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  1. Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information

    Background

    Correlation metrics are widely utilized in genomics analysis and often implemented with little regard to assumptions of normality,...

    Cullen Roth, Vrinda Venu, ... Shawn R. Starkenburg in BMC Bioinformatics
    Article Open access 22 November 2023
  2. Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis

    Background

    Finding correlation patterns is an important goal of analyzing biological data. Currently available methods for correlation analysis mainly...

    Yi-Hua Jiang, Jie Long, ... Jia-Rui Wu in BMC Bioinformatics
    Article Open access 24 May 2022
  3. Gene regulation network inference using k-nearest neighbor-based mutual information estimation: revisiting an old DREAM

    Background

    A cell exhibits a variety of responses to internal and external cues. These responses are possible, in part, due to the presence of an...

    Lior I. Shachaf, Elijah Roberts, ... Jie Xiao in BMC Bioinformatics
    Article Open access 06 March 2023
  4. Filtering ASVs/OTUs via mutual information-based microbiome network analysis

    Microbial communities are widely studied using high-throughput sequencing techniques, such as 16S rRNA gene sequencing. These techniques have...

    Elham Bayat Mokhtari, Benjamin Jerry Ridenhour in BMC Bioinformatics
    Article Open access 16 September 2022
  5. ScInfoVAE: interpretable dimensional reduction of single cell transcription data with variational autoencoders and extended mutual information regularization

    Single-cell RNA-sequencing (scRNA-seq) data can serve as a good indicator of cell-to-cell heterogeneity and can aid in the study of cell growth by...

    Weiquan Pan, Faning Long, Jian Pan in BioData Mining
    Article Open access 10 June 2023
  6. First record of mutual allogrooming in wild northern red muntjac Muntiacus Vaginalis

    We report the first record of mutual allogrooming in free-ranging wild northern red muntjac ( Muntiacus vaginalis ) from dense tropical forests of...

    Harshvardhan Singh Rathore, Jagyandatt Pati, ... Samrat Mondol in acta ethologica
    Article 07 June 2024
  7. Predation dynamics and mutual interference among ladybird beetles in managing Diaspis echinocacti (Bouché) infestation on Opuntia spp

    Diaspis echinocacti (Bouché) poses a significant threat to Opuntia spp. worldwide, highlighting the critical need for effective control measures....

    Mohamed El Aalaoui, Said Rammali, Mohamed Sbaghi in International Journal of Tropical Insect Science
    Article 08 April 2024
  8. Synchronous Mutual Learning Network and Asynchronous Multi-Scale Embedding Network for miRNA-Disease Association Prediction

    MicroRNA (miRNA) serves as a pivotal regulator of numerous cellular processes, and the identification of miRNA-disease associations (MDAs) is crucial...

    Weicheng Sun, Ping Zhang, ... Li Li in Interdisciplinary Sciences: Computational Life Sciences
    Article 04 February 2024
  9. Separate and Mutual Effects of BIRB796 and Bortezomib on pHsp27 and Viability of U87MG Glioma Cells

    Abstract

    Hsp27 phosphorylation is associated with many pathways in glioma, such as tumor cell proliferation and apoptosis inhibition. The aim of this...

    Sevde Nur Biltekin, Evren Önay Uçar in Biology Bulletin
    Article 10 August 2023
  10. FCMEDriver: Identifying Cancer Driver Gene by Combining Mutual Exclusivity of Embedded Features and Optimized Mutation Frequency Score

    Efficiently identifying cancer driver genes is critical to drug design, cancer diagnosis and treatment. Current unsupervised cancer driver gene...
    Sichen Yi, MinZhu Xie in Bioinformatics Research and Applications
    Conference paper 2024
  11. Mutual induced-fit mechanism drives binding between intrinsically disordered Bim and cryptic binding site of Bcl-xL

    The intrinsically disordered region (IDR) of Bim binds to the flexible cryptic site of Bcl-xL, a pro-survival protein involved in cancer progression...

    Gert-Jan Bekker, Mitsugu Araki, ... Narutoshi Kamiya in Communications Biology
    Article Open access 30 March 2023
  12. Mutual regulation between phosphofructokinase 1 platelet isoform and VEGF promotes glioblastoma tumor growth

    Glioblastoma (GBM) is a highly vascular malignant brain tumor that overexpresses vascular endothelial growth factor (VEGF) and phosphofructokinase 1...

    Je Sun Lim, YuJie Shi, ... Jong-Ho Lee in Cell Death & Disease
    Article Open access 26 November 2022
  13. Multivariate information theory uncovers synergistic subsystems of the human cerebral cortex

    One of the most well-established tools for modeling the brain is the functional connectivity network, which is constructed from pairs of interacting...

    Thomas F. Varley, Maria Pope, ... Olaf Sporns in Communications Biology
    Article Open access 24 April 2023
  14. Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction

    The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is...

    Ricarda Breitmeyer, Sabrina Vogel, ... Hansjürgen Volkmer in Communications Biology
    Article Open access 29 April 2023
  15. Mutual generation in neuronal activity across the brain via deep neural approach, and its network interpretation

    In the brain, many regions work in a network-like association, yet it is not known how durable these associations are in terms of activity and could...

    Ryota Nakajima, Arata Shirakami, ... Masanori Shimono in Communications Biology
    Article Open access 31 October 2023
  16. Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information

    Neurons can carry information with both the synchrony and rate of their spikes. However, it is unknown whether distinct subtypes of neurons are more...

    Luke Y. Prince, Matthew M. Tran, ... Blake A. Richards in Communications Biology
    Article Open access 05 August 2021
  17. A food safety prescreening method with domain-specific information using online reviews

    Food contamination and food poisoning are presenting a substantial safety risk to consumers worldwide. In the era of information quantity and...

    Enguang Zuo, Alimjan Aysa, ... Kurban Ubul in Journal of Consumer Protection and Food Safety
    Article 18 March 2022
  18. ARCTIC-3D: automatic retrieval and clustering of interfaces in complexes from 3D structural information

    The formation of a stable complex between proteins lies at the core of a wide variety of biological processes and has been the focus of countless...

    Marco Giulini, Rodrigo V. Honorato, ... Alexandre M. J. J. Bonvin in Communications Biology
    Article Open access 06 January 2024
  19. Social information-mediated population dynamics in non-grouping prey

    Abstract

    Inadvertent social information (ISI) use, i.e., the exploitation of social cues including the presence and behaviour of others, has been...

    Zoltán Tóth, Gabriella Kőmüves in Behavioral Ecology and Sociobiology
    Article Open access 04 August 2022
  20. Mutual mother–pup vocal recognition in the highly colonial Cape fur seal: evidence of discrimination of calls with a high acoustic similarity

    The Cape fur seal ( Arctocephalus pusillus pusillus ) is one of the most colonial mammal species in the world. Females exclusively nurse their pups for...

    Mathilde Martin, Tess Gridley, ... Isabelle Charrier in Animal Cognition
    Article 04 May 2022
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