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A critical role of brain network architecture in a continuum model of autism spectrum disorders spanning from healthy individuals with genetic liability to individuals with ASD
Studies have shown cortical alterations in individuals with autism spectrum disorders (ASD) as well as in individuals with high polygenic risk for...
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Common and distinct cortical thickness alterations in youth with autism spectrum disorder and attention-deficit/hyperactivity disorder
BackgroundAutism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders with overlapping...
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Adverse effects of perinatal illness severity on neurodevelopment are partially mediated by early brain abnormalities in infants born very preterm
BackgroundWe sought to determine the mediating effects of magnetic resonance imaging (MRI) biomarkers at term gestation on the relationship between...
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Social isolation and the brain: effects and mechanisms
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide reduction in social interaction, which is associated with many...
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Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis
Reliable mapping of system-level individual differences is a critical first step toward precision medicine for complex disorders such as...
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Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental childhood-onset disorder characterized by a persistent...
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Morgellons disease: a narrative review
Morgellons disease is characterized by the persistent delusion of skin infestation, ultimately inflicting wounds and impairing quality of life. There...
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Functional Connectivity of Nucleus Accumbens Is Associated with Lifelong Premature Ejaculation in Male Adults
PurposeEjaculation represents a crucial component of sexual behavior in men, which is involved in reward functions of certain brain areas including...
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Effects of ambient air pollution, fresh fruit and vegetable intakes as well as maternal psychosocial stress on the outcome of newborn otoacoustic emission hearing screening
BackgroundNewborn hearing screening results indicated that more than 40% of the detected infants had no recognized risk factors. To determine whether...
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Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit
A summit held March 2023 in Scottsdale, Arizona (USA) focused on the intronic hexanucleotide expansion in the C9ORF72 gene and its relevance in...
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Excessive interstitial free-water in cortical gray matter preceding accelerated volume changes in individuals at clinical high risk for psychosis
Recent studies show that accelerated cortical gray matter (GM) volume reduction seen in anatomical MRI can help distinguish between individuals at...
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Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh
BackgroundThere are limited data on the impact of perinatal inflammation on child neurodevelopment in low-middle income countries and among...
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Effects of neurodevelopmental risk factors on brainstem maturation in premature infants
BackgroundInterpeak latencies (IPL), as measured by the auditory brainstem-evoked responses (ABR) test, represent the conduction time, and therefore...
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Adolescent substance use initiation and long-term neurobiological outcomes: insights, challenges and opportunities
The increased frequency of risk taking behavior combined with marked neuromaturation has positioned adolescence as a focal point of research into the...
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Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial
A promising new treatment approach for major depressive disorder (MDD) targets the microbiota-gut-brain (MGB) axis, which is linked to physiological...
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Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium
Using machine learning, we recently decomposed the neuroanatomical heterogeneity of established schizophrenia to discover two volumetric subgroups—a...
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Parsing brain-behavior heterogeneity in very preterm born children using integrated similarity networks
Very preterm birth (VPT; ≤32 weeks’ gestation) is associated with altered brain development and cognitive and behavioral difficulties across the...
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Brain abnormalities in myelomeningocele patients
BackgroundMyelomeningocele (MMC) is often related to hydrocephalus and Chiari malformation (CM) type 2; however, other brain abnormalities have been...
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Identification of brain cell types underlying genetic association with word reading and correlated traits
Neuroimaging studies implicate multiple cortical regions in reading ability/disability. However, the neural cell types integral to the reading...
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Efficient Claustrum Segmentation in T2-weighted Neonatal Brain MRI Using Transfer Learning from Adult Scans
PurposeIntrauterine claustrum and subplate neuron development have been suggested to overlap. As premature birth typically impairs subplate neuron...
