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Mitochondria and Ageing
Aging is a complex and multifactorial process, characterized by a progressive decline of energy metabolism and physiological functions. Although...
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The potency of mitochondria enlargement for mitochondria-mediated terpenoid production in yeast
AbstractTerpenoids are widely used in the food, beverage, cosmetics, and pharmaceutical industries. Microorganisms have been extensively studied for...
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Mitochondria and cell death
Mitochondria are cellular factories for energy production, calcium homeostasis and iron metabolism, but they also have an unequivocal and central...
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Mitochondria transcription and cancer
Mitochondria are major organelles involved in several processes related to energy supply, metabolism, and cell proliferation. The mitochondria...
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Plant Mitochondria Methods and Protocols
This detailed volume presents a wide range of techniques for plant mitochondrial analysis, ranging from tried-and-tested work horse techniques to the...
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Monitoring Mitochondria Function in Ferroptosis
Ferroptosis is a type of regulated necrosis driven by uncontrolled membrane lipid peroxidation. Mitochondria, which are membrane-bound organelles...
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Defects of mitochondria-lysosomes communication induce secretion of mitochondria-derived vesicles and drive chemoresistance in ovarian cancer cells
BackgroundAmong the mechanisms of mitochondrial quality control (MQC), generation of mitochondria-derived vesicles (MDVs) is a process to avoid...
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Mitochondria and telomeres: hand in glove
Born as an endosymbiont, the bacteria engulfed by the proto-eukaryotic cell more than 1.45 billion years ago progressively evolved as an important...
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Functional transformation of macrophage mitochondria in cardiovascular diseases
Mitochondria are pivotal in the modulation of macrophage activation, differentiation, and survival. Furthermore, macrophages are instrumental in the...
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Mitochondria Methods and Protocols
This volume details comprehensive protocols and methodologies to assess mitochondrial bioenergetics and dynamics in different tissues and cells...
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Enhanced ROS Production in Mitochondria from Prematurely Aging mtDNA Mutator Mice
AbstractAn increase in mitochondrial DNA (mtDNA) mutations and an ensuing increase in mitochondrial reactive oxygen species (ROS) production have...
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Mitochondria, metabolism, and aging in yeast
Quantitative and qualitative changes in metabolism take place when the lifespan is extended in yeast either by genetic or nutritional manipulation....
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Generation and Fate of ROS in Mitochondria
Mitochondria, the powerhouse of the cell, perform the function of cellular respiration. The tricarboxylic acid cycle (TCA) and electron transport...
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An Insight into the Approach Taken to Appurtenances Disorders Linked to Mitochondria
AbstractMitochondria are essential components of bioenergetic and biosynthetic pathways and are capable of making quick adjustments to accommodate...
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Mitochondria as central hubs in synaptic modulation
Mitochondria are present in the pre- and post-synaptic regions, providing the energy required for the activity of these very specialized neuronal...
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Membrane-Active Mitochondria-Targeted Antitumor Agents and Drug Delivery Systems
Abstract —Mitochondria are the “power stations” of cells. Without them, the normal functioning of a living cell is impossible. This organelle is an...
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Isolating Mitochondria, Mitoplasts, and mtDNA from Cultured Mammalian Cells
Mitochondria are double membrane-bound eukaryotic organelles with roles in a range of cellular activities including energy conversion, apoptosis,...
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GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity
The transfer of intact mitochondria between heterogeneous cell types has been confirmed in various settings, including cancer. However, the...
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The multiple links between actin and mitochondria
Actin plays many well-known roles in cells, and understanding any specific role is often confounded by the overlap of multiple actin-based structures...
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The diversified role of mitochondria in ferroptosis in cancer
Ferroptosis is a form of regulated cell death induced by iron-dependent lipid peroxidation, and it has been studied extensively since its discovery...
