Search
Search Results
-
Spatiotemporal patterns of brain iron-oxygen metabolism in patients with Parkinson’s disease
ObjectivesIron deposition and mitochondrial dysfunction are closely associated with the genesis and progression of Parkinson’s disease (PD). This...
-
Transcranial alternating current stimulation improves quality of life in Parkinson’s disease: study protocol for a randomized, double-blind, controlled trial
BackgroundThe neural cells in the brains of patients with Parkinson’s disease (PWP) display aberrant synchronized oscillatory activity within the...
-
Application of single wrist-wearable accelerometry for objective motor diary assessment in fluctuating Parkinson’s disease
Advanced Parkinson’s disease (PD) is characterized by motor fluctuations including unpredictable oscillations remarkably impairing quality of life....
-
Cerebellar and cerebral white matter changes in Parkinson’s disease with resting tremor
PurposeCerebellum modulates the amplitude of resting tremor in Parkinson’s disease (PD) via cerebello-thalamo-cortical (CTC) circuit. Tremor-related...
-
On the Optimal Diagnosis and the Evolving Role of Pimavanserin in Parkinson’s Disease Psychosis
Parkinson’s disease (PD) is associated with the development of psychosis (PDP), including hallucinations and delusions, in more than half of the...
-
Radiomics score derived from T1-w/T2-w ratio image can predict motor symptom progression in Parkinson’s disease
ObjectivesTo clarify the association between a radiomics score (Rad-score) derived from T1-weighted signal intensity to T2-weighted signal intensity...
-
A biological characterization of patients with postmenopausal Parkinson’s disease
Menopause increases the risk for Parkinson’s disease (PD), although the underlying biological mechanisms have not been established in patients. Here,...
-
Evaluation of a co-designed Parkinson’s awareness audio podcast for undergraduate nursing students in Northern Ireland
BackgroundParkinson’s Disease (PD) is a common neurological condition that often causes stiffness, tremor and slow movement. People living with PD...
-
Targeting sleep and the circadian system as a novel treatment strategy for Parkinson’s disease
There is a growing appreciation of the wide range of sleep–wake disturbances that occur frequently in Parkinson’s disease. These are known to be...
-
Group-based exercise for Parkinson’s: a qualitative study of participants and partners’ perceptions of an exercise class delivered through a community-university collaboration
BackgroundCommunity-based exercise programmes (CBEPs) offer a practical and viable approach to providing people with Parkinson’s disease (PwP) the...
-
Effects of rasagiline combined with levodopa and benserazide hydrochloride on motor function and homocysteine and IGF-1 levels in elderly patients with Parkinson’s disease
BackgroundDuring the course of their illness, people with Parkinson’s disease may see changes in their insulin-like growth factor (IGF-1) and serum...
-
Acoustical and Perceptual Analysis of Voice in Individuals with Parkinson’s Disease
Parkinson’s disease is a neurodegenerative disorder that affects motor efficiency which is also required for voice production. Voice is part of the...
-
Impulse control disorders in Parkinson’s disease: a retrospective analysis of 1824 patients in a 12-year period
ObjectiveThis study aims to clinically evaluate the impulse control disorders (ICDs) encountered in treating Parkinson’s disease.
Method ... -
Creative thinking and cognitive estimation in Parkinson’s disease
BackgroundPatients with Parkinson’s disease (PD) have been reported to exhibit unusual bouts of creativity (e.g., painting, writing), in particular...
-
Body composition, Falls, and Freezing of Gait in Parkinson’s Disease: Gender-Specific Effects
BackgroundPostural instability and gait difficulties (PIGD) are a significant cause of mobility loss and lower quality of life in Parkinson’s disease...
-
Autophagy markers, cognitive deficits and depressive symptoms in Parkinson’s disease
AbstractDepressive symptoms are common in Parkinson’s disease (PD). The relationships between autophagy and PD or depression have been documented....
-
Facial emotion expressivity in patients with Parkinson’s and Alzheimer’s disease
Parkinson’s disease (PD) and Alzheimer’s disease (AD) are neurodegenerative disorders with some overlapping clinical features. Hypomimia (reduced...
-
Electrophysiological signatures of anxiety in Parkinson’s disease
Anxiety is a common non-motor symptom in Parkinson’s disease (PD) occurring in up to 31% of the patients and affecting their quality of life. Despite...
-
Motor and non-motor outcome in tremor dominant Parkinson’s disease after MR-guided focused ultrasound thalamotomy
Background and objectivesMagnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging technique for the treatment of severe,...
-
The prevalence of sarcopenia in Parkinson’s disease and related disorders- a systematic review
BackgroundThe prevalence of sarcopenia (reduced skeletal muscle strength and mass), Parkinson’s disease (PD) and Parkinson’s related disorders (PRD)...
