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Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains
A key aspect of nutrient absorption is the exquisite division of labour across the length of the small intestine, with individual nutrients taken up...
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The intestine microbiota of shrimp and its impact on cultivation
AbstractIntestinal microbiome contains several times of functional genes compared to the host and mediates the generation of multiple metabolic...
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Intestine bacterial community affects the growth of the Pacific white shrimp (Litopenaeus vannamei)
AbstractIncreasing evidence suggests that intestine microorganisms are closely related to shrimp growth, but there is no existing experiment to prove...
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Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour immunity
Immunotherapy elicits a systemic antitumour immune response in peripheral circulating T cells. However, the T cell trafficking circuit between organs...
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Diet and habitat as determinants of intestine length in fishes
Fish biologists have long assumed a link between intestinal length and diet, and relative gut length or Zihler’s index are often used to classify...
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Optical imaging of the small intestine immune compartment across scales
The limitations of 2D microscopy constrain our ability to observe and understand tissue-wide networks that are, by nature, 3-dimensional. Optical...
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Intestine and spleen microbiota composition in healthy and diseased tilapia
Symbiotic bacteria within the gut microbiome of various organisms, including fish, provide the host with several functions that improve the immune...
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Intrastriatal injection of Parkinson’s disease intestine and vagus lysates initiates α-synucleinopathy in rat brain
Parkinson’s disease (PD) is characterized by the selective loss of dopaminergic neurons in the midbrain and the pathological accumulation of...
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Effect of Nano-selenium on Biological Mechanism of Goblet Cells of the Small Intestine Within Laying Hen
Dietary selenium intake within the normal physiological range is critical for various supporting biological functions. However, the effect of...
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ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway
The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is...
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Disruption of Bioenergetics in the Intestine of Wistar Rats Caused by Hydrogen Sulfide and Thiosulfate: A Potential Mechanism of Chronic Hemorrhagic Diarrhea in Ethylmalonic Encephalopathy
Ethylmalonic encephalopathy (EE) is a severe inherited metabolic disorder that causes tissue accumulation of hydrogen sulfide (sulfide) and...
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Impacts of maternal microbiota and microbial metabolites on fetal intestine, brain, and placenta
BackgroundThe maternal microbiota modulates fetal development, but the mechanisms of these earliest host-microbe interactions are unclear. To...
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Nesterenkonia marinintestina sp. nov., isolated from the fish intestine
A Gram-positive, aerobic, non-motile, irregular short rod, nonspore-forming actinobacterial strain, designated GX14115 T , was isolated from fish...
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Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway
BackgroundOchratoxin A (OTA) is a mycotoxin widely present in raw food and feed materials and is mainly produced by Aspergillus ochraceus and Penicill...
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Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression
Post-translational modifications (PTMs) on histones are a key source of regulation on chromatin through impacting cellular processes, including gene...
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Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis
BackgroundAlthough obesity is caused by different factors, individual susceptibility to obesity differs among people under the same circumstances....
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Effect of In Ovo Trace Element Supplementation on Immune-Related Cells of the Small Intestine of Post-hatched Broiler Chicken
Pathological conditions and harmful drugs cause many gastrointestinal diseases in broiler chicken. The current study was conducted to investigate the...
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Toxic effects of naproxen on the intestine of the goldfish, Carassius auratus
BackgroundExtensive use of the non-steroidal anti-inflammatory drug (NSAID) naproxen greatly increases the likelihood of its release into the ambient...
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Long-term hypoxia stress-induced oxidative stress, cell apoptosis, and immune response in the intestine of Pelteobagrus vachelli
Hypoxia is a common phenomenon in aquaculture. With the dissolved oxygen (DO) 3.75 ± 0.25 mg O 2 /L for hypoxia group and 7.25 ± 0.25 mg O 2 /L for...
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Integrative Analysis of the Microbiome and Metabolome of Broiler Intestine: Insights into the Mechanisms of Probiotic Action as an Antibiotic Substitute
Antibiotic substitutes have become a research focus due to restrictions on antibiotic usage. Among the antibiotic substitutes on the market,...