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  1. Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

    A key aspect of nutrient absorption is the exquisite division of labour across the length of the small intestine, with individual nutrients taken up...

    Rachel K. Zwick, Petr Kasparek, ... Ophir D. Klein in Nature Cell Biology
    Article 06 February 2024
  2. The intestine microbiota of shrimp and its impact on cultivation

    Abstract

    Intestinal microbiome contains several times of functional genes compared to the host and mediates the generation of multiple metabolic...

    Shenzheng Zeng, Jianguo He, Zhijian Huang in Applied Microbiology and Biotechnology
    Article Open access 06 June 2024
  3. Intestine bacterial community affects the growth of the Pacific white shrimp (Litopenaeus vannamei)

    Abstract

    Increasing evidence suggests that intestine microorganisms are closely related to shrimp growth, but there is no existing experiment to prove...

    Dongwei Hou, Bin Yin, ... Zhijian Huang in Applied Microbiology and Biotechnology
    Article 05 January 2024
  4. Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour immunity

    Immunotherapy elicits a systemic antitumour immune response in peripheral circulating T cells. However, the T cell trafficking circuit between organs...

    Rong-Yi Shi, Neng Zhou, ... Cai-Wen Duan in Nature Cell Biology
    Article 22 July 2024
  5. Diet and habitat as determinants of intestine length in fishes

    Fish biologists have long assumed a link between intestinal length and diet, and relative gut length or Zihler’s index are often used to classify...

    Maria J. Duque-Correa, Kendall D. Clements, ... Marcus Clauss in Reviews in Fish Biology and Fisheries
    Article Open access 12 April 2024
  6. Optical imaging of the small intestine immune compartment across scales

    The limitations of 2D microscopy constrain our ability to observe and understand tissue-wide networks that are, by nature, 3-dimensional. Optical...

    Arielle Louise Planchette, Cédric Schmidt, ... Jérôme Extermann in Communications Biology
    Article Open access 31 March 2023
  7. Intestine and spleen microbiota composition in healthy and diseased tilapia

    Symbiotic bacteria within the gut microbiome of various organisms, including fish, provide the host with several functions that improve the immune...

    Tamir Ofek, Maya Lalzar, ... Malka Halpern in Animal Microbiome
    Article Open access 13 August 2022
  8. Intrastriatal injection of Parkinson’s disease intestine and vagus lysates initiates α-synucleinopathy in rat brain

    Parkinson’s disease (PD) is characterized by the selective loss of dopaminergic neurons in the midbrain and the pathological accumulation of...

    Zhaofei Yang, Ying Wang, ... Weidong Le in Cell Death & Disease
    Article Open access 05 January 2023
  9. Effect of Nano-selenium on Biological Mechanism of Goblet Cells of the Small Intestine Within Laying Hen

    Dietary selenium intake within the normal physiological range is critical for various supporting biological functions. However, the effect of...

    Yongxiang Yin, Nisar Ahmed, ... Jue Lyu in Biological Trace Element Research
    Article 16 July 2023
  10. ACE2 mediates tryptophan alleviation on diarrhea by repairing intestine barrier involved mTOR pathway

    The membrane-delimited receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), angiotensin-converting enzyme 2 (ACE2), which is...

    Jinze Li, Yingli Yan, ... Wence Wang in Cellular & Molecular Biology Letters
    Article Open access 14 June 2024
  11. Disruption of Bioenergetics in the Intestine of Wistar Rats Caused by Hydrogen Sulfide and Thiosulfate: A Potential Mechanism of Chronic Hemorrhagic Diarrhea in Ethylmalonic Encephalopathy

    Ethylmalonic encephalopathy (EE) is a severe inherited metabolic disorder that causes tissue accumulation of hydrogen sulfide (sulfide) and...

    Marina Rocha Frusciante, Marian Flores Signori, ... Guilhian Leipnitz in Cell Biochemistry and Biophysics
    Article 17 August 2023
  12. Impacts of maternal microbiota and microbial metabolites on fetal intestine, brain, and placenta

    Background

    The maternal microbiota modulates fetal development, but the mechanisms of these earliest host-microbe interactions are unclear. To...

    Aleksi Husso, Tiina Pessa-Morikawa, ... Mikael Niku in BMC Biology
    Article Open access 04 October 2023
  13. Nesterenkonia marinintestina sp. nov., isolated from the fish intestine

    A Gram-positive, aerobic, non-motile, irregular short rod, nonspore-forming actinobacterial strain, designated GX14115 T , was isolated from fish...

    Aolin Zhao, Hanqin Cai, ... Wenshan Huang in Archives of Microbiology
    Article 19 February 2024
  14. Ochratoxin A induces abnormal tryptophan metabolism in the intestine and liver to activate AMPK signaling pathway

    Background

    Ochratoxin A (OTA) is a mycotoxin widely present in raw food and feed materials and is mainly produced by Aspergillus ochraceus and Penicill...

    Weiqing Ma, Yang Fu, ... Wence Wang in Journal of Animal Science and Biotechnology
    Article Open access 08 September 2023
  15. Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression

    Post-translational modifications (PTMs) on histones are a key source of regulation on chromatin through impacting cellular processes, including gene...

    Leah A. Gates, Bernardo Sgarbi Reis, ... C. David Allis in Nature Metabolism
    Article 27 February 2024
  16. Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis

    Background

    Although obesity is caused by different factors, individual susceptibility to obesity differs among people under the same circumstances....

    Yueshan Pang, Yali Zheng, ... WeiJun Ding in Lipids in Health and Disease
    Article Open access 08 October 2022
  17. Effect of In Ovo Trace Element Supplementation on Immune-Related Cells of the Small Intestine of Post-hatched Broiler Chicken

    Pathological conditions and harmful drugs cause many gastrointestinal diseases in broiler chicken. The current study was conducted to investigate the...

    Fazul Nabi, Muhammad Asif Arain, ... Juan Liu in Biological Trace Element Research
    Article 19 November 2022
  18. Toxic effects of naproxen on the intestine of the goldfish, Carassius auratus

    Background

    Extensive use of the non-steroidal anti-inflammatory drug (NSAID) naproxen greatly increases the likelihood of its release into the ambient...

    Jing Wang, Weijing Kong, ... Zhenguang Yan in Molecular & Cellular Toxicology
    Article 12 October 2022
  19. Long-term hypoxia stress-induced oxidative stress, cell apoptosis, and immune response in the intestine of Pelteobagrus vachelli

    Hypoxia is a common phenomenon in aquaculture. With the dissolved oxygen (DO) 3.75 ± 0.25 mg O 2 /L for hypoxia group and 7.25 ± 0.25 mg O 2 /L for...

    Min Wang, Shujia Liao, ... Tao Wang in Fish Physiology and Biochemistry
    Article 24 May 2023
  20. Integrative Analysis of the Microbiome and Metabolome of Broiler Intestine: Insights into the Mechanisms of Probiotic Action as an Antibiotic Substitute

    Antibiotic substitutes have become a research focus due to restrictions on antibiotic usage. Among the antibiotic substitutes on the market,...

    Yang Li, Jian-Ling Zhang, ... Zhi-Lin Wang in Probiotics and Antimicrobial Proteins
    Article 21 June 2024
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