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  1. Immediate fortification of human milk with a bovine milk-derived human milk fortifier in very low birth weight infants: a randomized clinical trial

    Objective

    Double-blind randomized control trial of early addition of a bovine milk-derived human milk fortifier (HMF) in very low birth weight (VLBW)...

    Zanna Wynter, Jane Anne Gorham, ... Brian K. Stansfield in Journal of Perinatology
    Article Open access 09 May 2024
  2. Recent Developments in the Regulation of Heritable Human Genome Editing

    In 2018, the Chinese scientist He Jiankui presented his research at the Second International Summit on Human Genome Editing in Hong Kong. While it...

    Article Open access 01 March 2024
  3. Illegitimate work tasks: an investigation of psychometric properties of the Swedish version of the BITS instrument and its suitability in human versus ‘non-human’ service occupations

    Background

    Illegitimate tasks, i.e. working tasks that are perceived as unnecessary or unreasonable, are commonly measured by the Bern Illegitimate...

    Johanna Stengård, Constanze Leineweber, Hanne Berthelsen in BMC Public Health
    Article Open access 18 July 2024
  4. Human preterm colostrum stimulates outgrowth in neurogenic tissue

    Background

    The olfactory bulb has a key role for nasal delivery of drugs to the brain by its access from the nasal mucosa and its connection to the...

    Julian Kaps, Veronica S. Georgieva, ... Titus Keller in Pediatric Research
    Article Open access 11 July 2023
  5. A roadmap for delivering a human musculoskeletal cell atlas

    Advances in single-cell technologies have transformed the ability to identify the individual cell types present within tissues and organs. The...

    Mathew Baldwin, Christopher D. Buckley, ... Sarah Snelling in Nature Reviews Rheumatology
    Article 05 October 2023
  6. Fungal Sensitization and Human Allergic Disease

    Purpose of the Review

    Fungal sensitizations have been associated with hypersensitivity reactions with variable levels of evidence available to link...

    Scout Treadwell, Maxwell Green, ... John C Carlson in Current Allergy and Asthma Reports
    Article 05 April 2024
  7. Mouse IgA modulates human gut microbiota with inflammatory bowel disease patients

    Background

    The imbalance of commensal bacteria is called dysbiosis in intestinal microflora. Secreted IgA in the intestinal lumen plays an important...

    Keishu Takahashi, Naoki Morita, ... Reiko Shinkura in Journal of Gastroenterology
    Article Open access 14 June 2024
  8. Human Brain Organoid Research and Applications: Where and How to Meet Legal Challenges?

    An ethical and legal framework is needed to regulate the rapidly developing human brain organoid research field properly. However, considering the...

    M. Kataoka, T.-L. Lee, T. Sawai in Journal of Bioethical Inquiry
    Article Open access 05 July 2024
  9. A Roadmap for the Human Gut Cell Atlas

    The number of studies investigating the human gastrointestinal tract using various single-cell profiling methods has increased substantially in the...

    Matthias Zilbauer, Kylie R. James, ... Keith T. Wilson in Nature Reviews Gastroenterology & Hepatology
    Article 31 May 2023
  10. Spatial genomics: mapping human steatotic liver disease

    Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as non-alcoholic fatty liver disease) is a leading cause of chronic...

    Kylie P. Matchett, Jasmin Paris, ... Neil C. Henderson in Nature Reviews Gastroenterology & Hepatology
    Article 23 April 2024
  11. Microvascular anastomosis of the human lacrimal gland: a concept study towards transplantation of the human lacrimal gland

    Introduction

    Severe aqueous tear deficiency is caused by primary or secondary main lacrimal gland insufficiency. The transplantation of a human...

    Christoph Holtmann, Mathias Roth, ... Gerd Geerling in Graefe's Archive for Clinical and Experimental Ophthalmology
    Article Open access 07 December 2022
  12. Recombinant human OVGP1 increases intracellular calcium and further potentiates the effects of progesterone on human sperm

    Purpose

    To investigate the effects of recombinant human oviduct–specific glycoprotein (rHuOVGP1) alone and in combination with progesterone (P4) on...

    Sydney C. Vanderkooi, Yuewen Zhao, ... Frederick W. K. Kan in Journal of Assisted Reproduction and Genetics
    Article Open access 16 August 2022
  13. Human Microbiome Clinical Implications and Therapeutic Interventions

    The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital,...
    Sabu Thomas
    Book 2022
  14. Eight Strategies to Engineer Acceptance of Human Germline Modifications

    Until recently, scientific consensus held firm that genetically manipulated embryos created through methods including Mitochondrial Replacement...

    Shoaib Khan, Katherine Drabiak in Journal of Bioethical Inquiry
    Article 31 July 2023
  15. The landscape of transcriptional profiles in human oocytes with different chromatin configurations

    With increasingly used assisted reproductive technology (ART), the acquisition of high-quality oocytes and early embryos has become the focus of much...

    Yi-Ran Zhang, Ying Yin, ... Li-Quan Zhou in Journal of Ovarian Research
    Article Open access 10 May 2024
  16. Emerging roles of noncoding RNAs in human cancers

    Studies have found that RNA encoding proteins only account for a small part of the total number, most RNA is non-coding RNA, and non-coding RNA may...

    Shijie Wu, Yiwen Wu, ... Xiaoyan Yang in Discover Oncology
    Article Open access 13 July 2023
  17. Generation of human gastric assembloids from primary fetal organoids

    Purpose

    Understanding human gastric epithelium homeostasis remains partial, motivating the exploration of innovative in vitro models. Recent...

    Giada Benedetti, Brendan C. Jones, ... Giovanni Giuseppe Giobbe in Pediatric Surgery International
    Article Open access 24 November 2023
  18. Human Rights in Hospitals: an End to Routine Shackling

    Medical students (NSB, NM, JDW) spearheaded revision of the policy and clinical practice for shackling incarcerated patients at Boston Medical Center...

    Neil Singh Bedi, Nisha Mathur, ... Sondra S. Crosby in Journal of General Internal Medicine
    Article Open access 02 January 2024
  19. The Case for Human Challenge Trials in COVID-19

    The COVID-19 pandemic has necessitated rapid research to aid in the understanding of the disease and the development of novel therapeutics. One...

    George P. Drewett in Journal of Bioethical Inquiry
    Article 18 September 2023
  20. Discrimination of human and animal bloodstains using hyperspectral imaging

    Blood is the most encountered type of biological evidence in violent crimes and contains pertinent information to a forensic investigation. The false...

    Gary Sean Cooney, Hannes Köhler, ... Carsten Babian in Forensic Science, Medicine and Pathology
    Article Open access 18 September 2023
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