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Two decades of research on the role of diet in Alzheimer’s disease (2003–2023): a bibliometric and visual analysis based on CiteSpace
BackgroundIn recent years, the impact of diet on Alzheimer's disease (AD) as a modifiable lifestyle has attracted widespread attention. We aimed to...
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Association of pro-inflammatory diet with increased risk of all-cause dementia and Alzheimer's dementia: a prospective study of 166,377 UK Biobank participants
BackgroundIncreasing evidence suggests an association between pro-inflammatory diets and cognitive function. However, only a few studies based on...
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Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes
Parkinson´s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of symptoms is...
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Genetic forms of tauopathies: inherited causes and implications of Alzheimer’s disease-like TAU pathology in primary and secondary tauopathies
Tauopathies are a heterogeneous group of neurologic diseases characterized by pathological axodendritic distribution, ectopic expression, and/or...
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Artificial Intelligence on FDG PET Images Identifies Mild Cognitive Impairment Patients with Neurodegenerative Disease
The purpose of this project is to develop and validate a Deep Learning (DL) FDG PET imaging algorithm able to identify patients with any...
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Potential role of recombinant growth differentiation factor 11 in Alzheimer’s disease treatment
Alzheimer's disease (AD) is a neurodegenerative disease closely related to the accumulation of beta-amyloid (Aβ) plaques. Growth differentiation...
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Predicting the efficacy of donepezil intervention in Alzheimer’s disease patients using regional homogeneity in the inferior orbitofrontal cortex
BackgroundAlthough donepezil is a commonly used drug for treating Alzheimer's disease (AD), the mechanisms by which it affects patients’ functional...
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Psychological distress among family caregivers of persons with Alzheimer’s disease and related dementias in Uganda
BackgroundAlzheimer's disease and related dementias (ADRD) present growing global health challenges, especially in aging populations, such as Uganda....
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PSEN2 and ABCA7 variants causing early-onset preclinical pathological changes in Alzheimer's disease: a case report and literature review
BackgroundAlzheimer’s disease (AD) is a debilitating and highly heritable neurodegenerative disease. Early-onset AD (EOAD) was defined as AD...
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From lab bench to hope: a review of gene therapies in clinical trials for Parkinson’s disease and challenges
Parkinson's disease (PD) is a chronic neurological disorder that is identified by a characteristic combination of symptoms such as bradykinesia,...
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Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification
Novel agents addressing non-amyloid, non-tau targets in Alzheimer’s Disease (AD) comprise 70% of the AD drug development pipeline of agents currently...
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RETRACTED ARTICLE: Polyphenols from Conyza dioscoridis (L.) ameliorate Alzheimer’s disease- like alterations through multi-targeting activities in two animal models
BackgroundRecent investigations suggested that anticancer agents may inhibit the progression of Alzheimer's disease (AD) pathology. Conyza dioscoridis ...
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Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations
BackgroundSolanum lycopersicum Linn. (Tomato, Family Solanaceae) is one of the fruits that are most consumed worldwide. The current research intends...
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Neurophysiological correlates of altered time awareness in Alzheimer’s disease and frontotemporal dementia
BackgroundAlterations in time awareness have been reported in dementia, particularly in Alzheimer's disease (AD) and frontotemporal dementia (FTD)....
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Clinical importance in Alzheimer’s disease: effects of anchor agreement and disease severity
ObjectivesMethods of evaluating clinically meaningful decline are critical in research on Alzheimer’s disease. A common method of quantifying...
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Relieving care burden and promoting health-related quality of life for family caregivers of elderly people with Alzheimer’s disease via an empowerment program
BackgroundEffective strategies should be adopted to reduce care burden (CB) and improve health-related quality of life (HRQoL) in family caregivers...
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The first quick olfactory test specific for Alzheimer’s disease and French culture
PurposeOlfactory identification disorder is considered a promising early biomarker of Alzheimer's disease (AD). The QUICK TODA2 can be used as a...
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Clinical characteristics of patients with suspected Alzheimer’s disease within a CSF Aß-ratio grey zone
BackgroundThe AT(N) research framework for Alzheimer's disease (AD) remains unclear on how to best deal with borderline cases. Our aim was to...
