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Effects of Resveratrol Supplementation on the Cognitive Function of Patients with Alzheimer's Disease: A Systematic Review of Randomized Controlled Trials
BackgroundAlzheimer's disease (AD) comprises 60–70% of diagnosed dementia cases, and is characterized by the deposition of β-amyloid peptide and the...
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Anticholinergic exposure and its association with dementia/Alzheimer's disease and mortality in older adults
BackgroundUse of anticholinergic (ACH) medications is associated with increased risk of cognitive decline in the elderly. However, little is known...
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Evaluating Elements of the Care Partner Experience in Individuals Who Care for People with Alzheimer's Disease Across the Severity Spectrum
IntroductionNon-professional care partners play an important and often evolving role in the care of persons living with Alzheimer’s disease (PLWAD)....
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Parkinson's and Alzheimer's Today About Neurodegeneration and its Therapy
This non-fiction book informs those interested in neuroscience and medicine about the latest findings on the therapy of neurodegeneration with a...
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The Humanistic and Economic Burden of Alzheimer's Disease
Alzheimer’s disease (AD) is the leading cause of cognitive impairment and dementia in older individuals (aged ≥ 65 years) throughout the world. As a...
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Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
Background and aimChuanxiong Renshen decoction (CRD) is a traditional Chinese medicine compound used to treat Alzheimer's disease (AD). However, the...
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Efficacy and safety of brexpiprazole for the treatment of agitation in Alzheimer's disease: a meta-analysis of randomized controlled trials
Recent randomized controlled trials (RCTs) have shown a benefit of brexpiprazole in managing agitation in patients with Alzheimer’s disease (AD)....
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Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task
ObjectiveThis study investigated the visuospatial working memory profiles of behavioural variant frontotemporal dementia (bvFTD) and Alzheimer’s...
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Prediction of cognitive decline in healthy aging based on neuropsychiatric symptoms and PET-biomarkers of Alzheimer's disease
Neuropsychiatric symptoms (NPS) have been associated with a risk of accelerated cognitive decline or conversion to dementia of the Alzheimer’s...
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From allegory to conceptualization, hypothesis and finally evidences: Alzheimer’s dementia, Parkinson's disease "gut–brain axis" and their preclinical phenotype
Researchers are constantly trying to develop therapeutic targets in neurodegenerative disorders like Alzheimer's dementia and Parkinson's disease....
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Diagnostic approach with Z-score mapping to reduce artifacts caused by cerebral atrophy in regional CBF assessment of mild cognitive impairment (MCI) and Alzheimer's disease by [99mTc]-ECD and SPECT
PurposeThe aim of this study was to develop a novel approach that enhanced diagnostic accuracy in the diagnosis of mild cognitive impairment (MCI)...
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The association of night shift work with the risk of all-cause dementia and Alzheimer's disease: a longitudinal study of 245,570 UK Biobank participants
BackgroundThe purpose of this research was to investigate a possible link between night shift work and the development of all-cause dementia and...
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Targeting the molecular web of Alzheimer’s disease: unveiling pathways for effective pharmacotherapy
IntroductionAlzheimer’s disease is a neurocognitive disorder that affects elderly people by slowly impaired cognition, dementia, and gets worse with...
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Correlation between parameters related to sarcopenia and gray matter volume in patients with mild to moderate Alzheimer's disease
BackgroundAlzheimer's disease (AD) is a neurodegenerative disease characterized by brain atrophy and closely correlated with sarcopenia. Mounting...
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Pharmacological Treatment of Alzheimer's Disease Scientific and Clinical Aspects
Alzheimer’s disease is the most prevalent form of dementia. Although it was discovered about a century ago, the first drugs applied in treatment were...
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Associations of Alzheimer's-related plasma biomarkers with cognitive decline in Parkinson's disease
BackgroundParkinson’s disease (PD) is associated with cognitive decline through multiple mechanisms, including Alzheimer’s disease (AD) pathology and...
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Computational and pharmacokinetics studies of 1,3-dimethylbenzimidazolinone analogues of new proposed agent against Alzheimer's disease
BackgroundAlzheimer's disease (AD) is a multifactorial disorder that gradually destroys wisdom and memory skills. Currently, this disease can only be...
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The repetitive transcranial magnetic stimulation in Alzheimer's disease patients with behavioral and psychological symptoms of dementia: a case report
BackgroundRepetitive transcranial magnetic stimulation is a noninvasive intervention, can significantly reduce behavioral and psychological symptoms...
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Alzheimer’s disease and drug delivery across the blood–brain barrier: approaches and challenges
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques...
