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Management of male factor infertility: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS)
PurposeInfertility affects 15–20% of couples and male factors are present in about half of the cases. For many aspects related to the diagnostic and...
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Associations of obesity and body shape with erythrocyte and reticulocyte parameters in the UK Biobank cohort
BackgroundObesity is associated with type 2 diabetes mellitus and chronic low-grade inflammation. Although chronic inflammatory conditions and...
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Preoperative topical estrogen application in the management of hypospadias: a systematic review
Local estrogen therapy has been explored as an alternative to conventional testosterone therapy in children requiring urethroplasty for hypospadias....
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PTH receptor signalling, osteocytes and bone disease induced by diabetes mellitus
Basic, translational and clinical research over the past few decades has provided new understanding on the mechanisms by which activation of the...
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Neurological care for LGBT+ people
Sexual and gender minority (LGBT+) people face unique health disparities that must be considered by health-care providers to ensure equitable and...
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Type 2 Diabetes Mellitus and Menopausal Hormone Therapy: An Update
During menopausal transition, various phenotypical and metabolic changes occur, affecting body weight, adipose tissue distribution and energy...
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Prenatally detected six duplications at Xp22.33-p11.22: a case report
BackgroundThe discrepancy between the results of cytogenetics and the results of chromosome microarray analysis (CMA) has often led to confusion over...
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Impact of menopause on relapse rate and disability level in patients with multiple sclerosis (MS): a systematic review and meta-analysis
BackgroundMenopause is a physiologic phase in women’s lives. Findings regarding multiple sclerosis (MS) course through menopause are diverse. So, we...
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Dynamic Molding of Cleft Nasal Cartilage in Unilateral Complete Cleft Lip and Palate Using Simple Segmented NAM
ObjectiveNasal morphology remodeling by nasoalveolar molding (NAM) before primary lip repair gives better post-surgery outcomes. However, traditional...
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Gender differences and risk of readmission in hospitalizations with a diagnosis of psychotic spectrum disorders
BackgroundGender differences in psychosis are a topic that has been studied considering different aspects. Although some available evidence would...
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Drug-Induced Sexual Dysfunction: An Analysis of Reports to a National Pharmacovigilance Database
IntroductionSexual dysfunction (SD) is a problem that can affect any phase of the sexual response cycle (such as sexual desire, arousal and orgasm)...
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Pathophysiology and risk factors of peripartum cardiomyopathy
Peripartum cardiomyopathy (PPCM) is a potentially fatal form of idiopathic heart failure with variable prevalence across different countries and...
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Hormonal Differences Between Women and Men, Their Consequences on Addiction to Substances and Considerations on the Therapeutic Approach
Purpose of the reviewA search of scientific papers has been carried out to investigate sex differences in drug abuse and to understand the underlying...
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Day and night heart rate variability using 24-h ECG recordings: a systematic review with meta-analysis using a gender lens
PurposeIncreasing evidence demonstrates that gender-related factors, and not only biological sex, are relevant in the physiological and...
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Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy
Glucagon-like peptide-1 (GLP-1) receptor agonists are established pharmaceutical therapies for the treatment of type 2 diabetes and obesity. They...
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Neuroactive steroids in the neuroendocrine control of food intake, metabolism, and reproduction
Neuroactive steroids are a type of steroid hormones produced within the nervous system or in peripheral glands and then transported to the brain to...
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Sarcopenia is linked to higher levels of B-type natriuretic peptide and its N-terminal fragment in heart failure: a systematic review and meta-analysis
AimsSarcopenia is linked to impaired physical function and exercise tolerance. The aim of this systematic review and meta-analysis was to examine the...
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Fertility-Sparing Treatment for Atypical Endometrial Hyperplasia and Endometrial Cancer: A Cochrane Systematic Review Protocol
IntroductionEndometrial cancer is the fifth most common cancer in women and atypical endometrial hyperplasia is a precancerous lesion. Obesity is an...
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Prevalence of rheumatoid arthritis in Greece: results from the national health examination survey EMENO
Rheumatoid arthritis (RA) is considered the most common form of autoimmune arthritis. The disease’s prevalence is around 0.5–1% worldwide, but it...