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Drug interaction between a selective serotonin reuptake inhibitor and a triptan leading to serotonin toxicity: a case report and review of the literature
BackgroundSerotonin toxicity is a known side effect of selective serotonin reuptake inhibitors and has previously also been described as a possible...
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Selective Serotonin Reuptake Inhibitors for the Treatment of Depression in Parkinson’s Disease: A Systematic Review and Meta-Analysis
BackgroundAlthough selective serotonin reuptake inhibitors (SSRIs) are usually considered safe to use in patients with Parkinson’s disease (PD),...
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Serotonin-releasing agents with reduced off-target effects
Increasing extracellular levels of serotonin (5-HT) in the brain ameliorates symptoms of depression and anxiety-related disorders, e.g., social...
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Efficacy, safety, and tolerability of serotonin-norepinephrine reuptake inhibitors in controlling ADHD symptoms: a systematic review and meta-analysis
IntroductionThe aim of this study is to assess the effectiveness of serotonin-norepinephrine reuptake inhibitors (SNRIs) in managing ADHD symptoms...
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The complex clinical response to selective serotonin reuptake inhibitors in depression: a network perspective
The clinical response to selective serotonin reuptake inhibitors (SSRIs) in depression takes weeks to be fully developed and is still not entirely...
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The Serotonin-Immune Axis in Preeclampsia
Purpose of ReviewTo review the literature and detail the potential immune mechanisms by which hyperserotonemia may drive pro-inflammation in...
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Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit
BackgroundSerotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated...
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Serotonin-positive neuroendocrine neoplasm with pancreatic ductal dilation in which cytological immunostaining contributed to the diagnosis
A 52-year-old man was transported via an ambulance because of syncope and the passage of tarry stools, which had been noted the previous day. He was...
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ABCB1 variants and sex affect serotonin transporter occupancy in the brain
Strategies to personalize psychopharmacological treatment promise to improve efficacy and tolerability. We measured serotonin transporter occupancy...
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Selective Serotonin Reuptake Inhibitors (SSRIs) in Pregnancy: An Updated Review on Risks to Mother, Fetus, and Child
Purpose of ReviewTo provide an updated summary and appraisal of work from 2019 to 2022 examining risks of selective serotonin reuptake inhibitor...
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A systematic review and meta-analysis on the efficacy outcomes of selective serotonin reuptake inhibitors in depression in Alzheimer’s disease
BackgroundDepressive symptoms are the most common neuropsychiatric symptoms in patients with Alzheimer’s disease (AD). However, despite being common,...
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Sleep Apnea and Serum Serotonin Level Pre- and Post-PAP Therapy: A Preliminary Study
IntroductionThe high prevalence of obstructive sleep apnea (OSA), which impairs quality of life for numerous patients and leads to various OSA...
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TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan hydroxylase 1 concentrations in acute pancreatitis patients
BackgroundThe role of serotonin and its metabolic pathway in proper functioning of the pancreas has not been thoroughly investigated yet in acute...
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Serum amyloid P component (SAP) modulates antidepressant effects through promoting membrane insertion of the serotonin transporter
Serum amyloid P component (SAP) is a universal constituent of human amyloid deposits including those in Alzheimer’s disease. SAP has been observed to...
