Search
Search Results
-
Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation
There is concern regarding the impact of selective serotonin reuptake inhibitors (SSRIs) on suicidal behaviour. Using the target trial framework, we...
-
Association between CYP metabolizer phenotypes and selective serotonin reuptake inhibitors induced weight gain: a retrospective cohort study
BackgroundPrescription medications such as selective serotonin reuptake inhibitors (SSRIs), commonly used to treat depression, are associated with...
-
Mixed lymphocytic and collagenous inflammation of the entire gastrointestinal tract under therapy with serotonin and norepinephrine reuptake inhibitors
Drug-induced injury to the gastrointestinal tract has gained growing significance in recent years, and the list of causative medications keeps...
-
Association between brain serotonin 4 receptor binding and reactivity to emotional faces in depressed and healthy individuals
Brain serotonergic (5-HT) signaling is posited to modulate neural responses to emotional stimuli. Dysfunction in 5-HT signaling is implicated in...
-
The relationship between dose and serotonin transporter occupancy of antidepressants—a systematic review
Brain imaging techniques enable the visualization of serotonin transporter (SERT) occupancy as a measure of the proportion of SERT blocked by an...
-
Ventral prefrontal serotonin 1A receptor binding: a neural marker of vulnerability for mood disorder and suicidal behavior?
Mood disorders and suicidal behavior have moderate heritability and are associated with altered corticolimbic serotonin 1A receptor (5-HT 1A ) brain...
-
Molecular signature of excessive female aggression: study of stressed mice with genetic inactivation of neuronal serotonin synthesis
Aggression is a complex social behavior, critically involving brain serotonin (5-HT) function. The neurobiology of female aggression remains elusive,...
-
Serotonin transporter availability increases in patients recovering from a depressive episode
Molecular imaging studies have shown low cerebral concentration of serotonin transporter in patients suffering from depression, compared to healthy...
-
The use of serotonin reuptake inhibitors increases the risk of bleeding in patients with assist devices
BackgroundBleedings are frequent and dreaded complications in heart failure patients with ventricular assist devices (VAD). Serotonin reuptake...
-
Severity of neonatal opioid withdrawal syndrome with prenatal exposure to serotonin reuptake inhibitors
ObjectiveTo evaluate the severity of neonatal opioid withdrawal syndrome (NOWS) in infants prenatally exposed to medications for opioid use disorder...
-
Measurement of changes in endogenous serotonin level by positron emission tomography with [18F]altanserin
ObjectivePositron emission tomography (PET) has been used to investigate changes in the concentration of endogenous neurotransmitters. Recently, this...
-
Insulin modulates emotional behavior through a serotonin-dependent mechanism
Type-2 Diabetes (T2D) is characterized by insulin resistance and accompanied by psychiatric comorbidities including major depressive disorders (MDD)....
-
Acute psychosis and serotonin syndrome in the setting of “Triple-C” overdose: a case report
BackgroundOver-the-counter medication overdose is a difficult diagnostic challenge for many physicians as common drug screening assays cannot detect...
-
Impact of chosen cutoff on response rate differences between selective serotonin reuptake inhibitors and placebo
Response defined as a 50% reduction in the sum score of the Hamilton Depression Rating Scale (HDRS-17-sum) is often used to assess the efficacy of...
-
Tryptophan and serotonin levels as potent biomarkers in diabetes mellitus complications: a new approach of diagnostic role
ObjectiveAlterations in the serotonergic system were verified to act a role in the pathogenesis of altered neurological and psychiatric diseases. In...
-
Sudden infant death syndrome revisited: serotonin transporter gene, polymorphisms and promoter methylation
BackgroundBased on findings in the brain stems of SIDS victims, the serotonin transporter (5-HTT) gene has been discussed to be associated with SIDS.
... -
Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1
BackgroundTriple-negative breast cancer (TNBC) is an aggressive type of breast cancer and associated with poor prognosis and shorter survival due to...
