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Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information
BackgroundCorrelation metrics are widely utilized in genomics analysis and often implemented with little regard to assumptions of normality,...
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Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis
BackgroundFinding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly...
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Gene regulation network inference using k-nearest neighbor-based mutual information estimation: revisiting an old DREAM
BackgroundA cell exhibits a variety of responses to internal and external cues. These responses are possible, in part, due to the presence of an...
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Filtering ASVs/OTUs via mutual information-based microbiome network analysis
Microbial communities are widely studied using high-throughput sequencing techniques, such as 16S rRNA gene sequencing. These techniques have...
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ScInfoVAE: interpretable dimensional reduction of single cell transcription data with variational autoencoders and extended mutual information regularization
Single-cell RNA-sequencing (scRNA-seq) data can serve as a good indicator of cell-to-cell heterogeneity and can aid in the study of cell growth by...
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First record of mutual allogrooming in wild northern red muntjac Muntiacus Vaginalis
We report the first record of mutual allogrooming in free-ranging wild northern red muntjac ( Muntiacus vaginalis ) from dense tropical forests of...
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Predation dynamics and mutual interference among ladybird beetles in managing Diaspis echinocacti (Bouché) infestation on Opuntia spp
Diaspis echinocacti (Bouché) poses a significant threat to Opuntia spp. worldwide, highlighting the critical need for effective control measures....
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Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction
MicroRNA (miRNA) serves as a pivotal regulator of numerous cellular processes, and the identification of miRNA-disease associations (MDAs) is crucial...
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Separate and Mutual Effects of BIRB796 and Bortezomib on pHsp27 and Viability of U87MG Glioma Cells
AbstractHsp27 phosphorylation is associated with many pathways in glioma, such as tumor cell proliferation and apoptosis inhibition. The aim of this...
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FCMEDriver: Identifying Cancer Driver Gene by Combining Mutual Exclusivity of Embedded Features and Optimized Mutation Frequency Score
Efficiently identifying cancer driver genes is critical to drug design, cancer diagnosis and treatment. Current unsupervised cancer driver gene... -
Mutual induced-fit mechanism drives binding between intrinsically disordered Bim and cryptic binding site of Bcl-xL
The intrinsically disordered region (IDR) of Bim binds to the flexible cryptic site of Bcl-xL, a pro-survival protein involved in cancer progression...
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Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth
Glioblastoma (GBM) is a highly vascular malignant brain tumor that overexpresses vascular endothelial growth factor (VEGF) and phosphofructokinase 1...
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Multivariate information theory uncovers synergistic subsystems of the human cerebral cortex
One of the most well-established tools for modeling the brain is the functional connectivity network, which is constructed from pairs of interacting...
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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction
The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is...
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Mutual generation in neuronal activity across the brain via deep neural approach, and its network interpretation
In the brain, many regions work in a network-like association, yet it is not known how durable these associations are in terms of activity and could...
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Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information
Neurons can carry information with both the synchrony and rate of their spikes. However, it is unknown whether distinct subtypes of neurons are more...
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A food safety prescreening method with domain-specific information using online reviews
Food contamination and food poisoning are presenting a substantial safety risk to consumers worldwide. In the era of information quantity and...
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ARCTIC-3D: automatic retrieval and clustering of interfaces in complexes from 3D structural information
The formation of a stable complex between proteins lies at the core of a wide variety of biological processes and has been the focus of countless...
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Social information-mediated population dynamics in non-grouping prey
AbstractInadvertent social information (ISI) use, i.e., the exploitation of social cues including the presence and behaviour of others, has been...
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Mutual mother–pup vocal recognition in the highly colonial Cape fur seal: evidence of discrimination of calls with a high acoustic similarity
The Cape fur seal ( Arctocephalus pusillus pusillus ) is one of the most colonial mammal species in the world. Females exclusively nurse their pups for...