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Yak genome database: a multi-omics analysis platform
BackgroundThe yak ( Bos grunniens ) is a large ruminant species that lives in high-altitude regions and exhibits excellent adaptation to the plateau...
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Genetic diversity, phylogeography, and maternal origin of yak (Bos grunniens)
BackgroundThere is no consensus as to the origin of the domestic yak ( Bos grunniens ). Previous studies on yak mitochondria mainly focused on...
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Permafrost preservation reveals proteomic evidence for yak milk consumption in the 13th century
Domesticated yaks endure as iconic symbols of high-altitude frozen landscapes, where herding communities depend on their high-fat milk, transport,...
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Genome-wide identification of SNPs associated with body weight in yak
BackgroundThe yak is the most important livestock in the Qinghai-Tibet Plateau, and body weight directly affects the economic values of yak. Up to...
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Characterization of a unique Sikkimese yak population of India: a multivariate approach
Native Sikkimese yak in Sikkim state of India is a pastoral treasure being raised through centuries-old transhumance practices and has evolved in...
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Integrative analysis of Iso-Seq and RNA-seq data reveals transcriptome complexity and differential isoform in skin tissues of different hair length Yak
BackgroundThe hair follicle development process is regulated by sophisticated genes and signaling networks, and the hair grows from the hair...
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Screening, Identification, and Probiotic Properties of Bacillus Pumilus From Yak
The yak has a unique physiological structure suited to life in anoxic and cold environments at high altitudes. The aim of this study was to isolate Bacillus...
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Single-cell transcriptome analysis and in vitro differentiation of testicular cells reveal novel insights into male sterility of the interspecific hybrid cattle-yak
BackgroundInterspecific hybridization plays vital roles in enriching animal diversity, while male hybrid sterility (MHS) of the offspring commonly...
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Genome-wide detection of RNA editing events during the hair follicles cycle of Tianzhu white yak
BackgroundThe hair coat is available for the yak to live in the harsh environment of the plateau. Besides, improving the hair production of yak is...
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Transcriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage
To gain a deeper understanding of the metabolic differences within and outside the body, as well as changes in transcription levels following estrus...
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Effects of the alpine meadow in different phenological periods on rumen fermentation and gastrointestinal tract bacteria community in grazing yak on the Qinghai-Tibetan Plateau
BackgroundIn this study, we investigated the effects of alpine meadow in different phenological periods on ruminal fermentation, serum biochemical...
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Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
BackgroundAs the direct organ of villus, hair follicles have obvious seasonal cycles. The hair follicle cycle is orchestrated by multiple cell types...
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Transmission of fungi and protozoa under grazing conditions from lactating yaks to sucking yak calves in early life
AbstractMicrobiota from mothers is an essential source of microbes in early-life rumen microbiota, but the contribution of microbiota from different...
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The transcriptome-wide N6-methyladenosine (m6A) map profiling reveals the regulatory role of m6A in the yak ovary
Background and aimYak estrus is a seasonal phenomenon, probably involving epigenetic regulation of synthesis and secretion of sex hormones as well as...
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Simulated Yak and Tibetan Sheep Urine Deposition Fleetingly Promoted N2O, CO2 and CH4 Emissions in an Alpine Steppe of Northern Xizang Plateau
The urine of yaks ( Bos grunniens ) and Tibetan sheep ( Pantholops hodgsoni ) represents a vital source of nutrients in the alpine grasslands on the...
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Metabolomics and proteomics insights into subacute ruminal acidosis etiology and inhibition of proliferation of yak rumen epithelial cells in vitro
BackgroundUntargeted metabolomics and proteomics were employed to investigate the intracellular response of yak rumen epithelial cells (YRECs) to...
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Effects of PHD and HSP90 on erythropoietin production in yak (Bos grunniens) renal interstitial fibroblast-like cells under hypoxia
Erythropoietin (EPO), a central protein of erythropoiesis, plays an important role during hypoxia adaptation and is regulated by hypoxia-inducible...
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Mitogenomic diversity and phylogeny analysis of yak (Bos grunniens)
Background and aimMitochondrial genome has aseries of characteristics such as simple structure, no recombination, maternalinheritance, stable...
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Integrated analysis of the expression profiles of the lncRNA-miRNA-mRNA ceRNA network in granulosa and cumulus cells from yak ovaries
BackgroundGrowing oocytes acquire the ability to mature through two-way communication between gametes and surrounding somatic cumulus cells (CCs)....
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Effects of Probiotic Enterococcus faecium from Yak on the Intestinal Microflora and Metabolomics of Mice with Salmonella Infection
Salmonella spp. are pathogenic bacteria that cause diarrhea, abortion, and death in yak and severely harm livestock breeding. Therefore, it is vital...
