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  1. Cell and Molecular Biology of Ovarian Cancer Updates, Insights and New Frontiers

    The first of two companion books addressed the biology and clinical aspects of ovarian cancer. The companion title, Ovarian Cancer: Molecular &...

    Book 2024
  2. The Role of the Human Microbiome in Epithelial Ovarian Cancer

    Ovarian cancer is the fifth-leading cause of cancer deaths among women due to the absence of available screening methods to identify early disease....
    Chapter 2024
  3. The Impact of Mitochondria in Ovarian Cancer Cell Metabolism, Proliferation, and Metastasis

    Mitochondrial dysfunctions are significantly implicated in cancer initiation, progression, and metastasis, which have been shown for several cancers...
    Chapter 2024
  4. Drug-Resistant Epithelial Ovarian Cancer: Current and Future Perspectives

    Epithelial ovarian cancer (EOC) is a complex disease with diverse histological subtypes, which, based on the aggressiveness and course of disease...
    Megha Mehrotra, Pratham Phadte, ... Pritha Ray in Cell and Molecular Biology of Ovarian Cancer
    Chapter 2024
  5. EMP1 correlated with cancer progression and immune characteristics in pan-cancer and ovarian cancer

    This study examines the prognostic role and immunological relevance of EMP1 (epithelial membrane protein-1) in a pan-cancer analysis, with a focus on...

    Jun Zhang, Jing Yang, ... Yindi Bao in Molecular Genetics and Genomics
    Article 14 May 2024
  6. Insights into the Microbial Composition of Intratumoral, Reproductive Tract, and Gut Microbiota in Ovarian Cancer Patients

    According to the latest global cancer data, ovarian cancer is the deadliest among all gynecological malignant tumors and ranks fifth in terms of...
    Chapter 2024
  7. The emerging roles of miRNA-mediated autophagy in ovarian cancer

    Ovarian cancer is one of the common tumors of the female reproductive organs. It has a high mortality rate, is highly heterogeneous, and early...

    Yamin Ding, Xuan Huang, ... Rongbin Wei in Cell Death & Disease
    Article Open access 03 May 2024
  8. Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness

    In ovarian tumors, the omental microenvironment profoundly influences the behavior of cancer cells and sustains the acquisition of stem-like traits,...

    Chiara Battistini, Hilary A. Kenny, ... Ugo Cavallaro in Cell Death & Disease
    Article Open access 28 May 2024
  9. STAT3 mediates ECM stiffness-dependent progression in ovarian cancer

    The treatment of ovarian cancer remains a medical challenge and its malignant progression is connected with obvious changes in both tissue and cell...

    Sun Chenchen, Qian Xueqian, ... Han Yangyang in Molecular and Cellular Biochemistry
    Article 16 April 2024
  10. ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway

    Early detection and effective chemotherapy for ovarian cancer, a serious gynecological malignancy, require further progress. This study aimed to...

    Shien Mo, Tingji Liu, ... Yan Kuang in Molecular and Cellular Biochemistry
    Article Open access 12 May 2024
  11. CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α

    Ovarian cancer is the most lethal malignancy among gynecologic cancers, and primary and secondary chemotherapy resistance is one of the important...

    Xin Fu, Qian Zhang, ... Qiuping Dong in Cell Death & Disease
    Article Open access 09 January 2024
  12. XTP8 Promotes Ovarian Cancer Progression by Activating AKT/AMPK/mTOR Pathway to Regulate EMT

    Ovarian cancer (OC) ranks as the fifth leading cause of cancer-related death in women. The main contributors to the poor prognosis of ovarian cancer...

    Ruixue Zhao, Xin Ning, ... Rong Ma in Cell Biochemistry and Biophysics
    Article Open access 13 March 2024
  13. Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion

    Bromodomain-containing protein 4 (BRD4), the major component of bromodomain and extra-terminal domain (BET) protein family, has important functions...

    Yi Liu, Hejing Liu, ... Xueqiong Zhu in Cell Death & Disease
    Article Open access 22 September 2023
  14. The senescent mesothelial matrix accentuates colonization by ovarian cancer cells

    Ovarian cancer is amongst the most morbid of gynecological malignancies due to its diagnosis at an advanced stage, a transcoelomic mode of...

    Bharat Vivan Thapa, Mallar Banerjee, ... Ramray Bhat in Cellular and Molecular Life Sciences
    Article Open access 03 December 2023
  15. MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway

    The incidence rate of developing ovarian cancer decreases over the years; however, mortality ranks top among malignancies of women, mainly metastasis...

    Jingbo Liu, Jing Zhang, ... Youguo Chen in Functional & Integrative Genomics
    Article 03 April 2024
  16. Advances in application of circulating tumor DNA in ovarian cancer

    Ovarian cancer is the third most common gynecologic cancer worldwide and has the highest mortality rate among gynecologic cancers. Identifying timely...

    Ting Xia, Chenyan Fang, Yaqing Chen in Functional & Integrative Genomics
    Article 21 July 2023
  17. Clinical and translational advances in ovarian cancer therapy

    Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and is initially very responsive to platinum-based...

    Panagiotis A. Konstantinopoulos, Ursula A. Matulonis in Nature Cancer
    Article 31 August 2023
  18. Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer

    Mitochondria are dynamic organelles that are important for cell growth and proliferation. Dysregulated mitochondrial dynamics are highly associated...

    Yaqin Zhu, Yue Wang, ... Huanjie Shao in Communications Biology
    Article Open access 08 June 2023
  19. Inhibition of SF3B1 improves the immune microenvironment through pyroptosis and synergizes with αPDL1 in ovarian cancer

    Ovarian cancer is resistant to immune checkpoint blockade (ICB) treatment. Combination of targeted therapy and immunotherapy is a promising strategy...

    Shourong Wang, Yao Liu, ... Kun Song in Cell Death & Disease
    Article Open access 27 November 2023
  20. VCAM-1 complements CA-125 in detecting recurrent ovarian cancer

    Background

    Close to three-quarters of ovarian cancer cases are frequently diagnosed at an advanced stage, with more than 70% of them failing to...

    Jin Song, Lori J. Sokoll, ... Daniel W. Chan in Clinical Proteomics
    Article Open access 25 June 2023
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