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The role of sex and gender in the diagnosis and treatment of lung cancer: the 6th ICAPEM Annual Symposium
The incidence and mortality of lung cancer in women are rising, with both increasing by 124% between 2003 and 2019. The main risk factor for lung...
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Sex—the most underappreciated variable in research: insights from helminth-infected hosts
The sex of a host affects the intensity, prevalence, and severity of helminth infection. In many cases, one sex has been found to be more susceptible...
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The curious case of testicular descent: factors controlling testicular descent with a note on cryptorchidism
BackgroundThe testicular descent is a uniquely complex process depending upon multiple factors like growth and reorganisation of the specific gonadal...
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Incidence of hypertension in young transgender people after a 5-year follow-up: association with gender-affirming hormonal therapy
In order to assess the risk of hypertension development, we performed a retrospective analysis of the clinical records of consecutive transgender...
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Association between dehydroepiandrosterone sulphate levels at 7 years old and bone mineral density at 10 years old: a prospective cohort study
We aimed to explore the effect of dehydroepiandrosterone sulphate (DHEAS) at age 7 on areal bone mineral density (aBMD) at age 10 and to distinguish...
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Estetrol/Drospirenone: A Review in Oral Contraception
Estetrol/drospirenone is a combined oral contraceptive (COC) with a plant-synthesised foetal oestrogen (estetrol) and a well-established progestin...
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Sex differences in movement disorders
In a range of neurological conditions, including movement disorders, sex-related differences are emerging not only in brain anatomy and function, but...
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Skeletal disorders associated with the growth hormone–insulin-like growth factor 1 axis
Growth hormone (GH) and insulin-like growth factor 1 (IGF1) are important regulators of bone remodelling and metabolism and have an essential role in...
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Pregnancy and the Control of Epileptic Seizures: A Review
Over the past 50 years, published studies have provided quantitative data on the control of epileptic seizures during pregnancy. The studies have...
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Sex-specific association between carotid atherosclerosis and fundus arteriosclerosis in a Chinese population: a retrospective cross-sectional study
ObjectivesVascular stiffening is highly predictive of major adverse cardiovascular events. It is not clear whether microangiopathy, such as fundus...
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Longitudinal assessment of classic and 11-oxygenated androgen concentrations and their association with type 2 diabetes mellitus development: the Tromsø study
AimWe aimed to investigate changes in pre-diagnostic concentrations of classic and 11-oxygenated androgens in type 2 diabetes (T2DM) cases and...
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Genetics, pathobiology and therapeutic opportunities of polycystic liver disease
Polycystic liver diseases (PLDs) are inherited genetic disorders characterized by progressive development of intrahepatic, fluid-filled biliary cysts...
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Sex, gender, and subclinical hypertensiveorgan damage—heart
Hypertension-mediated organ damage (HMOD) at cardiac level include a variety of abnormal phenotypes of recognized adverse prognostic value. Although...
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Global epidemiology of rheumatoid arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the joints. The prevalence of RA varies globally, with...