematic review and meta-analysis
BackgroundThe management of Alzheimer's disease (AD) poses considerable challenges, necessitating the pursuit of innovative therapeutic approaches....
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Advanced molecular therapies for neurological diseases: focus on stroke, alzheimer's disease, and parkinson's disease
Neurological diseases (NDs) are one of the leading causes of disability and the second leading cause of death globally. Among these stroke,...
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Alzheimer's Disease and the Eye
This book is a compendium of the worldwide studies of Alzheimer’s disease utilizing the eye as a biomarker, or as a treatment method, that are...
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AI for the prediction of early stages of Alzheimer's disease from neuroimaging biomarkers – A narrative review of a growing field
ObjectivesThe objectives of this narrative review are to summarize the current state of AI applications in neuroimaging for early Alzheimer's disease...
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Patterns of use of symptomatic treatments for Alzheimer's disease dementia (AD)
BackgroundSymptomatic treatment for Alzheimer's disease (AD) dementia could temporarily slow symptom worsening and improve the quality of life for...
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Causal relationships between delirium and Alzheimer's disease: a bidirectional two-sample Mendelian randomization study
BackgroundPrevious observational studies have reported that delirium has an association with an increased risk of Alzheimer's disease (AD), and that...
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Bayesian estimation for the accuracy of three neuropsychological tests in detecting Alzheimer's disease and mild cognitive impairment: a retrospective analysis of the ADNI database
BackgroundThe neuropathological confirmation serves as the gold standard for diagnosing Alzheimer's disease (AD), but it is usually not available to...
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Design of a Non-Interventional Study to Assess Neurologists’ Perspectives and Pharmacological Treatment Decisions in Early Alzheimer's Disease
IntroductionThe current therapeutic landscape of Alzheimer's disease (AD) is evolving rapidly. Our treatment options include new anti-amyloid-β...
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Sleep duration, genetic susceptibility, and Alzheimer's disease: a longitudinal UK Biobank-based study
BackgroundAlzheimer's disease (AD) is the most frequently occurring type of dementia. Concurrently, inadequate sleep has been recognized as a public...
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Cerebrospinal fluid NPTX2 changes and relationship with regional brain metabolism metrics across mild cognitive impairment due to Alzheimer's disease
BackgroundNeuronal pentraxin-2 (NPTX2), crucial for synaptic functioning, declines in cerebrospinal fluid (CSF) as cognition deteriorates. The...
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Disease severity and mortality in Alzheimer's disease: an analysis using the U.S. National Alzheimer’s Coordinating Center Uniform Data Set
BackgroundEvidence on the relative risk of death across all stages of Alzheimer’s disease (AD) is lacking but greatly needed for the evaluation of...
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Diagnostic performance of MRI radiomics for classification of Alzheimer's disease, mild cognitive impairment, and normal subjects: a systematic review and meta-analysis
BackgroundAlzheimer's disease (AD) is a debilitating neurodegenerative disease. Early diagnosis of AD and its precursor, mild cognitive impairment...
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Contribution of Iranian researchers in Alzheimer's disease research: A 10 years scientometric analysis
BackgroundAlzheimer's disease is the most common form of dementia and is a rising issue for global health. Iran is struggling with a growing number...
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Effective dosage and mode of exercise for enhancing cognitive function in Alzheimer's disease and dementia: a systematic review and Bayesian Model-Based Network Meta-analysis of RCTs
ObjectiveResearch the dose–response relationship between overall and certain types of exercise and cognitive function in older adults with...
