Search
Search Results
-
Cell and Molecular Biology of Ovarian Cancer Updates, Insights and New Frontiers
The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular &...
-
The Role of the Human Microbiome in Epithelial Ovarian Cancer
Ovarian cancer is the fifth-leading cause of cancer deaths among women due to the absence of available screening methods to identify early disease.... -
The Impact of Mitochondria in Ovarian Cancer Cell Metabolism, Proliferation, and Metastasis
Mitochondrial dysfunctions are significantly implicated in cancer initiation, progression, and metastasis, which have been shown for several cancers... -
Drug-Resistant Epithelial Ovarian Cancer: Current and Future Perspectives
Epithelial ovarian cancer (EOC) is a complex disease with diverse histological subtypes, which, based on the aggressiveness and course of disease... -
EMP1 correlated with cancer progression and immune characteristics in pan-cancer and ovarian cancer
This study examines the prognostic role and immunological relevance of EMP1 (epithelial membrane protein-1) in a pan-cancer analysis, with a focus on...
-
Insights into the Microbial Composition of Intratumoral, Reproductive Tract, and Gut Microbiota in Ovarian Cancer Patients
According to the latest global cancer data, ovarian cancer is the deadliest among all gynecological malignant tumors and ranks fifth in terms of... -
The emerging roles of miRNA-mediated autophagy in ovarian cancer
Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early...
-
Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness
In ovarian tumors, the omental microenvironment profoundly influences the behavior of cancer cells and sustains the acquisition of stem-like traits,...
-
STAT3 mediates ECM stiffness-dependent progression in ovarian cancer
The treatment of ovarian cancer remains a medical challenge and its malignant progression is connected with obvious changes in both tissue and cell...
-
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway
Early detection and effective chemotherapy for ovarian cancer, a serious gynecological malignancy, require further progress. This study aimed to...
-
CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α
Ovarian cancer is the most lethal malignancy among gynecologic cancers, and primary and secondary chemotherapy resistance is one of the important...
-
XTP8 Promotes Ovarian Cancer Progression by Activating AKT/AMPK/mTOR Pathway to Regulate EMT
Ovarian cancer (OC) ranks as the fifth leading cause of cancer-related death in women. The main contributors to the poor prognosis of ovarian cancer...
-
Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion
Bromodomain-containing protein 4 (BRD4), the major component of bromodomain and extra-terminal domain (BET) protein family, has important functions...
-
The senescent mesothelial matrix accentuates colonization by ovarian cancer cells
Ovarian cancer is amongst the most morbid of gynecological malignancies due to its diagnosis at an advanced stage, a transcoelomic mode of...
-
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway
The incidence rate of developing ovarian cancer decreases over the years; however, mortality ranks top among malignancies of women, mainly metastasis...
-
Advances in application of circulating tumor DNA in ovarian cancer
Ovarian cancer is the third most common gynecologic cancer worldwide and has the highest mortality rate among gynecologic cancers. Identifying timely...
-
Clinical and translational advances in ovarian cancer therapy
Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and is initially very responsive to platinum-based...
-
Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
Mitochondria are dynamic organelles that are important for cell growth and proliferation. Dysregulated mitochondrial dynamics are highly associated...
-
Inhibition of SF3B1 improves the immune microenvironment through pyroptosis and synergizes with αPDL1 in ovarian cancer
Ovarian cancer is resistant to immune checkpoint blockade (ICB) treatment. Combination of targeted therapy and immunotherapy is a promising strategy...
-
VCAM-1 complements CA-125 in detecting recurrent ovarian cancer
BackgroundClose to three-quarters of ovarian cancer cases are frequently diagnosed at an advanced stage, with more than 70% of them failing to...